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Entry version 101 (10 Feb 2021)
Sequence version 1 (01 Nov 1996)
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Protein

Muscle calcium channel subunit alpha-1

Gene
N/A
Organism
Musca domestica (House fly)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death (By similarity). MDL-alpha1 encodes a dihydropyridine- and diltiazem-sensitive current in larval body wall muscle.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei285Calcium ion selectivity and permeabilityBy similarity1
Sitei617Calcium ion selectivity and permeabilityBy similarity1
Sitei1005Calcium ion selectivity and permeabilityBy similarity1
Sitei1311Calcium ion selectivity and permeabilityBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi1398 – 1409By similarityAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCalcium channel, Ion channel, Voltage-gated channel
Biological processCalcium transport, Ion transport, Transport
LigandCalcium, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Muscle calcium channel subunit alpha-1
Alternative name(s):
MDL-alpha-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMusca domestica (House fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7370 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaMuscoideaMuscidaeMusca
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000095301 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Whole Genome Shotgun Assembly

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:MDOA002080
VectorBase:MDOA005409
VectorBase:MDOA010384
VectorBase:MDOA014412

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 61CytoplasmicSequence analysisAdd BLAST61
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei62 – 80Helical; Name=S1 of repeat ISequence analysisAdd BLAST19
Topological domaini81 – 99ExtracellularSequence analysisAdd BLAST19
Transmembranei100 – 117Helical; Name=S2 of repeat ISequence analysisAdd BLAST18
Topological domaini118 – 130CytoplasmicSequence analysisAdd BLAST13
Transmembranei131 – 145Helical; Name=S3 of repeat ISequence analysisAdd BLAST15
Topological domaini146 – 157ExtracellularSequence analysisAdd BLAST12
Transmembranei158 – 176Helical; Name=S4 of repeat ISequence analysisAdd BLAST19
Topological domaini177 – 196CytoplasmicSequence analysisAdd BLAST20
Transmembranei197 – 216Helical; Name=S5 of repeat ISequence analysisAdd BLAST20
Topological domaini217 – 302ExtracellularSequence analysisAdd BLAST86
Transmembranei303 – 327Helical; Name=S6 of repeat ISequence analysisAdd BLAST25
Topological domaini328 – 434CytoplasmicSequence analysisAdd BLAST107
Transmembranei435 – 454Helical; Name=S1 of repeat IISequence analysisAdd BLAST20
Topological domaini455 – 467ExtracellularSequence analysisAdd BLAST13
Transmembranei468 – 487Helical; Name=S2 of repeat IISequence analysisAdd BLAST20
Topological domaini488 – 496CytoplasmicSequence analysis9
Transmembranei497 – 515Helical; Name=S3 of repeat IISequence analysisAdd BLAST19
Topological domaini516 – 525ExtracellularSequence analysis10
Transmembranei526 – 544Helical; Name=S4 of repeat IISequence analysisAdd BLAST19
Topological domaini545 – 563CytoplasmicSequence analysisAdd BLAST19
Transmembranei564 – 583Helical; Name=S5 of repeat IISequence analysisAdd BLAST20
Topological domaini584 – 639ExtracellularSequence analysisAdd BLAST56
Transmembranei640 – 664Helical; Name=S6 of repeat IISequence analysisAdd BLAST25
Topological domaini665 – 785CytoplasmicSequence analysisAdd BLAST121
Transmembranei786 – 809Helical; Name=S1 of repeat IIISequence analysisAdd BLAST24
Topological domaini810 – 826ExtracellularSequence analysisAdd BLAST17
Transmembranei827 – 846Helical; Name=S2 of repeat IIISequence analysisAdd BLAST20
Topological domaini847 – 854CytoplasmicSequence analysis8
Transmembranei855 – 877Helical; Name=S3 of repeat IIISequence analysisAdd BLAST23
Topological domaini878 – 885ExtracellularSequence analysis8
Transmembranei886 – 900Helical; Name=S4 of repeat IIISequence analysisAdd BLAST15
Topological domaini901 – 921CytoplasmicSequence analysisAdd BLAST21
Transmembranei922 – 941Helical; Name=S5 of repeat IIISequence analysisAdd BLAST20
Topological domaini942 – 1030ExtracellularSequence analysisAdd BLAST89
Transmembranei1031 – 1055Helical; Name=S6 of repeat IIISequence analysisAdd BLAST25
Topological domaini1056 – 1110CytoplasmicSequence analysisAdd BLAST55
Transmembranei1111 – 1129Helical; Name=S1 of repeat IVSequence analysisAdd BLAST19
Topological domaini1130 – 1143ExtracellularSequence analysisAdd BLAST14
Transmembranei1144 – 1163Helical; Name=S2 of repeat IVSequence analysisAdd BLAST20
Topological domaini1164 – 1172CytoplasmicSequence analysis9
Transmembranei1173 – 1191Helical; Name=S3 of repeat IVSequence analysisAdd BLAST19
Topological domaini1192 – 1219ExtracellularSequence analysisAdd BLAST28
Transmembranei1220 – 1238Helical; Name=S4 of repeat IVSequence analysisAdd BLAST19
Topological domaini1239 – 1257CytoplasmicSequence analysisAdd BLAST19
Transmembranei1258 – 1277Helical; Name=S5 of repeat IVSequence analysisAdd BLAST20
Topological domaini1278 – 1343ExtracellularSequence analysisAdd BLAST66
Transmembranei1344 – 1362Helical; Name=S6 of repeat IVSequence analysisAdd BLAST19
Topological domaini1363 – 1687CytoplasmicSequence analysisAdd BLAST325

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000539611 – 1687Muscle calcium channel subunit alpha-1Add BLAST1687

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi90N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein, Phosphoprotein

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Predominantly expressed in the larval body wall musculature. In adults, highest expression in thorax followed by head and at a lower extent by abdomen.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Late embryonic.

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7370.XP_005191382.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati48 – 330IAdd BLAST283
Repeati420 – 667IIAdd BLAST248
Repeati777 – 1059IIIAdd BLAST283
Repeati1096 – 1370IVAdd BLAST275

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni979 – 1068Dihydropyridine bindingBy similarityAdd BLAST90
Regioni1327 – 1389Dihydropyridine bindingBy similarityAdd BLAST63
Regioni1337 – 1378Phenylalkylamine bindingBy similarityAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi564 – 570Poly-Leu7
Compositional biasi1037 – 1043Poly-Ile7

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Each of the four internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and one positively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterized by a series of positively charged amino acids at every third position.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0017, Eukaryota
KOG2301, Eukaryota

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031649, GPHH_dom
IPR005821, Ion_trans_dom
IPR014873, VDCC_a1su_IQ
IPR005446, VDCC_L_a1su
IPR002077, VDCCAlpha1
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10037, PTHR10037, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08763, Ca_chan_IQ, 1 hit
PF16905, GPHH, 1 hit
PF00520, Ion_trans, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00167, CACHANNEL
PR01630, LVDCCALPHA1

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01062, Ca_chan_IQ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q25452-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDAVCPTET DNVQNKQKAT TPKRTQRRGG KQQLDRPERA LFCLTLKNPL
60 70 80 90 100
RIFCIKIVDS KLFEYFILLT IFANCVALAV YTPYPSGDSN ITNQMLEKIE
110 120 130 140 150
YIFLVIFTSE CVMKIIAYGF VLHTGSYLRN GWNFLDFFIV VIGMISTALS
160 170 180 190 200
NLVKEGFDVK ALRAFRVLRP LRLVSGVPSL QVVLNSILKA MIPLLHIALL
210 220 230 240 250
VLFVIIIYAI IGLELFSGKL HKTCRHSNTG EYLNDLDELH ACGVGFKCPS
260 270 280 290 300
GYECFDDWVG PNDGITNFDN FGLSMLTVFQ CITLEGWTDV LYSIQDAMGS
310 320 330 340 350
SWEWIYFVSM VILGAFFVMN LILGVLSGEF SKERTKAKNR GDFQKLREKQ
360 370 380 390 400
QIEEDLRGYL DWITQAEDIE PDPDAQIIED CHKNKVKEVV SIDNLKDHEN
410 420 430 440 450
ETQQTDSWFR SQKKYLERIN RRIRRACRKA VKSQAFYWLI ILLVFLNTGV
460 470 480 490 500
LATEHYRQPI WLDQFQEYTN IFFIALFTCE MILKMYSLGF QGYFVSLFNR
510 520 530 540 550
FDCFVVIGSI SEMVLTSSEL MAPLGVSVLR CVRLLRVFKV TKYWHSLSNL
560 570 580 590 600
VASLLNSIQS IASLLLLLFL FIVIFGLLGM QVFGGRFTFK PEEEKPRSNF
610 620 630 640 650
DSFYQSLLTV FQILTGEDWN VVMYDGIRAY GGVFSFGIVA CIYYIILFIC
660 670 680 690 700
GNYILLNVFL AIAVDNLADA DSLSTIEKED ESQIQLDNQI KNEMENEEYL
710 720 730 740 750
QNGDHISFKA EFGADLDTYL QDEECGSYSD DENTYNKLGG VKQRVSSLPR
760 770 780 790 800
RNTNTDMDRI KKDIPYGTSF FIFSHTNRFR IFCHRLCNHS NFGNFILCCI
810 820 830 840 850
MFSSAMLAAE NPLKADASRN IVLNKFDYFF TAVFTIELVL KLISYGFVLH
860 870 880 890 900
DGAFCRSAFN LLDLLVVCVS LISIFFNSNA ISVVKILRVL RVLRPLRAIN
910 920 930 940 950
RAKGLKHVVQ CVIVAVKTIG NIVLVTCLLQ FMFAVIGVQL FKGKFFSCSD
960 970 980 990 1000
GSKVYESDCH GTYLFYENGD INKPRLKERE WKNNKFHFDD VAKAMLTLFT
1010 1020 1030 1040 1050
VSTFEGWPTL LYVSIDSNKE NGGPIYNFRP IVAAYYIIYI IIIAFFMVNI
1060 1070 1080 1090 1100
FVGFVIVTFQ NEGEQEYKNC ELDKNQRNCI EFALKAKPVR RYIPKHSIQY
1110 1120 1130 1140 1150
KVWWFVTSSS FEYSIFVLIM INTVTLAMKF YKQPEYYSEI LDALNMIFTA
1160 1170 1180 1190 1200
VFSLEFIFKL AAFRFKNYFG DAWNTFDFII VLGSFIDIVY SEIKTKEQAL
1210 1220 1230 1240 1250
ATCDGQSCNK AKGGSTLISI NFFRLFRVMR LVKLLSKGEG IRTLLWTFIK
1260 1270 1280 1290 1300
SFQALPYVAL LIVMLFFIYA VIGMQVFGKI MLEEGTSIDR NNNFQTFPQA
1310 1320 1330 1340 1350
VLVLFRSATG EAWQEIMMAC SPRDDVKCDP ESDAVNNCGS SIAFPYFISF
1360 1370 1380 1390 1400
YVLCSFLIIN LFVAVIMDNF DYLTRDWSIL GPHHLDEFIR LWSEYDPDAK
1410 1420 1430 1440 1450
GRIKHLDVVT LLRKISPPLG FGKLCPHRMA CKRLVSMNMP LNSDGTVLFN
1460 1470 1480 1490 1500
ATLFAVVRLP LAIKTDGNID EANAELRATI KQIWKRTNPR LLDQVVLTGN
1510 1520 1530 1540 1550
DDEVTVGKFY ATYLIQDYFR RFKKRKEQEG KCDQTENAVT LQAGLRTLQQ
1560 1570 1580 1590 1600
NSPALKRTIS GYLDELASEA DPMHRRHHSL FGKVMSSLLR HEEITSSKIK
1610 1620 1630 1640 1650
HLSRTKTIPY QVEFLQHKVQ LERNKDCLTS ASDDISIEKI IRKQNKYNGQ
1660 1670 1680
YFNSEANFMD NIKYTPRYDG EEYEMEDPKS KDKDEEF
Length:1,687
Mass (Da):193,875
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i628606AFE46DDDEF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z31723 mRNA Translation: CAA83514.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S41742

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z31723 mRNA Translation: CAA83514.1
PIRiS41742

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7370.XP_005191382.1

Organism-specific databases

VEuPathDBiVectorBase:MDOA002080
VectorBase:MDOA005409
VectorBase:MDOA010384
VectorBase:MDOA014412

Phylogenomic databases

eggNOGiKOG0017, Eukaryota
KOG2301, Eukaryota

Family and domain databases

Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR031649, GPHH_dom
IPR005821, Ion_trans_dom
IPR014873, VDCC_a1su_IQ
IPR005446, VDCC_L_a1su
IPR002077, VDCCAlpha1
IPR043203, VGCC_Ca_Na
IPR027359, Volt_channel_dom_sf
PANTHERiPTHR10037, PTHR10037, 2 hits
PfamiView protein in Pfam
PF08763, Ca_chan_IQ, 1 hit
PF16905, GPHH, 1 hit
PF00520, Ion_trans, 4 hits
PRINTSiPR00167, CACHANNEL
PR01630, LVDCCALPHA1
SMARTiView protein in SMART
SM01062, Ca_chan_IQ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCAC1M_MUSDO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q25452
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: February 10, 2021
This is version 101 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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