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Entry version 169 (02 Jun 2021)
Sequence version 2 (15 Mar 2004)
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Protein

Protein dead ringer

Gene

retn

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor which is a downstream target of gcm and repo. Directly or indirectly activates the transcription of locos and pros, which are essential for the development of some glial cells. Plays an essential role in defining the cell shape and migration characteristics of longitudinal glia that enable them to establish a normal axon scaffold.

2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein dead ringer
Alternative name(s):
Protein retained
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:retn
Synonyms:dri
ORF Names:CG5403
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0004795, retn

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Flies show axon guidance abnormalities in mushroom bodies and pathfinding errors by photoreceptor and subesophageal neurons. Female flies with retn defects are strikingly resistant to male courtship and show male-like courtship of females and males, especially as they age.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002005831 – 911Protein dead ringerAdd BLAST911

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei30Phosphoserine1 Publication1
Modified residuei35Phosphothreonine1 Publication1
Modified residuei44Phosphoserine1 Publication1
Modified residuei592Phosphoserine1 Publication1
Modified residuei594Phosphoserine1 Publication1
Modified residuei720Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q24573

PRoteomics IDEntifications database

More...
PRIDEi
Q24573

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q24573

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Present in the pharyngeal muscles, hindgut epithelium, amnioserosa, ring gland, midgut-hindgut junction, posterior region of each brain lobe, longitudinal glial cells of the CNS and the salivary gland duct of germ-band retracted embryos.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed maternally throughout the embryo at the syncytial cleavage divisions and zygotically at the termini and in a broad central band during cellularization. At germ band extension, the protein is found in the mesoderm. Expressed in a subset of neurons from larva and pupa.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
FBgn0004795, Expressed in embryo and 56 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q24573, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q24573, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
70031, 15 interactors

Protein interaction database and analysis system

More...
IntActi
Q24573, 15 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0071982

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1911
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Biological Magnetic Resonance Data Bank

More...
BMRBi
Q24573

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q24573

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q24573

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini293 – 385ARIDPROSITE-ProRule annotationAdd BLAST93
Domaini731 – 825REKLESPROSITE-ProRule annotationAdd BLAST95

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 44DisorderedSequence analysisAdd BLAST44
Regioni67 – 87DisorderedSequence analysisAdd BLAST21
Regioni172 – 274DisorderedSequence analysisAdd BLAST103
Regioni501 – 633DisorderedSequence analysisAdd BLAST133
Regioni662 – 775DisorderedSequence analysisAdd BLAST114
Regioni826 – 877DisorderedSequence analysisAdd BLAST52

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi20 – 44Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi172 – 208Polar residuesSequence analysisAdd BLAST37
Compositional biasi251 – 274Polar residuesSequence analysisAdd BLAST24
Compositional biasi510 – 556Polar residuesSequence analysisAdd BLAST47
Compositional biasi566 – 598Polar residuesSequence analysisAdd BLAST33
Compositional biasi599 – 624Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi685 – 699Polar residuesSequence analysisAdd BLAST15
Compositional biasi700 – 720Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi721 – 741Polar residuesSequence analysisAdd BLAST21
Compositional biasi856 – 873Basic and acidic residuesSequence analysisAdd BLAST18

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2744, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000169348

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q24573

Identification of Orthologs from Complete Genome Data

More...
OMAi
HQLDKSD

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q24573

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR023334, REKLES_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01388, ARID, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00501, BRIGHT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46774, SSF46774, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51011, ARID, 1 hit
PS51486, REKLES, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform B1 Publication (identifier: Q24573-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQLRVHPTMD CSGRSTSNIE RDSDLGDDLS HGDRTDDEMR DCDSVDGEHH
60 70 80 90 100
QLSAKAAIAA RLSHTVSGGG GSFASPEPQT ELPLSHHHQL PPNHPLNALG
110 120 130 140 150
SFMGIGGLHS IPNLQHSDVL EKLKMQVRDM KVGLMEQDYA AAAHAAAFGA
160 170 180 190 200
NMLPTTISSG FPLPHNSVAF GHVTSSPSGG NGSSYNGGTT PTNSSNSNAT
210 220 230 240 250
TNGGGTAGPG GTGGSGGGGG GGGGGGGGVG GHQFSFASPT AAPSGKEARH
260 270 280 290 300
FAANSASNSS TSSEASNSSQ QNNGWSFEEQ FKQVRQLYEI NDDPKRKEFL
310 320 330 340 350
DDLFSFMQKR GTPINRLPIM AKSVLDLYEL YNLVIARGGL VDVINKKLWQ
360 370 380 390 400
EIIKGLHLPS SITSAAFTLR TQYMKYLYPY ECEKKNLSTP AELQAAIDGN
410 420 430 440 450
RREGRRSSYG QYEAMHNQMP MTPISRPSLP GGMQQMSPLA LVTHAAVANN
460 470 480 490 500
QQAQAAAAAA AAHHRLMGAP AFGQMPNLVK QEIESRMMEY LQLIQAKKEQ
510 520 530 540 550
GMPPVLGGNH PHQQQHSQQQ QQQQHHHQQQ QQQQSQQQHH LQQQRQRSQS
560 570 580 590 600
PDLSKHEALS AQVALWHMYH NNNSPPGSAH TSPQQREALN LSDSPPNLTN
610 620 630 640 650
IKREREREPT PEPVDQDDKF VDQPPPAKRV GSGLLPPGFP ANFYLNPHNM
660 670 680 690 700
AAVAAAAGFH HPSMGHQQDA ASEGEPEDDY AHGEHNTTGN SSSMHDDSEP
710 720 730 740 750
QQMNGHHHHQ THHLDKSDDS AIENSPTTST TTGGSVGHRH SSPVSTKKKG
760 770 780 790 800
GAKPQSGGKD VPTEDKDASS SGKLNPLETL SLLSGMQFQV ARNGTGDNGE
810 820 830 840 850
PQLIVNLELN GVKYSGVLVA NVPLSQSETR TSSPCHAEAP TVEEEKDEEE
860 870 880 890 900
EEEPKAAEEE SHRSPVKQEN EDVDQDMEGS EVLLNGGASA VGGAGAGVGV
910
GVPLLKDAVV S
Length:911
Mass (Da):97,365
Last modified:March 15, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A2F0BFAB468906A
GO
Isoform A1 Publication (identifier: Q24573-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     248-252: Missing.

Show »
Length:906
Mass (Da):96,782
Checksum:iAE4B440BA927CC0E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4LGB3A0A0B4LGB3_DROME
Retained, isoform E
retn 2535, BcDNA:LD35748, Dead Ringer, Dmel\CG5403, DRI
654Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4LGF9A0A0B4LGF9_DROME
Retained, isoform C
retn 2535, BcDNA:LD35748, Dead Ringer, Dmel\CG5403, DRI
904Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4LHB8A0A0B4LHB8_DROME
Retained, isoform D
retn 2535, BcDNA:LD35748, Dead Ringer, Dmel\CG5403, DRI
635Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB05771 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti176S → A in AAB05771 (PubMed:8622680).Curated1
Sequence conflicti219G → GA in AAB05771 (PubMed:8622680).Curated1
Sequence conflicti524Missing in AAB05771 (PubMed:8622680).Curated1
Sequence conflicti528Missing in AAB05771 (PubMed:8622680).Curated1
Sequence conflicti761V → L in AAB05771 (PubMed:8622680).Curated1
Sequence conflicti853E → EEE in AAB05771 (PubMed:8622680).Curated1
Sequence conflicti873V → A in AAB05771 (PubMed:8622680).Curated1
Sequence conflicti902V → VGV in AAB05771 (PubMed:8622680).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_050694248 – 252Missing in isoform A. 2 Publications5

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U62542 mRNA Translation: AAB05771.1 Different initiation.
AE013599 Genomic DNA Translation: AAO41347.1
AE013599 Genomic DNA Translation: AAF47037.3
AY118955 mRNA Translation: AAM50815.1

Protein sequence database of the Protein Information Resource

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PIRi
JC6093

NCBI Reference Sequences

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RefSeqi
NP_476864.2, NM_057516.4 [Q24573-2]
NP_788434.1, NM_176254.2 [Q24573-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0072072; FBpp0071981; FBgn0004795 [Q24573-2]
FBtr0072073; FBpp0071982; FBgn0004795 [Q24573-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
45976

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG5403

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62542 mRNA Translation: AAB05771.1 Different initiation.
AE013599 Genomic DNA Translation: AAO41347.1
AE013599 Genomic DNA Translation: AAF47037.3
AY118955 mRNA Translation: AAM50815.1
PIRiJC6093
RefSeqiNP_476864.2, NM_057516.4 [Q24573-2]
NP_788434.1, NM_176254.2 [Q24573-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1C20NMR-A274-401[»]
1KQQNMR-A274-410[»]
BMRBiQ24573
SMRiQ24573
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi70031, 15 interactors
IntActiQ24573, 15 interactors
STRINGi7227.FBpp0071982

PTM databases

iPTMnetiQ24573

Proteomic databases

PaxDbiQ24573
PRIDEiQ24573

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
45976

Genome annotation databases

EnsemblMetazoaiFBtr0072072; FBpp0071981; FBgn0004795 [Q24573-2]
FBtr0072073; FBpp0071982; FBgn0004795 [Q24573-1]
GeneIDi45976
KEGGidme:Dmel_CG5403

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56729
FlyBaseiFBgn0004795, retn

Phylogenomic databases

eggNOGiKOG2744, Eukaryota
GeneTreeiENSGT00940000169348
InParanoidiQ24573
OMAiHQLDKSD
PhylomeDBiQ24573

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
45976, 0 hits in 3 CRISPR screens
EvolutionaryTraceiQ24573

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
45976

Protein Ontology

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PROi
PR:Q24573

Gene expression databases

BgeeiFBgn0004795, Expressed in embryo and 56 other tissues
ExpressionAtlasiQ24573, baseline and differential
GenevisibleiQ24573, DM

Family and domain databases

Gene3Di1.10.150.60, 1 hit
InterProiView protein in InterPro
IPR001606, ARID_dom
IPR036431, ARID_dom_sf
IPR023334, REKLES_domain
PfamiView protein in Pfam
PF01388, ARID, 1 hit
SMARTiView protein in SMART
SM00501, BRIGHT, 1 hit
SUPFAMiSSF46774, SSF46774, 1 hit
PROSITEiView protein in PROSITE
PS51011, ARID, 1 hit
PS51486, REKLES, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDRI_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q24573
Secondary accession number(s): Q8MSB0, Q9W1M0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 15, 2004
Last modified: June 2, 2021
This is version 169 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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