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UniProtKB - Q24206 (BRC4_DROME)

Entry version 197 (10 Feb 2021)
Sequence version 2 (21 Feb 2001)
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Protein

Broad-complex core protein isoform 6

Gene

br

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Broad-complex proteins are required for puffing and transcription of salivary gland late genes during metamorphosis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri710 – 733C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri740 – 763C2H2-type 2PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding
LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q24206

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Broad-complex core protein isoform 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:br
Synonyms:Br-C
ORF Names:CG11491
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0283451, br

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000470701 – 880Broad-complex core protein isoform 6Add BLAST880

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q24206

PRoteomics IDEntifications database

More...PRIDEi		Q24206

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Accumulates to a high level at the beginning of the ecdysone response, during the metamorphosis of imaginal disks in puff stage 1, and abruptly disappears after several hours.1 Publication

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced as a primary response to 20-hydroxyecdysone in third instar larval imaginal disks.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0000210, Expressed in wing disc (Drosophila) and 27 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q24206, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q24206, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		69091, 41 interactors

Database of interacting proteins

More...DIPi		DIP-18557N

Protein interaction database and analysis system

More...IntActi		Q24206, 1 interactor

STRING: functional protein association networks

More...STRINGi		7227.FBpp0289656

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q24206

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini32 – 97BTBPROSITE-ProRule annotationAdd BLAST66

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi203 – 207Poly-Ala5
Compositional biasi265 – 268Poly-Asn4
Compositional biasi458 – 466Poly-Asn9
Compositional biasi584 – 589Poly-Pro6
Compositional biasi618 – 621Poly-Ala4
Compositional biasi798 – 803Poly-Ala6
Compositional biasi821 – 833Poly-AlaAdd BLAST13
Compositional biasi862 – 867Poly-Gln6

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri710 – 733C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri740 – 763C2H2-type 2PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QUP1, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_011721_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q24206

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000210, BTB/POZ_dom
IPR011333, SKP1/BTB/POZ_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00651, BTB, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00225, BTB, 1 hit
SM00355, ZnF_C2H2, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54695, SSF54695, 1 hit
SSF57667, SSF57667, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50097, BTB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (6+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 6 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 6 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 6 (identifier: Q24206-1) [UniParc]FASTAAdd to basket
Also known as: BRCORE-Z4

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDDTQHFCLR WNNYQSSITS AFENLRDDEA FVDVTLACEG RSIKAHRVVL 
        60         70         80         90        100
SACSPYFREL LKSTPCKHPV ILLQDVNFMD LHALVEFIYH GEVNVHQKSL 
       110        120        130        140        150
QSFLKTAEVL RVSGLTQQQA EDTHSHLAQI QNLANSGGRT PLNTHTQSLP 
       160        170        180        190        200
HPHHGSLHDD GGSSTLFSRQ GAGSPPPTAV PSLPSHINNQ LLKRMAMMHR 
       210        220        230        240        250
SSAAAAAEET SHAFKRLRGS DNSLPLSGAV GSGSNNNSPD LPPLHARSAS 
       260        270        280        290        300
PQQTPADFST IKHHNNNNTP PLKEEKRNGP TGNGNSGNGN GNGNGASNGN 
       310        320        330        340        350
GISISDKLGS LTPSPLARAG ADDVKSEPMD MVCSNNNANA NDEHSNDSTG 
       360        370        380        390        400
EHDANRSSSG DGGKGSLSSG NDEEIGDGLA SHHAAPQFIM SPAENKMFHA 
       410        420        430        440        450
AAFNFPNIDP SALLGLNTQL QQSGDLAVSP QGGSTGSLLS GVIVPGGSGG 
       460        470        480        490        500
TPSNSSSNNN NNNSNNQQQK VEQQSSPHQL LQQQHHSTPH TNSPQLKQEQ 
       510        520        530        540        550
PKSGGGSCKS SDLHIAAGSE RSLSRSSQGM PDAGGHSATP SPTAAYHKRE 
       560        570        580        590        600
RERERERERE RERERERSLD HERDLERPGG TGSPPPPPPS HHSHFGQHPL 
       610        620        630        640        650
SLLPSHHQLH ATHHELSAAA AHHAHAHAHA AHAHALARAG SPMEHHHLLH 
       660        670        680        690        700
HRRASLSPSG AVSSASGAGG RGGGAGGPGG PGGSLLSSVR AQDVAQANRL 
       710        720        730        740        750
LLPLPLNACH RCDVCGKLLS TKLTLKRHKE QQHLQPLNNA VCNLCHKVFR 
       760        770        780        790        800
TLNSLNNHKS IYHRRQKNHH SYFHHGAGVS QAGSPGSRLH QSLSSLSAAA 
       810        820        830        840        850
AAANNSVNVG GGSVGGAGGN AVAAAAAAAA AAAELLLSPI VGAAAVAGGT 
       860        870        880
ASSTLQLAAA HQQQQQQSSP GIVKPCMDFL
Length:880
Mass (Da):92,305
Last modified:February 21, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i500C0A4A38663AAF
GO
Isoform 1 (identifier: Q01295-1) [UniParc]FASTAAdd to basket
Also known as: BRCORE-TNT1-Q1-Z1
The sequence of this isoform can be found in the external entry Q01295.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:727
Mass (Da):77,393
GO
Isoform 2 (identifier: Q01295-2) [UniParc]FASTAAdd to basket
Also known as: BRCORE-Q1-Z1
The sequence of this isoform can be found in the external entry Q01295.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:663
Mass (Da):70,534
GO
Isoform 3 (identifier: Q01295-3) [UniParc]FASTAAdd to basket
Also known as: BRCORE-Q2-Z1
The sequence of this isoform can be found in the external entry Q01295.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:680
Mass (Da):72,308
GO
Isoform 4 (identifier: Q01295-4) [UniParc]FASTAAdd to basket
Also known as: BRCORE-Z2
The sequence of this isoform can be found in the external entry Q01295.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:514
Mass (Da):55,459
GO
Isoform 5 (identifier: Q01295-5) [UniParc]FASTAAdd to basket
Also known as: BRCORE-NS-Z3
The sequence of this isoform can be found in the external entry Q01295.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:702
Mass (Da):74,145
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D8FT05D8FT05_DROME
Broad, isoform O
br 2B5, 2Bc, A18, BR, Br
663Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E1JJB2E1JJB2_DROME
Broad, isoform P
br 2B5, 2Bc, A18, BR, Br
1,011Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9W572Q9W572_DROME
Broad, isoform C
br 2B5, 2Bc, A18, BR, Br
880Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8IRX4Q8IRX4_DROME
Broad, isoform J
br 2B5, 2Bc, A18, BR, Br
514Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MSM6M9MSM6_DROME
Broad, isoform M
br 2B5, 2Bc, A18, BR, Br
724Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6H2EEH5A0A6H2EEH5_DROME
Broad, isoform R
br 2B5, 2Bc, A18, BR, Br
644Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB09760 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti436G → D in AAB09760 (PubMed:8660872).Curated1
Sequence conflicti621Missing (PubMed:8660872).Curated1
Sequence conflicti624A → R in AAB09760 (PubMed:8660872).Curated1
Sequence conflicti661 – 662AV → L (PubMed:8660872).Curated2
Sequence conflicti678Missing (PubMed:8660872).Curated1
Sequence conflicti722 – 723KL → NV in AAB09760 (PubMed:8660872).Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U51585 mRNA Translation: AAB09760.1 Frameshift.
AE014298 Genomic DNA Translation: AAF45647.1
AL009146 Genomic DNA Translation: CAA15627.1
AY069756 mRNA Translation: AAL39901.1

NCBI Reference Sequences

More...RefSeqi		NP_001138144.1, NM_001144672.3 [Q24206-1]
NP_001259134.1, NM_001272205.1 [Q24206-1]
NP_726751.2, NM_166895.2 [Q24206-1]
NP_726752.1, NM_166896.3 [Q24206-1]
NP_726753.1, NM_166897.2 [Q24206-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0070261; FBpp0070251; FBgn0283451 [Q24206-1]
FBtr0070263; FBpp0070253; FBgn0283451 [Q24206-1]
FBtr0300427; FBpp0289656; FBgn0283451 [Q24206-1]
FBtr0300428; FBpp0289657; FBgn0283451 [Q24206-1]
FBtr0332293; FBpp0304572; FBgn0283451 [Q24206-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		44505

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG11491

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U51585 mRNA Translation: AAB09760.1 Frameshift.
AE014298 Genomic DNA Translation: AAF45647.1
AL009146 Genomic DNA Translation: CAA15627.1
AY069756 mRNA Translation: AAL39901.1
RefSeqiNP_001138144.1, NM_001144672.3 [Q24206-1]
NP_001259134.1, NM_001272205.1 [Q24206-1]
NP_726751.2, NM_166895.2 [Q24206-1]
NP_726752.1, NM_166896.3 [Q24206-1]
NP_726753.1, NM_166897.2 [Q24206-1]

3D structure databases

SMRiQ24206
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi69091, 41 interactors
DIPiDIP-18557N
IntActiQ24206, 1 interactor
STRINGi7227.FBpp0289656

Proteomic databases

PaxDbiQ24206
PRIDEiQ24206

Genome annotation databases

EnsemblMetazoaiFBtr0070261; FBpp0070251; FBgn0283451 [Q24206-1]
FBtr0070263; FBpp0070253; FBgn0283451 [Q24206-1]
FBtr0300427; FBpp0289656; FBgn0283451 [Q24206-1]
FBtr0300428; FBpp0289657; FBgn0283451 [Q24206-1]
FBtr0332293; FBpp0304572; FBgn0283451 [Q24206-1]
GeneIDi44505
KEGGidme:Dmel_CG11491

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		103946
FlyBaseiFBgn0283451, br

Phylogenomic databases

eggNOGiENOG502QUP1, Eukaryota
HOGENOMiCLU_011721_0_0_1
InParanoidiQ24206

Enzyme and pathway databases

SignaLinkiQ24206

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		44505, 1 hit in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		br, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		44505

Gene expression databases

BgeeiFBgn0000210, Expressed in wing disc (Drosophila) and 27 other tissues
ExpressionAtlasiQ24206, baseline and differential
GenevisibleiQ24206, DM

Family and domain databases

InterProiView protein in InterPro
IPR000210, BTB/POZ_dom
IPR011333, SKP1/BTB/POZ_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00651, BTB, 1 hit
SMARTiView protein in SMART
SM00225, BTB, 1 hit
SM00355, ZnF_C2H2, 2 hits
SUPFAMiSSF54695, SSF54695, 1 hit
SSF57667, SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS50097, BTB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBRC4_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q24206
Secondary accession number(s): O46064, Q9W575
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: February 21, 2001
Last modified: February 10, 2021
This is version 197 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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