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Protein

40S ribosomal protein S5a

Gene

RpS5a

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: FlyBase
  • ribosomal small subunit assembly Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-DME-72649 Translation initiation complex formation
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-DME-72702 Ribosomal scanning and start codon recognition
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S5a
Gene namesi
Name:RpS5a
Synonyms:M(1)15D, RpS5
ORF Names:CG8922
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0002590 RpS5a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001245301 – 22840S ribosomal protein S5aAdd BLAST228

Proteomic databases

PaxDbiQ24186
PRIDEiQ24186

Expressioni

Gene expression databases

BgeeiFBgn0002590
ExpressionAtlasiQ24186 baseline and differential
GenevisibleiQ24186 DM

Interactioni

Protein-protein interaction databases

BioGridi59029, 24 interactors
DIPiDIP-18111N
IntActiQ24186, 6 interactors
STRINGi7227.FBpp0074180

Structurei

3D structure databases

ProteinModelPortaliQ24186
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3291 Eukaryota
COG0049 LUCA
InParanoidiQ24186
KOiK02989
OMAiDSLMMKG
OrthoDBiEOG091G0KXZ
PhylomeDBiQ24186

Family and domain databases

CDDicd14867 uS7_Eukaryote, 1 hit
Gene3Di1.10.455.10, 1 hit
InterProiView protein in InterPro
IPR000235 Ribosomal_S5/S7
IPR005716 Ribosomal_S5/S7_euk/arc
IPR020606 Ribosomal_S7_CS
IPR023798 Ribosomal_S7_dom
IPR036823 Ribosomal_S7_dom_sf
PANTHERiPTHR11205 PTHR11205, 1 hit
PfamiView protein in Pfam
PF00177 Ribosomal_S7, 1 hit
PIRSFiPIRSF002122 RPS7p_RPS7a_RPS5e_RPS7o, 1 hit
SUPFAMiSSF47973 SSF47973, 1 hit
TIGRFAMsiTIGR01028 uS7_euk_arch, 1 hit
PROSITEiView protein in PROSITE
PS00052 RIBOSOMAL_S7, 1 hit

Sequencei

Sequence statusi: Complete.

Q24186-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEVAENVVE TFEEPAAPME AEVAETILET NVVSTTELPE IKLFGRWSCD
60 70 80 90 100
DVTVNDISLQ DYISVKEKFA RYLPHSAGRY AAKRFRKAQC PIVERLTCSL
110 120 130 140 150
MMKGRNNGKK LMACRIVKHS FEIIHLLTGE NPLQILVSAI INSGPREDST
160 170 180 190 200
RIGRAGTVRR QAVDVSPLRR VNQAIWLLCT GAREAAFRNI KTIAECLADE
210 220
LINAAKGSSN SYAIKKKDEL ERVAKSNR
Length:228
Mass (Da):25,434
Last modified:November 1, 1996 - v1
Checksum:i9206E1D8FE470C4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U48394 mRNA Translation: AAB61633.1
AE014298 Genomic DNA Translation: AAF48700.1
AY075368 mRNA Translation: AAL68215.1
RefSeqiNP_001285360.1, NM_001298431.1
NP_001285361.1, NM_001298432.1
NP_001285362.1, NM_001298433.1
NP_523382.1, NM_078658.3
UniGeneiDm.2690

Genome annotation databases

EnsemblMetazoaiFBtr0074406; FBpp0074180; FBgn0002590
FBtr0343292; FBpp0309957; FBgn0002590
FBtr0343293; FBpp0309958; FBgn0002590
FBtr0345132; FBpp0311353; FBgn0002590
GeneIDi32700
KEGGidme:Dmel_CG8922

Similar proteinsi

Entry informationi

Entry nameiRS5A_DROME
AccessioniPrimary (citable) accession number: Q24186
Secondary accession number(s): Q9VX78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: July 18, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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