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Entry version 161 (08 May 2019)
Sequence version 3 (07 Jun 2005)
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Protein

Serine/threonine-protein kinase mig-15

Gene

mig-15

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in cell migration and signal transduction (PubMed:11967148, PubMed:22732572). Important in several developmental processes including epidermal development, Q neuroblast migrations and muscle arm targeting. Required with ina-1/pat-3 to stabilize the commissural axons growth cone along a precise direction and are required for the cell to respond appropriately when signaling in the growth cone must change (PubMed:11967148). During gonad morphogenesis, involved in distal tip cell (DTC) migration from the dorsal side of the hermaphrodite body to the midbody to allow for formation of gonad arms (PubMed:22732572).2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei50ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei151Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi27 – 35ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transducer, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-2559580 Oxidative Stress Induced Senescence

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q23356

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine/threonine-protein kinase mig-15 (EC:2.7.11.1)
Alternative name(s):
Abnormal cell migration protein 15
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mig-15
ORF Names:ZC504.4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
ZC504.4a ; CE25672 ; WBGene00003247 ; mig-15
ZC504.4b ; CE25673 ; WBGene00003247 ; mig-15
ZC504.4c ; CE28273 ; WBGene00003247 ; mig-15
ZC504.4d ; CE32767 ; WBGene00003247 ; mig-15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mutants exhibit premature branching of commissures (PubMed:11967148). RNAi-mediated knockdown results in gonad distal tip cell (DTC) migration defects whereby DTCs do not migrate to the midbody of the hermaphrodite and as a consequence this leads to abnormal gonadal arm formation during gonad morphogenesis (PubMed:22732572). Double knockdown with mig-38 results in enhanced gonad DTC migration defects (PubMed:22732572).2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000863261 – 1096Serine/threonine-protein kinase mig-15Add BLAST1096

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q23356

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q23356

PeptideAtlas

More...
PeptideAtlasi
Q23356

PRoteomics IDEntifications database

More...
PRIDEi
Q23356

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00003247 Expressed in 5 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
46161, 18 interactors

Database of interacting proteins

More...
DIPi
DIP-25874N

Protein interaction database and analysis system

More...
IntActi
Q23356, 7 interactors

STRING: functional protein association networks

More...
STRINGi
6239.ZC504.4c

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q23356

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini21 – 288Protein kinasePROSITE-ProRule annotationAdd BLAST268
Domaini778 – 1070CNHPROSITE-ProRule annotationAdd BLAST293

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0587 Eukaryota
ENOG410XPHR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183196

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q23356

KEGG Orthology (KO)

More...
KOi
K08840

Identification of Orthologs from Complete Genome Data

More...
OMAi
FKIVRYE

Database of Orthologous Groups

More...
OrthoDBi
533537at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q23356

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001180 CNH_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00780 CNH, 1 hit
PF00069 Pkinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00036 CNH, 1 hit
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50219 CNH, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform c (identifier: Q23356-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSSGLDEID LNSLRDPAGI FELIEVVGNG TYGQVYKGRH VKTAQLAAIK
60 70 80 90 100
IMNINEDEED EIKLEINMLK KHSHHRNVAT YYGAFIKKLP SSTGKHDQLW
110 120 130 140 150
LVMEFCGSGS ITDLVKNTKG GSLKEEWIAY ICREILRGLY HLHQSKVIHR
160 170 180 190 200
DIKGQNVLLT DSAEVKLVDF GVSAQLDKTV GRRNTFIGTP YWMAPEVIAC
210 220 230 240 250
DESPEATYDS RSDLWSLGIT ALEMAEGHPP LCDMHPMRAL FLIPRNPPPK
260 270 280 290 300
LKRNKKWTKK FETFIETVLV KDYHQRPYTG ALLRHPFIKE QPHEQTIRHS
310 320 330 340 350
IKEHIDRNRR VKKDDADYEY SGSEDDEPSP NNRGPSMGIR DDSESSSMIP
360 370 380 390 400
MDNTLRKGFQ KLQESSRGFA EPGAQQLRRL PQQPAPAPFQ YQQSRYVEPR
410 420 430 440 450
RESSEVKLRA VSSRGAADGP RHSPASRPRP VSHHQRSPQQ SHPAAPHLAD
460 470 480 490 500
LANYEKRRRS EREERRERER QAHHAMPIAR VSASVPAPQQ SRKMSEPLLI
510 520 530 540 550
THVKPEDLDV LASELSKMGG HHNGRSREES MSPPPPAPPP REASISSITD
560 570 580 590 600
TIDVGELDNG ADAEWDDLKD IMMNGEGTLR GPNKPLPPTP TDGENTLVSD
610 620 630 640 650
VRRNGNGNSG HGAYKGKKIP EIRPGIISLD DDDSDSDNEE GNEPLMFKPI
660 670 680 690 700
NASSSRGALP DLLPKSPQLR RQINDQTRQM SDDRADESAS LFGSFYQPNG
710 720 730 740 750
FQNSDSRSSI QHSFSNRDRE KSFVGYFGGG AGAGGGTVNR PGRPQDINQV
760 770 780 790 800
QVNVTPNSNG TPAENDAPEI RKYKKKFSGE ILCAALWGVN LLIGTDSGLM
810 820 830 840 850
LLDRSGQGKV YPLISRRRFD QMTVLEGQNI LATISGRKRR IRVYYLSWLR
860 870 880 890 900
QKILRTEGAG SANTTEKRNG WVNVGDLQGA IHFKIVRYER IKFLVVGLES
910 920 930 940 950
SIEIYAWAPK PYHKFMSFKS FGSLSHVPLI VDLTVEDNAR LKVLYGSTGG
960 970 980 990 1000
FHAIDLDSAA VYDIYTPAQS GQTTTPHCIV VLPNSNGMQL LLCYDNEGVY
1010 1020 1030 1040 1050
VNTYGRMTKN VVLQWGEMPS SVAYISTGQI MGWGNKAIEI RSVDTGHLDG
1060 1070 1080 1090
VFMHKKAQKL KFLCERNDKV FFSSAKGGGS CQIYFMTLNK PGLTNW
Length:1,096
Mass (Da):122,504
Last modified:June 7, 2005 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC411C11566596386
GO
Isoform a (identifier: Q23356-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     688-696: Missing.

Show »
Length:1,087
Mass (Da):121,544
Checksum:i49FC2C39893F95CD
GO
Isoform b (identifier: Q23356-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     431-435: Missing.
     688-696: Missing.

Note: No experimental confirmation available.
Show »
Length:1,082
Mass (Da):120,956
Checksum:i1648360B61368036
GO
Isoform d (identifier: Q23356-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     356-371: RKGFQKLQESSRGFAE → Q
     688-696: Missing.

Note: No experimental confirmation available.
Show »
Length:1,072
Mass (Da):119,822
Checksum:i1D37093F759D40D0
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_014010356 – 371RKGFQ…RGFAE → Q in isoform d. CuratedAdd BLAST16
Alternative sequenceiVSP_014011431 – 435Missing in isoform b. Curated5
Alternative sequenceiVSP_014012688 – 696Missing in isoform a, isoform b and isoform d. 1 Publication9

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF087131 mRNA Translation: AAD14593.1
AF087132 mRNA Translation: AAD14594.1
AF087133 mRNA Translation: AAD14595.1
Z50029 Genomic DNA Translation: CAB63416.1
Z50029 Genomic DNA Translation: CAB63417.1
Z50029 Genomic DNA Translation: CAC42384.1
Z50029 Genomic DNA Translation: CAD57714.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T27622
T43630
T43632

NCBI Reference Sequences

More...
RefSeqi
NP_001024971.1, NM_001029800.2 [Q23356-2]
NP_001024972.1, NM_001029801.3 [Q23356-3]
NP_001024973.1, NM_001029802.3 [Q23356-1]
NP_001024974.1, NM_001029803.3 [Q23356-4]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
ZC504.4a; ZC504.4a; WBGene00003247 [Q23356-2]
ZC504.4b; ZC504.4b; WBGene00003247 [Q23356-3]
ZC504.4c; ZC504.4c; WBGene00003247 [Q23356-1]
ZC504.4d; ZC504.4d; WBGene00003247 [Q23356-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181248

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_ZC504.4

UCSC genome browser

More...
UCSCi
ZC504.4c c. elegans [Q23356-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF087131 mRNA Translation: AAD14593.1
AF087132 mRNA Translation: AAD14594.1
AF087133 mRNA Translation: AAD14595.1
Z50029 Genomic DNA Translation: CAB63416.1
Z50029 Genomic DNA Translation: CAB63417.1
Z50029 Genomic DNA Translation: CAC42384.1
Z50029 Genomic DNA Translation: CAD57714.1
PIRiT27622
T43630
T43632
RefSeqiNP_001024971.1, NM_001029800.2 [Q23356-2]
NP_001024972.1, NM_001029801.3 [Q23356-3]
NP_001024973.1, NM_001029802.3 [Q23356-1]
NP_001024974.1, NM_001029803.3 [Q23356-4]

3D structure databases

SMRiQ23356
ModBaseiSearch...

Protein-protein interaction databases

BioGridi46161, 18 interactors
DIPiDIP-25874N
IntActiQ23356, 7 interactors
STRINGi6239.ZC504.4c

Proteomic databases

EPDiQ23356
PaxDbiQ23356
PeptideAtlasiQ23356
PRIDEiQ23356

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZC504.4a; ZC504.4a; WBGene00003247 [Q23356-2]
ZC504.4b; ZC504.4b; WBGene00003247 [Q23356-3]
ZC504.4c; ZC504.4c; WBGene00003247 [Q23356-1]
ZC504.4d; ZC504.4d; WBGene00003247 [Q23356-4]
GeneIDi181248
KEGGicel:CELE_ZC504.4
UCSCiZC504.4c c. elegans [Q23356-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181248
WormBaseiZC504.4a ; CE25672 ; WBGene00003247 ; mig-15
ZC504.4b ; CE25673 ; WBGene00003247 ; mig-15
ZC504.4c ; CE28273 ; WBGene00003247 ; mig-15
ZC504.4d ; CE32767 ; WBGene00003247 ; mig-15

Phylogenomic databases

eggNOGiKOG0587 Eukaryota
ENOG410XPHR LUCA
GeneTreeiENSGT00950000183196
InParanoidiQ23356
KOiK08840
OMAiFKIVRYE
OrthoDBi533537at2759
PhylomeDBiQ23356

Enzyme and pathway databases

ReactomeiR-CEL-2559580 Oxidative Stress Induced Senescence
SignaLinkiQ23356

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q23356

Gene expression databases

BgeeiWBGene00003247 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

InterProiView protein in InterPro
IPR001180 CNH_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00780 CNH, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00036 CNH, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50219 CNH, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMIG15_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q23356
Secondary accession number(s): Q8I4B5
, Q8T8M3, Q95ZI7, Q9UAN7, Q9XYC3, Q9XYC4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 7, 2005
Last modified: May 8, 2019
This is version 161 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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