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Entry version 126 (02 Jun 2021)
Sequence version 1 (01 Nov 1996)
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Protein

XO lethal protein 1

Gene

xol-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sex-determining factor that is required for sexual differentiation and X chromosome dosage compensation to promote male development (PubMed:7813020, PubMed:9217163, PubMed:33372658).

High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development. Although related to GHMP kinase, its mode of action remains unclear.

4 Publications

Caution

Although clearly related the GHMP kinase family as demonstrated by the 3D-structure, it lacks many conserved feature of GHMP kinases and probably does not bind ATP, suggesting that it probably does not have kinase activity.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
XO lethal protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:xol-1Imported
ORF Names:C18A11.5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C18A11.5b ; CE35709 ; WBGene00006962 ; xol-1
C18A11.5c ; CE24807 ; WBGene00006962 ; xol-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Worms are XO-lethal, due to inappropriate activating dosage compensation where only 1 X chromosome is present. In contrast xol-1 overexpression is XX-lethal, deactivating the dosage compensation pathway and elevating the expression of X chromosome genes to lethal levels in hermaphrodites.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001566731 – 417XO lethal protein 1Add BLAST417

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q23229

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Specifically expressed at high levels in pre-comma stage XO embryos. Also present at low levels throughout other larval stages in XO animals, but are nearly undetectable in XX larvae and adults of both sexes.1 Publication
Most abundant in male embryos (PubMed:33372658). Expressed at low levels in hermaphrodite embryos (PubMed:33372658).1 Publication

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Down-regulated by at least 4 X-linked genes, termed X-signal elements including fox-1 and sex-1 (PubMed:9217163). High levels of xol-1 in males correlate with low sdc-2 expression, preventing dosage compensation. Conversely, low levels of xol-1 in hermaphrodites correlate with high sdc-2 expression and the assembly of the dosage compensation complex on the X chromosome.4 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00006962, Expressed in multi-cellular organism and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.C18A11.5c

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1417
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q23229

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q23229

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni373 – 417DisorderedSequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi388 – 417Acidic residuesSequence analysisAdd BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GHMP kinase family. Xol-1 subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502TITU, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_659271_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q23229

Identification of Orthologs from Complete Genome Data

More...
OMAi
MEEDSIW

Database of Orthologous Groups

More...
OrthoDBi
1822677at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.230.10, 1 hit
3.30.70.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036554, GHMP_kinase_C_sf
IPR020568, Ribosomal_S5_D2-typ_fold
IPR014721, Ribosomal_S5_D2-typ_fold_subgr
IPR015193, Xol-1_GHMP-like
IPR037087, Xol-1_GHMP-like_sf
IPR015192, Xol-1_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09109, Xol-1_GHMP-like, 1 hit
PF09108, Xol-1_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54211, SSF54211, 1 hit
SSF55060, SSF55060, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform bImported (identifier: Q23229-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQVEANSERR VKILGIDRSE NSPVLTYMET EDDPNFRNSK LAAAPHTVHM
60 70 80 90 100
MDSGFLAINR QCLVKGKAIL AREPKSSNEH MIDDLPKHAH DQHTLSILRD
110 120 130 140 150
FIDQLKLHNV YEINFYDPLD SSGKLAVIPM LIALWKCMLA SETDICDQEV
160 170 180 190 200
LKSIMNSVIA KFELQIPCKN AVIDATLSGS REEVHIIAED GSLENSNGTT
210 220 230 240 250
EHFNKKHDLV FVKTDLHPED FTPQMFPSQA KAKLLRDAFN NEEDEDTFPD
260 270 280 290 300
ILVPAYMTAH SKNRVRQEDY TCLEVEFDSQ VALEKLMNEH EQVEGFEVQQ
310 320 330 340 350
GGILVALKKD SFFDDELIEK IAIAIATESR QSVSSVSFDL LKLGPGASLV
360 370 380 390 400
TLANSRRFEP ECRVVLQIEV KPVSPGETSS EGISDEHHYE EYDEDDIMEE
410
EEAPSARQDD TYDEDEE
Note: Only functional isoform (PubMed:33372658). Produced by alternative splicing of intron 6 which results in the deletion of intron 6 and retention of exon 7 coding sequences (PubMed:33372658).1 Publication
Length:417
Mass (Da):47,159
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i364FE008D91C8662
GO
Isoform cImported (identifier: Q23229-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     323-417: IAIATESRQS...QDDTYDEDEE → YSAQYYLSMT...NKIFAIKQFS

Note: Inactive isoform (PubMed:7813020, PubMed:33372658). Produced by alternative splicing of intron 6 which results in the retention of intron 6 and deletion of exon 7 coding sequences (PubMed:33372658). An in-frame UAA stop codon within intron 6 prematurely terminates translation (PubMed:7813020). Intron 6 retention and exon 7 deletion can also be due to use of an alternative 3' splice acceptor site in the 3'UTR resulting in trans-splicing to the transcripts of unrelated genes (PubMed:33372658).2 Publications
Show »
Length:426
Mass (Da):48,423
Checksum:i90CC20EF32512EC0
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA67048 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti323 – 417IAIAT…DEDEE → VSYHIICYFHINCMFDKTLF TKIFCSHIVFTSR in AAA67048 (PubMed:7813020).CuratedAdd BLAST95

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016414323 – 417IAIAT…DEDEE → YSAQYYLSMTHFSNRISIPL FSSLVFLTVSIVINAMCHKS IFCKRVISRLPFPHCQILKL SHFSTGRTFLSYLSIIAKCT PISHINQSNILPAQNKIFAI KQFS in isoform c. CuratedAdd BLAST95

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L35129 Genomic DNA Translation: AAA67048.1 Sequence problems.
L35129 Genomic DNA Translation: AAA67049.1
L35129 Genomic DNA Translation: AAA67047.1
BX284606 Genomic DNA Translation: CCD65063.1
BX284606 Genomic DNA Translation: CCD65064.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A55473
B55473
C55473
F89581

NCBI Reference Sequences

More...
RefSeqi
NP_001024418.1, NM_001029247.1 [Q23229-1]
NP_001024419.1, NM_001029248.1 [Q23229-3]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C18A11.5b.1; C18A11.5b.1; WBGene00006962 [Q23229-1]
C18A11.5c.1; C18A11.5c.1; WBGene00006962 [Q23229-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181061

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C18A11.5

UCSC genome browser

More...
UCSCi
C18A11.5c, c. elegans [Q23229-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L35129 Genomic DNA Translation: AAA67048.1 Sequence problems.
L35129 Genomic DNA Translation: AAA67049.1
L35129 Genomic DNA Translation: AAA67047.1
BX284606 Genomic DNA Translation: CCD65063.1
BX284606 Genomic DNA Translation: CCD65064.1
PIRiA55473
B55473
C55473
F89581
RefSeqiNP_001024418.1, NM_001029247.1 [Q23229-1]
NP_001024419.1, NM_001029248.1 [Q23229-3]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MG7X-ray1.55A/B1-417[»]
SMRiQ23229
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi6239.C18A11.5c

Proteomic databases

PaxDbiQ23229

Genome annotation databases

EnsemblMetazoaiC18A11.5b.1; C18A11.5b.1; WBGene00006962 [Q23229-1]
C18A11.5c.1; C18A11.5c.1; WBGene00006962 [Q23229-3]
GeneIDi181061
KEGGicel:CELE_C18A11.5
UCSCiC18A11.5c, c. elegans [Q23229-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181061
WormBaseiC18A11.5b ; CE35709 ; WBGene00006962 ; xol-1
C18A11.5c ; CE24807 ; WBGene00006962 ; xol-1

Phylogenomic databases

eggNOGiENOG502TITU, Eukaryota
HOGENOMiCLU_659271_0_0_1
InParanoidiQ23229
OMAiMEEDSIW
OrthoDBi1822677at2759

Miscellaneous databases

EvolutionaryTraceiQ23229

Protein Ontology

More...
PROi
PR:Q23229

Gene expression databases

BgeeiWBGene00006962, Expressed in multi-cellular organism and 4 other tissues

Family and domain databases

Gene3Di3.30.230.10, 1 hit
3.30.70.1000, 1 hit
InterProiView protein in InterPro
IPR036554, GHMP_kinase_C_sf
IPR020568, Ribosomal_S5_D2-typ_fold
IPR014721, Ribosomal_S5_D2-typ_fold_subgr
IPR015193, Xol-1_GHMP-like
IPR037087, Xol-1_GHMP-like_sf
IPR015192, Xol-1_N
PfamiView protein in Pfam
PF09109, Xol-1_GHMP-like, 1 hit
PF09108, Xol-1_N, 1 hit
SUPFAMiSSF54211, SSF54211, 1 hit
SSF55060, SSF55060, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiXOL1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q23229
Secondary accession number(s): Q18064
, Q23230, Q23231, Q7JP92
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: November 1, 1996
Last modified: June 2, 2021
This is version 126 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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