Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 147 (18 Sep 2019)
Sequence version 2 (01 Oct 2001)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Transcription factor egl-13

Gene

egl-13

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transcription factor that is required for uterine cell fate decisions (PubMed:9834196, PubMed:14668410). Controls genes required for the specification and differentiation of O2 and CO2-sensing neurons and for maintaining URX sensory neuronal cell fate (PubMed:23671427).3 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi329 – 397HMG boxPROSITE-ProRule annotationAdd BLAST69

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • DNA-binding transcription factor activity, RNA polymerase II-specific Source: WormBase

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processDifferentiation, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-3769402 Deactivation of the beta-catenin transactivating complex

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription factor egl-131 Publication
Alternative name(s):
Protein egg laying defective 13Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:egl-13Imported
Synonyms:cog-2Imported
ORF Names:T22B7.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
T22B7.1a ; CE28487 ; WBGene00001182 ; egl-13
T22B7.1b ; CE33702 ; WBGene00001182 ; egl-13
T22B7.1c ; CE38552 ; WBGene00001182 ; egl-13
T22B7.1d ; CE05030 ; WBGene00001182 ; egl-13

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Hermaphrodites have an egg laying defective phenotype and a reduced brood size (PubMed:9834196). They display a protruding vulva phenotype and there is a failure of anchor cells to fuse to uterine seam cells (anchor cell-block) (PubMed:9834196). Animals also have defective vulval morphogenesis and gonad migration with increased pi cell divisions, which thus leads to an improper uterine-vulval connection (PubMed:9834196, PubMed:14668410). Defective response to CO2 sensing (PubMed:23671427).2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi331R → K in ty7; egg laying defective phenotype. 1 Publication1
Mutagenesisi335A → T in ku207; egg laying defective phenotype. 1 Publication1
Mutagenesisi364G → E in rp26; egg laying defective phenotype. 1 Publication1
Mutagenesisi394P → L in n483; increased uterine cell divisions. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004328581 – 470Transcription factor egl-13CuratedAdd BLAST470

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q23045

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q23045

PeptideAtlas

More...
PeptideAtlasi
Q23045

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in body wall muscle and head and tail neurons (PubMed:9834196). Specifically expressed in O2 and CO2-sensing neurons, including BAG and URX sensory neurons (PubMed:23671427).2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed following fertilization and during embryogenesis in four neuronal cells (PubMed:23671427). Expressed in BAG, URX, AQR and PQR sensory neurons and cells in the head and tail in L1 larval stage and in the body wall muscle and vulval cells later in larval development (PubMed:23671427). Expressed in cells of the pi uterine cell lineage from late L3 to mid L4 (PubMed:9834196).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00001182 Expressed in 4 organ(s), highest expression level in material anatomical entity

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q23045 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q23045, 73 interactors

STRING: functional protein association networks

More...
STRINGi
6239.T22B7.1a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q23045

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi177 – 182Poly-GlnSequence analysis6

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0528 Eukaryota
ENOG410YZNG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000170160

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000020384

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q23045

Identification of Orthologs from Complete Genome Data

More...
OMAi
LAQTEHG

Database of Orthologous Groups

More...
OrthoDBi
1641977at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.30.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00505 HMG_box, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00398 HMG, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47095 SSF47095, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform aImported (identifier: Q23045-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSRRRKANPT KLSENAKKLA KEVENSQEEN DCDMLAKPQT PTIIIPGHMD
60 70 80 90 100
DTPNPAGSPH DASIKSSSST ISDHTSTSAT TGISDFPDIL AQTEHGCSVL
110 120 130 140 150
IDGNHLREII NSVDTQDGKQ DLLSDVIRQL TSIKERLTND ESPVKDDLKE
160 170 180 190 200
DPDDMSPMLH AGNFDSEMLL RQHELMQHQQ QQMIIANMLK ATQSLPLLFN
210 220 230 240 250
GGLNYEAILN NPVLNATIAG HLPNPLASNI SLLQKSISAK LAAAGNMQTV
260 270 280 290 300
EKVETPLNLS KDTPSPTAIP QSPLSGFRLP YSLGTNYGSD GQLFNNCSPN
310 320 330 340 350
SSGKSTPGNT SVTSEVATPR PQAKSPNHIK RPMNAFMVWA RDERRKILKA
360 370 380 390 400
YPDMHNSNIS KILGSRWKGM SNSEKQPYYE EQSRLSKLHM EQHPDYRYRP
410 420 430 440 450
RPKRTCVIDG KKVRVNEYKT IMKTKKDLMW GDEPGFSQPS DLQMDLASHV
460 470
NLLNDLTQHH HQSHLLQTAE
Length:470
Mass (Da):52,276
Last modified:October 1, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0D8A5DFF8E51C63E
GO
Isoform bImported (identifier: Q23045-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-154: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:316
Mass (Da):35,474
Checksum:i1F301FEF69871D32
GO
Isoform cImported (identifier: Q23045-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-48: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:422
Mass (Da):46,875
Checksum:i77BC731FB12C11C6
GO
Isoform dImported (identifier: Q23045-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-157: MSRRRKANPT...LKEDPDDMSP → MWPMVQ

Show »
Length:319
Mass (Da):35,932
Checksum:i57F13CE3C6104C9D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1C3NSN7A0A1C3NSN7_CAEEL
HMG box domain-containing protein
egl-13 CELE_T22B7.1, T22B7.1
313Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1C3NSN8A0A1C3NSN8_CAEEL
HMG box domain-containing protein
egl-13 CELE_T22B7.1, T22B7.1
438Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0576201 – 157MSRRR…DDMSP → MWPMVQ in isoform d. CuratedAdd BLAST157
Alternative sequenceiVSP_0576211 – 154Missing in isoform b. CuratedAdd BLAST154
Alternative sequenceiVSP_0576221 – 48Missing in isoform c. CuratedAdd BLAST48

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF097319 mRNA Translation: AAD12252.1
FO081738 Genomic DNA Translation: CCD74407.1
FO081738 Genomic DNA Translation: CCD74408.1
FO081738 Genomic DNA Translation: CCD74409.1
FO081738 Genomic DNA Translation: CCD74410.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T25909
T43675

NCBI Reference Sequences

More...
RefSeqi
NP_001024918.1, NM_001029747.3 [Q23045-1]
NP_001024920.1, NM_001029749.3 [Q23045-3]
NP_001294841.1, NM_001307912.1 [Q23045-2]
NP_001294842.1, NM_001307913.1 [Q23045-4]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
T22B7.1a.1; T22B7.1a.1; WBGene00001182 [Q23045-1]
T22B7.1a.2; T22B7.1a.2; WBGene00001182 [Q23045-1]
T22B7.1b.1; T22B7.1b.1; WBGene00001182 [Q23045-2]
T22B7.1c.1; T22B7.1c.1; WBGene00001182 [Q23045-3]
T22B7.1d.1; T22B7.1d.1; WBGene00001182 [Q23045-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
180833

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_T22B7.1

UCSC genome browser

More...
UCSCi
T22B7.1c.2 c. elegans

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF097319 mRNA Translation: AAD12252.1
FO081738 Genomic DNA Translation: CCD74407.1
FO081738 Genomic DNA Translation: CCD74408.1
FO081738 Genomic DNA Translation: CCD74409.1
FO081738 Genomic DNA Translation: CCD74410.1
PIRiT25909
T43675
RefSeqiNP_001024918.1, NM_001029747.3 [Q23045-1]
NP_001024920.1, NM_001029749.3 [Q23045-3]
NP_001294841.1, NM_001307912.1 [Q23045-2]
NP_001294842.1, NM_001307913.1 [Q23045-4]

3D structure databases

SMRiQ23045
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ23045, 73 interactors
STRINGi6239.T22B7.1a

Proteomic databases

EPDiQ23045
PaxDbiQ23045
PeptideAtlasiQ23045

Genome annotation databases

EnsemblMetazoaiT22B7.1a.1; T22B7.1a.1; WBGene00001182 [Q23045-1]
T22B7.1a.2; T22B7.1a.2; WBGene00001182 [Q23045-1]
T22B7.1b.1; T22B7.1b.1; WBGene00001182 [Q23045-2]
T22B7.1c.1; T22B7.1c.1; WBGene00001182 [Q23045-3]
T22B7.1d.1; T22B7.1d.1; WBGene00001182 [Q23045-4]
GeneIDi180833
KEGGicel:CELE_T22B7.1
UCSCiT22B7.1c.2 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
180833
WormBaseiT22B7.1a ; CE28487 ; WBGene00001182 ; egl-13
T22B7.1b ; CE33702 ; WBGene00001182 ; egl-13
T22B7.1c ; CE38552 ; WBGene00001182 ; egl-13
T22B7.1d ; CE05030 ; WBGene00001182 ; egl-13

Phylogenomic databases

eggNOGiKOG0528 Eukaryota
ENOG410YZNG LUCA
GeneTreeiENSGT00940000170160
HOGENOMiHOG000020384
InParanoidiQ23045
OMAiLAQTEHG
OrthoDBi1641977at2759

Enzyme and pathway databases

ReactomeiR-CEL-3769402 Deactivation of the beta-catenin transactivating complex

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q23045

Gene expression databases

BgeeiWBGene00001182 Expressed in 4 organ(s), highest expression level in material anatomical entity
ExpressionAtlasiQ23045 baseline and differential

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEGL13_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q23045
Secondary accession number(s): H2L0M3
, Q4PIT4, Q86G49, Q9TZN5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2015
Last sequence update: October 1, 2001
Last modified: September 18, 2019
This is version 147 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again