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Protein
Submitted name:

Cation channel family protein

Gene

TTHERM_01277520

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelSAAS annotation
Biological processIon transport, Transport
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Cation channel family proteinImported
Gene namesi
ORF Names:TTHERM_01277520Imported
OrganismiTetrahymena thermophila (strain SB210)Imported
Taxonomic identifieri312017 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
Proteomesi
  • UP000009168 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei374 – 393HelicalSequence analysisAdd BLAST20
Transmembranei414 – 434HelicalSequence analysisAdd BLAST21
Transmembranei446 – 470HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi5911.EAR82176

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini553 – 659Cyclic nucleotide-bindingInterPro annotationAdd BLAST107
Domaini689 – 704CCHC-typeInterPro annotationAdd BLAST16

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili737 – 764Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

InParanoidiQ22A56

Family and domain databases

CDDicd00038 CAP_ED, 1 hit
Gene3Di2.60.120.10, 1 hit
InterProiView protein in InterPro
IPR018490 cNMP-bd-like
IPR000595 cNMP-bd_dom
IPR005821 Ion_trans_dom
IPR014710 RmlC-like_jellyroll
IPR001878 Znf_CCHC
PfamiView protein in Pfam
PF00027 cNMP_binding, 1 hit
PF00520 Ion_trans, 1 hit
SMARTiView protein in SMART
SM00100 cNMP, 1 hit
SUPFAMiSSF51206 SSF51206, 1 hit
PROSITEiView protein in PROSITE
PS50042 CNMP_BINDING_3, 1 hit
PS50158 ZF_CCHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q22A56-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQKLEIQNN SKSKKLSVFY KQVPTEQDSS ILEINEEQNE MGKFNNIFQI
60 70 80 90 100
RNSQPQRFHE GDQDNSCNSF KAEINDILQG SQNNVNTANQ SICKMLQEEK
110 120 130 140 150
VEEEEVQITF QDYLIDQRKS IQSQSKNNYT DKEAIKMNIN VNQNSPSSDF
160 170 180 190 200
QEAKVILEQN SSSQRKIIND NSLNRNDEDQ SNCFLSKNTI IKSGTKNQPS
210 220 230 240 250
QNTSQSKSIS QSNQNINNSH ILIQDDIFYE KDIKKLGTKV NFALQNQNQF
260 270 280 290 300
QQDFNATKIY KQNLQKAAKI VSRLLNSSMN RIMRVRQYAI CKTVSYLYAK
310 320 330 340 350
QFNKNCVSMF MLGYKIIYSN ELVIYDLKQS VFALGLNSLI FLKANGISSK
360 370 380 390 400
KKRFDYVFTL TENQKHICKL INQLATVITV AHLAAIGWYF VGVQEANNNQ
410 420 430 440 450
TNWLEKIGIQ SNSIYQQYIY AIYWSITTMT TVGYGDISAA NSVEALYISI
460 470 480 490 500
TMILFSCVFA YSINNIGFIL QEIEKSSKQL NDDLSTIQRY LIRKNVSIQL
510 520 530 540 550
KSRVRHYLSF LAQEQKDRDK QQEDKILSGL SNKLRNEITL EINSKILNNQ
560 570 580 590 600
NLFSSNFSKS TLNKLIFIMK EILVNPNEII ISEDQQDDSS IYFIQSGIIE
610 620 630 640 650
IYQQQIQKKG QISVIKTLTD GQIFGDISFF SGLQRQSSAR SINLSTLYKI
660 670 680 690 700
SRDEFIEILK ENKEDFERFK MMEDQIIFQK EKSVIHNDCY YCKDSNHIAN
710 720 730 740 750
QCPRTHKLFD KQFVVLKHNF SMFQERSQNQ KANQKRKQNA RQNFKKIQDT
760 770 780 790 800
IDCLKQNLES ENCESFFFFD ENLLSSNETM SQYENDEDEE DDTQSDISNN
810 820 830 840 850
CLEEDQNQKK SMKGSVKERI DKSSKNILKS QKSYQTNNDE TEQQFNQDHQ
860 870 880 890 900
LYSNLVYESQ DIPKTILNIV GQSFEASDSI NSNNQEESSK NIFIRQRSQQ
910 920 930 940 950
ESNAVLCEKG RDSLQRTKSE IQQKTIYQKE NEGSDQSNSK ILELLRTRQN
960 970 980 990 1000
SINSTNIQQV DQQKQQIKKR SKKSSHKTSS QYKEDQPQHY HQENSQAQQS
1010 1020 1030 1040 1050
LKSESNKKTS ITCHQSQSHK NSFSKSLKLL NQSQKELRYS VDQQIQNIAA
1060 1070 1080 1090 1100
LMFLHNKNIS SQQINNVNYN YSYQQNSSKC DSSKSSIKDL KEQSLISKKC
1110 1120 1130 1140 1150
NRLSHNQENS QNNLLKQQSI GKNKKQTSNN ELIIDRLSKI LQNSQIPLLL
1160 1170 1180 1190 1200
QLTTGKSFQH LDSQFLGNPM DQFDKMQCFK KFYPDYNFDN VLHRLKSSKQ
1210 1220 1230 1240 1250
EQKRLRKTKL ATKERRQNIG LTKFSIFQAN SNVFKLIPQD FDINLYKPTY
1260 1270
LSYGTRMKKG NIYPINNFYL QNN
Length:1,273
Mass (Da):148,130
Last modified:April 16, 2014 - v2
Checksum:i52AD3A785B70D553
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG662561 Genomic DNA Translation: EAR82176.2
RefSeqiXP_001029839.2, XM_001029839.2

Genome annotation databases

EnsemblProtistsiEAR82176; EAR82176; TTHERM_01277520
GeneIDi7843331
KEGGitet:TTHERM_01277520

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG662561 Genomic DNA Translation: EAR82176.2
RefSeqiXP_001029839.2, XM_001029839.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5911.EAR82176

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAR82176; EAR82176; TTHERM_01277520
GeneIDi7843331
KEGGitet:TTHERM_01277520

Phylogenomic databases

InParanoidiQ22A56

Family and domain databases

CDDicd00038 CAP_ED, 1 hit
Gene3Di2.60.120.10, 1 hit
InterProiView protein in InterPro
IPR018490 cNMP-bd-like
IPR000595 cNMP-bd_dom
IPR005821 Ion_trans_dom
IPR014710 RmlC-like_jellyroll
IPR001878 Znf_CCHC
PfamiView protein in Pfam
PF00027 cNMP_binding, 1 hit
PF00520 Ion_trans, 1 hit
SMARTiView protein in SMART
SM00100 cNMP, 1 hit
SUPFAMiSSF51206 SSF51206, 1 hit
PROSITEiView protein in PROSITE
PS50042 CNMP_BINDING_3, 1 hit
PS50158 ZF_CCHC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ22A56_TETTS
AccessioniPrimary (citable) accession number: Q22A56
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 16, 2014
Last modified: November 7, 2018
This is version 70 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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