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Protein
Submitted name:

ASpartyl Protease

Gene

asp-13

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei90PROSITE-ProRule annotation1
Active sitei278PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotationSAAS annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.A83

Names & Taxonomyi

Protein namesi
Submitted name:
ASpartyl ProteaseImported
Gene namesi
Name:asp-13Imported
ORF Names:CELE_F28A12.4Imported, F28A12.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF28A12.4 ; CE09738 ; WBGene00017881 ; asp-13

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500420082617 – 389Sequence analysisAdd BLAST373

Proteomic databases

EPDiQ22972
PaxDbiQ22972
PeptideAtlasiQ22972

Expressioni

Gene expression databases

BgeeiWBGene00017881

Interactioni

Protein-protein interaction databases

STRINGi6239.F28A12.4.1

Structurei

3D structure databases

ProteinModelPortaliQ22972
SMRiQ22972
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini72 – 385Peptidase A1InterPro annotationAdd BLAST314

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
GeneTreeiENSGT00910000146616
HOGENOMiHOG000197681
InParanoidiQ22972
OMAiVDNITPP
OrthoDBiEOG091G098G
PhylomeDBiQ22972

Family and domain databases

CDDicd05471 pepsin_like, 1 hit
Gene3Di2.40.70.10, 3 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR034164 Pepsin-like_dom
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 1 hit
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Complete.

Q22972-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIISIIFLL IGSSTAAVLE HQLIWKESRM IEMIRNGEYP AYLEYRDRMV
60 70 80 90 100
ASRSSNLATV VQSTTDYVYY EYMGNITVGT PDQNFIVVLD TGSANLLIPG
110 120 130 140 150
TNCTTYCEKK RLFNEKASST YIATNRPWQI KYASGDAYGT LGIDTVKIGG
160 170 180 190 200
SGEAQLAIPR SYLGVADTVG SDFKWSPKEG IFGLAFTALA VDNITPPIIN
210 220 230 240 250
AINQGLLDQP LFTTWFGQRG APGTSASGAF TYGGLDKNHC GPVIGYAELT
260 270 280 290 300
NARHFQFQAT GFSLGSYVST TTYEVITDTA TSFLCGPQAA IDNLAKAAGA
310 320 330 340 350
TWDPTNQVFN IPCDADAGPI KMKIGQFNYV IRANNYILKI DTNSCLFAAI
360 370 380
PQNYAGFGPS WILGGPFMRQ YCNVHDIGQK RVGFCLSLA
Length:389
Mass (Da):42,238
Last modified:November 1, 1996 - v1
Checksum:iA76270702C900C98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD70115.1
PIRiT28954
RefSeqiNP_505232.1, NM_072831.4
UniGeneiCel.3850

Genome annotation databases

EnsemblMetazoaiF28A12.4.1; F28A12.4.1; WBGene00017881
F28A12.4.2; F28A12.4.2; WBGene00017881
GeneIDi179247
KEGGicel:CELE_F28A12.4
UCSCiF28A12.4.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ22972_CAEEL
AccessioniPrimary (citable) accession number: Q22972
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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