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Protein

Homeobox protein ceh-21

Gene

ceh-21

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable DNA-binding regulatory protein involved in cell-fate specification.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi284 – 370CUTPROSITE-ProRule annotationAdd BLAST87
DNA bindingi389 – 449HomeoboxPROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein ceh-21
Gene namesi
Name:ceh-21
ORF Names:T26C11.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiT26C11.6 ; CE29823 ; WBGene00000444 ; ceh-21

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002024081 – 495Homeobox protein ceh-21Add BLAST495

Proteomic databases

EPDiQ22811
PaxDbiQ22811
PRIDEiQ22811

Expressioni

Gene expression databases

BgeeiWBGene00000444

Interactioni

Protein-protein interaction databases

IntActiQ22811, 2 interactors
STRINGi6239.T26C11.6

Structurei

3D structure databases

ProteinModelPortaliQ22811
SMRiQ22811
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CUT homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

GeneTreeiENSGT00530000063019
InParanoidiQ22811
OrthoDBiEOG091G0E7H

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR003350 CUT_dom
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 1 hit
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 1 hit
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS51042 CUT, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q22811-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQQFQASSG TGSASLREFK TEHEDLREDL PYSTLRTLFG ITLDKDASQA
60 70 80 90 100
LNIALLLYGH NYPQQVVPPE RNYAELDAQL ESVVLEDHTA ESTMEPGVSA
110 120 130 140 150
TVTEQLEEKS DKSSDGDGTS KRLTRSLKSV ENETEEDHEE KEDEAPQSSR
160 170 180 190 200
RESTRLKRKL LESQKTVQTT GNSSRASSKS QEKEVPGTKS QCAPKIRTTP
210 220 230 240 250
EQSKAATKRQ SSTTVRASST CGSSVSSTST VSSPDYTAKK GRATETPKLE
260 270 280 290 300
ELAPKKQSSA TPKPGGEVCV WDGVQIGDLS AQMNAQIGDD EELDTVDIAR
310 320 330 340 350
RILSELKERC IPQTALAEKI LARSQGTLSD LLRMPKPWSV MKNGRATFQR
360 370 380 390 400
MSNWLGLDPD VRRALCFLPK EDVARITGLD EPTPAKRKKT VKVIRLTFTE
410 420 430 440 450
TQLKSLQKSF QQNHRPTREM RQKLSATLEL DFSTVGNFFM NSRRRLRIDQ
460 470 480 490
QISRSSRSTG NGADTEDELD EEDVVVENVI ADATDASNQP GPSHL
Length:495
Mass (Da):54,823
Last modified:June 6, 2002 - v3
Checksum:iC4FFA0984D0DAA08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ427855 mRNA Translation: CAD20808.1
FO080541 Genomic DNA Translation: CCD64528.1
AF023470 mRNA Translation: AAB86814.1
PIRiT28912
T42240
RefSeqiNP_508341.2, NM_075940.5
UniGeneiCel.9167

Genome annotation databases

EnsemblMetazoaiT26C11.6; T26C11.6; WBGene00000444
GeneIDi180504
KEGGicel:CELE_T26C11.6
UCSCiT26C11.6.2 c. elegans

Entry informationi

Entry nameiHM21_CAEEL
AccessioniPrimary (citable) accession number: Q22811
Secondary accession number(s): Q8WQE1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: June 6, 2002
Last modified: January 31, 2018
This is version 131 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

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