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Entry version 152 (18 Sep 2019)
Sequence version 2 (15 Jul 1999)
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Protein

Chromodomain-helicase-DNA-binding protein 3 homolog

Gene

chd-3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Chromatin-remodeling protein that has a role in notch signaling-dependent vulval cell fate determination. May also have a role in pharyngeal precursor cell specification.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri265 – 312PHD-type 1PROSITE-ProRule annotationAdd BLAST48
Zinc fingeri328 – 375PHD-type 2PROSITE-ProRule annotationAdd BLAST48
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi641 – 648ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • chromatin binding Source: WormBase
  • DNA binding Source: UniProtKB-KW
  • DNA helicase activity Source: WormBase
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, DNA-binding, Helicase, Hydrolase
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-3214815 HDACs deacetylate histones
R-CEL-8943724 Regulation of PTEN gene transcription

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chromodomain-helicase-DNA-binding protein 3 homolog (EC:3.6.4.12)
Short name:
CHD-3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:chd-3
ORF Names:T14G8.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
T14G8.1 ; CE03657 ; WBGene00000482 ; chd-3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000802341 – 1787Chromodomain-helicase-DNA-binding protein 3 homologAdd BLAST1787

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q22516

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q22516

PeptideAtlas

More...
PeptideAtlasi
Q22516

PRoteomics IDEntifications database

More...
PRIDEi
Q22516

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q22516

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the head and vulva.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Detected around the 20 cell stage after the onset of zygotic transcription. Also expressed in adults.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00000482 Expressed in 5 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.T14G8.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q22516

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini373 – 476Chromo 1PROSITE-ProRule annotationAdd BLAST104
Domaini501 – 583Chromo 2PROSITE-ProRule annotationAdd BLAST83
Domaini628 – 812Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST185
Domaini944 – 1107Helicase C-terminalPROSITE-ProRule annotationAdd BLAST164

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi763 – 766DEAH box4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi59 – 62Poly-Lys4
Compositional biasi1287 – 1291Poly-Arg5

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri265 – 312PHD-type 1PROSITE-ProRule annotationAdd BLAST48
Zinc fingeri328 – 375PHD-type 2PROSITE-ProRule annotationAdd BLAST48

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0383 Eukaryota
COG0553 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000169383

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231124

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q22516

KEGG Orthology (KO)

More...
KOi
K11643

Identification of Orthologs from Complete Genome Data

More...
OMAi
ITWRWAV

Database of Orthologous Groups

More...
OrthoDBi
54215at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q22516

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 2 hits
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012957 CHD_C2
IPR012958 CHD_N
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR009462 DUF1086
IPR009463 DUF1087
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08074 CHDCT2, 1 hit
PF08073 CHDNT, 1 hit
PF00385 Chromo, 1 hit
PF06461 DUF1086, 1 hit
PF06465 DUF1087, 1 hit
PF00271 Helicase_C, 1 hit
PF00628 PHD, 2 hits
PF00176 SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00298 CHROMO, 2 hits
SM00487 DEXDc, 1 hit
SM01146 DUF1086, 1 hit
SM01147 DUF1087, 1 hit
SM00490 HELICc, 1 hit
SM00249 PHD, 2 hits
SM00184 RING, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF54160 SSF54160, 2 hits
SSF57903 SSF57903, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50013 CHROMO_2, 1 hit
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS01359 ZF_PHD_1, 2 hits
PS50016 ZF_PHD_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q22516-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDDQHESID GDETMEEDSM LAEGHEDGEE DVGEDEEEVE TEESQGVPTT
60 70 80 90 100
SEKKKPPPKK KKGGKKSSKK KNNCDYPDPY KSTSAEISAA IGLTDVDVDY
110 120 130 140 150
EQEEFQSITN LKNFSSLVKP YILKVNPGTN VTKMYPLFQV KYKEFQDHMT
160 170 180 190 200
AHGKSIQKQQ RAKFVPVPVP VTPQEKIIPQ KTRSSARRKR RDGSDGEGGG
210 220 230 240 250
HDSDQEFEAL IKQHEKQQDE AEKGKEEARI NRAAAKVDKR KAALESARAS
260 270 280 290 300
KRARKEQGVV EENHQENCEV CNQDGELMLC DTCTRAYHVA CIDENMEQPP
310 320 330 340 350
EGDWSCPHCE EHGPDVLIVE EEPAKANMDY CRICKETSNI LLCDTCPSSY
360 370 380 390 400
HAYCIDPPLT EIPEGEWSCP RCIIPEPAQR IEKILSWRWK EISYPEPLEC
410 420 430 440 450
KEGEEASKDD VFLKPPRKME PRREREFFVK WKYLAYWQCE WLSETLMDVY
460 470 480 490 500
FTALVRMYWR KVDSENPPIF EESTLSRHHS DHDPYKLRER FYQYGVKPEW
510 520 530 540 550
MQIHRIINHL SYAKSQQDYL VKWKELSYEH ATWERDDTDI ANYEDAIIKY
560 570 580 590 600
WHHRERMLND EVPRNVQKMI AKQREAKGLG PKEDEVTSRR KKREKIDILK
610 620 630 640 650
KYEVQPDFIS ETGGNLHPYQ LEGINWLRHC WSNGTDAILA DEMGLGKTVQ
660 670 680 690 700
SLTFLYTLMK EGHTKGPFLI AAPLSTIINW EREAELWCPD FYVVTYVGDR
710 720 730 740 750
ESRMVIREHE FSFVDGAVRG GPKVSKIKTL ENLKFHVLLT SYECINMDKA
760 770 780 790 800
ILSSIDWAAL VVDEAHRLKN NQSTFFKNLR EYNIQYRVLL TGTPLQNNLE
810 820 830 840 850
ELFHLLNFLA PDRFNQLESF TAEFSEISKE DQIEKLHNLL GPHMLRRLKA
860 870 880 890 900
DVLTGMPSKQ ELIVRVELSA MQKKYYKNIL TRNFDALNVK NGGTQMSLIN
910 920 930 940 950
IIMELKKCCN HPYLFMKACL EAPKLKNGMY EGSALIKNAG KFVLLQKMLR
960 970 980 990 1000
KLKDGGHRVL IFSQMTMMLD ILEDFCDVEG YKYERIDGSI TGQQRQDAID
1010 1020 1030 1040 1050
RYNAPGAKQF VFLLSTRAGG LGINLATADT VIIYDSDWNP HNDIQAFSRA
1060 1070 1080 1090 1100
HRLGQKHKVM IYRFVTKGSV EERITSVAKK KMLLTHLVVR AGLGAKDGKS
1110 1120 1130 1140 1150
MSKTELDDVL RWGTEELFKE EEAPVEGADG EGTSSKKPNE QEIVWDDAAV
1160 1170 1180 1190 1200
DFLLDRNKEE EGQDGEKKEH WTNEYLSSFK VATYNTKEAD DADDDEDETE
1210 1220 1230 1240 1250
VIKEGTEEQD PNYWEKLLKH HYEQDQETEL QKLGKGKRVR RQVNYASENM
1260 1270 1280 1290 1300
GQDWSAQNNQ QQEEDDGSEY GSDNGELLQT DEDYEERRRR REERSEKLPP
1310 1320 1330 1340 1350
LLAKVNGQIE VLGFNPRQRK AFYNAVMRWG MPPQDLTQSS WQVRDLRNKS
1360 1370 1380 1390 1400
EKVFKAYSSL FMRHLCEPVV DNSDSFMDGV PREGLNRQAV LSRIGLMSIL
1410 1420 1430 1440 1450
RKKVQEFEKF NGEWSMPETR EKMLATAAQA SVSNLPGMIK IKEEPIDIDE
1460 1470 1480 1490 1500
TPMDVDQSNI TKTEELASEV KVEEEPKAPR LPYKFNICDG GYTELHSLWI
1510 1520 1530 1540 1550
NEEKVARNGK EYEIWHRRHD FWLLAAVAVY GYGRYQINFQ DIMNDPKFSI
1560 1570 1580 1590 1600
VNEPFKQTGA DPATNFADVK NKFLARRFKL LEQSLVIEEQ LRRAAHINKQ
1610 1620 1630 1640 1650
QSPDQVGQLA QHFSELEHTA DAHVNIARES NNGNRNANAI LHKCLAQLDD
1660 1670 1680 1690 1700
LLSDLKTDVA RLPATISQVR PVTERLQMSE RQILSRLVVA KDPDAAPSKP
1710 1720 1730 1740 1750
ALPPSGPFIT PLFNQNFTTI QPKFPSLFDC NLSPDDEPID IEGSISAAVA
1760 1770 1780
EASRASSIAA TKDEPMDTSD KDIPSTSAAA GSSYPRY
Length:1,787
Mass (Da):205,255
Last modified:July 15, 1999 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1EFCE1FFECE59740
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF308444 mRNA Translation: AAG29837.1
Z67884, Z67881 Genomic DNA Translation: CAA91810.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T20160

NCBI Reference Sequences

More...
RefSeqi
NP_510140.1, NM_077739.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
T14G8.1.1; T14G8.1.1; WBGene00000482

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181421

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_T14G8.1

UCSC genome browser

More...
UCSCi
T14G8.1 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF308444 mRNA Translation: AAG29837.1
Z67884, Z67881 Genomic DNA Translation: CAA91810.1
PIRiT20160
RefSeqiNP_510140.1, NM_077739.4

3D structure databases

SMRiQ22516
ModBaseiSearch...

Protein-protein interaction databases

STRINGi6239.T14G8.1

PTM databases

iPTMnetiQ22516

Proteomic databases

EPDiQ22516
PaxDbiQ22516
PeptideAtlasiQ22516
PRIDEiQ22516

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT14G8.1.1; T14G8.1.1; WBGene00000482
GeneIDi181421
KEGGicel:CELE_T14G8.1
UCSCiT14G8.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181421
WormBaseiT14G8.1 ; CE03657 ; WBGene00000482 ; chd-3

Phylogenomic databases

eggNOGiKOG0383 Eukaryota
COG0553 LUCA
GeneTreeiENSGT00940000169383
HOGENOMiHOG000231124
InParanoidiQ22516
KOiK11643
OMAiITWRWAV
OrthoDBi54215at2759
PhylomeDBiQ22516

Enzyme and pathway databases

ReactomeiR-CEL-3214815 HDACs deacetylate histones
R-CEL-8943724 Regulation of PTEN gene transcription

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q22516

Gene expression databases

BgeeiWBGene00000482 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

Gene3Di3.30.40.10, 2 hits
3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR012957 CHD_C2
IPR012958 CHD_N
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR002464 DNA/RNA_helicase_DEAH_CS
IPR009462 DUF1086
IPR009463 DUF1087
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF08074 CHDCT2, 1 hit
PF08073 CHDNT, 1 hit
PF00385 Chromo, 1 hit
PF06461 DUF1086, 1 hit
PF06465 DUF1087, 1 hit
PF00271 Helicase_C, 1 hit
PF00628 PHD, 2 hits
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 2 hits
SM00487 DEXDc, 1 hit
SM01146 DUF1086, 1 hit
SM01147 DUF1087, 1 hit
SM00490 HELICc, 1 hit
SM00249 PHD, 2 hits
SM00184 RING, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF54160 SSF54160, 2 hits
SSF57903 SSF57903, 2 hits
PROSITEiView protein in PROSITE
PS50013 CHROMO_2, 1 hit
PS00690 DEAH_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS01359 ZF_PHD_1, 2 hits
PS50016 ZF_PHD_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCHD3_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q22516
Secondary accession number(s): Q18794
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: July 15, 1999
Last modified: September 18, 2019
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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