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Protein
Submitted name:

Proteasome Regulatory Particle, Non-ATPase-like

Gene

rpn-9

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CEL-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
R-CEL-1236978 Cross-presentation of soluble exogenous antigens (endosomes)
R-CEL-174113 SCF-beta-TrCP mediated degradation of Emi1
R-CEL-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA
R-CEL-4608870 Asymmetric localization of PCP proteins
R-CEL-5632684 Hedgehog 'on' state
R-CEL-5668541 TNFR2 non-canonical NF-kB pathway
R-CEL-5689603 UCH proteinases
R-CEL-5689880 Ub-specific processing proteases
R-CEL-6798695 Neutrophil degranulation
R-CEL-68949 Orc1 removal from chromatin
R-CEL-69229 Ubiquitin-dependent degradation of Cyclin D1
R-CEL-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
R-CEL-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-CEL-8939902 Regulation of RUNX2 expression and activity
R-CEL-8941858 Regulation of RUNX3 expression and activity
R-CEL-8948751 Regulation of PTEN stability and activity
R-CEL-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Submitted name:
Proteasome Regulatory Particle, Non-ATPase-likeImported
Gene namesi
Name:rpn-9Imported
ORF Names:CELE_T06D8.8Imported, T06D8.8Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiT06D8.8 ; CE02329 ; WBGene00004465 ; rpn-9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiQ22253
PaxDbiQ22253
PeptideAtlasiQ22253

Expressioni

Gene expression databases

BgeeiWBGene00004465

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
rpn-8O617924EBI-326317,EBI-324407

Protein-protein interaction databases

IntActiQ22253, 4 interactors
STRINGi6239.T06D8.8.1

Structurei

3D structure databases

ProteinModelPortaliQ22253
SMRiQ22253
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini177 – 347PCIInterPro annotationAdd BLAST171

Phylogenomic databases

eggNOGiKOG2908 Eukaryota
ENOG410XPG9 LUCA
GeneTreeiENSGT00390000001802
HOGENOMiHOG000216633
InParanoidiQ22253
KOiK03039
OMAiKFADKIN
OrthoDBiEOG091G0977
PhylomeDBiQ22253

Family and domain databases

InterProiView protein in InterPro
IPR000717 PCI_dom
IPR035298 PSMD13
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR10539 PTHR10539, 1 hit
PfamiView protein in Pfam
PF01399 PCI, 1 hit
SMARTiView protein in SMART
SM00088 PINT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit

Sequencei

Sequence statusi: Complete.

Q22253-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAQDYLNGK LAAANGPLAD DWKNLKELWE KKLWHQLTVL TRSLVKKPQF
60 70 80 90 100
VASTDMHEFY RLFVAEWELR VNPLQLVEIC ISIAQNIATK DKQKSMEFLS
110 120 130 140 150
KIGNVINKDK IAVARLHTGE IEARLENKDK NGQIIDLKSI RTQIDSTQHE
160 170 180 190 200
VDSLVGVTEV HAPFYRVSSL YLREVGDFAG YYREALRYLG VEDANNLTTE
210 220 230 240 250
QKQVHAVLLG FAALLGENVH NFGELLAHPI LKSLEGTRER WIVDVLLAFN
260 270 280 290 300
SGDLTRFFSL EGDWGGWDDL KKQKDFLTAK IRLMAVMELA VSRPTKARSV
310 320 330 340 350
SFKEIATKCQ IPFDEVEFLV MKALSKDLIR GDINQVEQVV YVTWVQPRVL
360 370 380
DNPQIMQMAT RISAWRNDVN SMEGIVSKEA REILTQN
Length:387
Mass (Da):44,160
Last modified:November 1, 1996 - v1
Checksum:i3E4D1D15B2616A6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAA88971.1
PIRiT24581
RefSeqiNP_496405.1, NM_064004.5
UniGeneiCel.5073

Genome annotation databases

EnsemblMetazoaiT06D8.8.1; T06D8.8.1; WBGene00004465
T06D8.8.2; T06D8.8.2; WBGene00004465
GeneIDi174715
KEGGicel:CELE_T06D8.8
UCSCiT06D8.8.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ22253_CAEEL
AccessioniPrimary (citable) accession number: Q22253
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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