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Entry version 132 (08 May 2019)
Sequence version 3 (01 May 1999)
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Protein

Transcription elongation factor SPT5

Gene

spt-5

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-112382 Formation of RNA Pol II elongation complex
R-CEL-113418 Formation of the Early Elongation Complex
R-CEL-674695 RNA Polymerase II Pre-transcription Events
R-CEL-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-CEL-72086 mRNA Capping
R-CEL-75955 RNA Polymerase II Transcription Elongation
R-CEL-77075 RNA Pol II CTD phosphorylation and interaction with CE

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription elongation factor SPT5
Alternative name(s):
DRB sensitivity-inducing factor large subunit
Short name:
DSIF large subunit
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:spt-5
ORF Names:K08E4.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
K08E4.1 ; CE06145 ; WBGene00005015 ; spt-5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002084741 – 1208Transcription elongation factor SPT5Add BLAST1208

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei815Phosphothreonine; by CDK9By similarity1
Modified residuei822Phosphothreonine; by CDK9By similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated. Phosphorylation by P-TEFb alleviates transcriptional pausing (By similarity).By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q21338

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q21338

PeptideAtlas

More...
PeptideAtlasi
Q21338

PRoteomics IDEntifications database

More...
PRIDEi
Q21338

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q21338

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00005015 Expressed in 5 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with spt-4 to form DSIF. DSIF interacts with RNA polymerase II and with the positive transcription elongation factor b complex (P-TEFb complex), which is composed of cdk-9 and cyclin-T (cit-1.1 or cit-1.2) (By similarity).By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.K08E4.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q21338

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini420 – 447KOW 1Add BLAST28
Domaini473 – 506KOW 2Add BLAST34
Domaini595 – 629KOW 3Add BLAST35
Domaini730 – 763KOW 4Add BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni182 – 274Interaction with SPT4By similarityAdd BLAST93
Regioni317 – 421Interaction with RNA polymerase IIBy similarityAdd BLAST105

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi4 – 105Asp-richAdd BLAST102
Compositional biasi708 – 715Poly-Gly8

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPT5 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1999 Eukaryota
COG0250 LUCA
COG5164 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000037640

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000038564

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q21338

KEGG Orthology (KO)

More...
KOi
K15172

Identification of Orthologs from Complete Genome Data

More...
OMAi
FLAWDVE

Database of Orthologous Groups

More...
OrthoDBi
828863at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q21338

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06081 KOW_Spt5_1, 1 hit
cd06082 KOW_Spt5_2, 1 hit
cd06083 KOW_Spt5_3, 1 hit
cd06084 KOW_Spt5_4, 1 hit
cd06085 KOW_Spt5_5, 1 hit
cd06086 KOW_Spt5_6, 1 hit
cd09888 NGN_Euk, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.30, 3 hits
3.30.70.940, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005824 KOW
IPR041973 KOW_Spt5_1
IPR041975 KOW_Spt5_2
IPR041976 KOW_Spt5_3
IPR041977 KOW_Spt5_4
IPR041978 KOW_Spt5_5
IPR041980 KOW_Spt5_6
IPR005100 NGN-domain
IPR006645 NGN_dom
IPR036735 NGN_dom_sf
IPR039385 NGN_Euk
IPR014722 Rib_L2_dom2
IPR039659 SPT5
IPR024945 Spt5_C_dom
IPR022581 Spt5_N
IPR017071 TF_Spt5_eukaryote
IPR008991 Translation_prot_SH3-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11125 PTHR11125, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00467 KOW, 1 hit
PF03439 Spt5-NGN, 1 hit
PF11942 Spt5_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036945 Spt5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01104 CTD, 2 hits
SM00739 KOW, 5 hits
SM00738 NGN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50104 SSF50104, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q21338-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSDESDAAS NKEEDTTLSD DDGSDVEIKN SKKDRKRKLA SESEKSGSDD
60 70 80 90 100
DDDDDDDEDE NVTSKKSKKQ KRKNKAPSGR DFLAWDVEVD DEDEDDDNDY
110 120 130 140 150
DDEDDPSMNA MNEREEAERA MKEMELSQRN RDRYKFQNMT EDEVQKYFEN
160 170 180 190 200
KYKGDKNDSQ YDDEDSAMDD ISKNSHLPST KDPNLWIVKC RMGEEKLVAM
210 220 230 240 250
HLMRKCLAVE HTNEPFQIKS VVVKEGLKGM IYIEAFKQSH VMSAIEGFSA
260 270 280 290 300
LNQFTITMVP IKDMVDVLRV VKDIPQLKLG SYVRLKRTMY KDDLAVVDLV
310 320 330 340 350
DIAQNRVNLK LIPRVDYQKR RGAMRTDADK NYKLKRRPMP KLFDQDTIKE
360 370 380 390 400
VGGEIVTDGD FLVFEGNHFR RGFLYKYFPI NAIQADGVKP TLGELEKFQE
410 420 430 440 450
SSDDLKRELE TASLKDTENP FVPGDIVEVK AGELVNLRGK VMTVDGTKVV
460 470 480 490 500
MMPDQEDLKE AITLNAHELR KYFKEGDHAK VISGRYEGHT GLIVRVKDST
510 520 530 540 550
AIVLSDLGME ELKVRVRDLQ LCADVTTGVD SLGQFQYHDL VQLDHTGNVG
560 570 580 590 600
VIVRLEKEHL EVLNMHGVVN RIKPQAIIAK KDVRFAKVLD SQNNSIEAKD
610 620 630 640 650
LVKVIGGPNA KERETDEDPV GEVLYAFRGT VFVYSRKVTK NGGVLVCKPK
660 670 680 690 700
QLILQGAKKT TSTPMVSRMA SPNPMASPRH SSGGMTPRSP QDGMSSRGSS
710 720 730 740 750
GGQTPRQGGG GGRGGHFGTA NQQKVRRDLT LIGKNVRIIK GPMKGHFGIV
760 770 780 790 800
RDATEDTVRV ELHTQCRTIS VDRARVMVVG DTGITAGSGG GSSFYSSSKT
810 820 830 840 850
PMRDSGKTPM YGSKTPMYGA QTPMYGSMTP AYDGGRTPAY GEGGRTPAYG
860 870 880 890 900
SKTPAYGDLD EHSSSRTPAY GNDSSRTPAY GSADGARTPA YGSTEGGRTP
910 920 930 940 950
AYGSMDNSRT PAYDDSGRTP GYESMPSRTP NYDSSSKTPA YPESEHSART
960 970 980 990 1000
PAYNNDYDIP LSPAYEPDAP EAYDNAPART PAFVSRTPGY DTYENSSPTY
1010 1020 1030 1040 1050
EPDAATKVEE DIGDTSSPTY DSPPHSYVVP TPGAMLNPAT PGAYHVDTPG
1060 1070 1080 1090 1100
FAAPMTPGSG GAYDQYVAPS PFAGYDSNNY NNADGAIEQI PDHFLAQGVW
1110 1120 1130 1140 1150
IVQNLCVQIK DHEGRFNGRE AIIKDVTDGK VDVYMPDHKC NLEVDFDQLT
1160 1170 1180 1190 1200
PMKPQPGDDA RVIFGQDAGH SGQLVSMDGF EAVIRSQEDM SDMRVINIGL

CCKMHSET
Length:1,208
Mass (Da):133,357
Last modified:May 1, 1999 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i30BA1B988A305660
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z68316, Z68752 Genomic DNA Translation: CAA92685.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T23467

NCBI Reference Sequences

More...
RefSeqi
NP_502283.1, NM_069882.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
K08E4.1.1; K08E4.1.1; WBGene00005015
K08E4.1.2; K08E4.1.2; WBGene00005015

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
178143

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_K08E4.1

UCSC genome browser

More...
UCSCi
K08E4.1 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68316, Z68752 Genomic DNA Translation: CAA92685.1
PIRiT23467
RefSeqiNP_502283.1, NM_069882.5

3D structure databases

SMRiQ21338
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.K08E4.1

PTM databases

iPTMnetiQ21338

Proteomic databases

EPDiQ21338
PaxDbiQ21338
PeptideAtlasiQ21338
PRIDEiQ21338

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK08E4.1.1; K08E4.1.1; WBGene00005015
K08E4.1.2; K08E4.1.2; WBGene00005015
GeneIDi178143
KEGGicel:CELE_K08E4.1
UCSCiK08E4.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
178143
WormBaseiK08E4.1 ; CE06145 ; WBGene00005015 ; spt-5

Phylogenomic databases

eggNOGiKOG1999 Eukaryota
COG0250 LUCA
COG5164 LUCA
GeneTreeiENSGT00440000037640
HOGENOMiHOG000038564
InParanoidiQ21338
KOiK15172
OMAiFLAWDVE
OrthoDBi828863at2759
PhylomeDBiQ21338

Enzyme and pathway databases

ReactomeiR-CEL-112382 Formation of RNA Pol II elongation complex
R-CEL-113418 Formation of the Early Elongation Complex
R-CEL-674695 RNA Polymerase II Pre-transcription Events
R-CEL-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-CEL-72086 mRNA Capping
R-CEL-75955 RNA Polymerase II Transcription Elongation
R-CEL-77075 RNA Pol II CTD phosphorylation and interaction with CE

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q21338

Gene expression databases

BgeeiWBGene00005015 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd06081 KOW_Spt5_1, 1 hit
cd06082 KOW_Spt5_2, 1 hit
cd06083 KOW_Spt5_3, 1 hit
cd06084 KOW_Spt5_4, 1 hit
cd06085 KOW_Spt5_5, 1 hit
cd06086 KOW_Spt5_6, 1 hit
cd09888 NGN_Euk, 1 hit
Gene3Di2.30.30.30, 3 hits
3.30.70.940, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR041973 KOW_Spt5_1
IPR041975 KOW_Spt5_2
IPR041976 KOW_Spt5_3
IPR041977 KOW_Spt5_4
IPR041978 KOW_Spt5_5
IPR041980 KOW_Spt5_6
IPR005100 NGN-domain
IPR006645 NGN_dom
IPR036735 NGN_dom_sf
IPR039385 NGN_Euk
IPR014722 Rib_L2_dom2
IPR039659 SPT5
IPR024945 Spt5_C_dom
IPR022581 Spt5_N
IPR017071 TF_Spt5_eukaryote
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR11125 PTHR11125, 3 hits
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF03439 Spt5-NGN, 1 hit
PF11942 Spt5_N, 1 hit
PIRSFiPIRSF036945 Spt5, 1 hit
SMARTiView protein in SMART
SM01104 CTD, 2 hits
SM00739 KOW, 5 hits
SM00738 NGN, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPT5H_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q21338
Secondary accession number(s): Q22440
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: May 1, 1999
Last modified: May 8, 2019
This is version 132 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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