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UniProtKB - Q21338 (SPT5H_CAEEL)

Entry version 142 (25 May 2022)
Sequence version 3 (01 May 1999)
Previous versions | rss
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Protein

Transcription elongation factor SPT5

Gene

spt-5

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: GO_Central
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-CEL-112382, Formation of RNA Pol II elongation complex
R-CEL-113418, Formation of the Early Elongation Complex
R-CEL-674695, RNA Polymerase II Pre-transcription Events
R-CEL-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-CEL-72086, mRNA Capping
R-CEL-75955, RNA Polymerase II Transcription Elongation
R-CEL-77075, RNA Pol II CTD phosphorylation and interaction with CE

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription elongation factor SPT5
Alternative name(s):
DRB sensitivity-inducing factor large subunit
Short name:
DSIF large subunit
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:spt-5
ORF Names:K08E4.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...WormBasei		K08E4.1 ; CE06145 ; WBGene00005015 ; spt-5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002084741 – 1208Transcription elongation factor SPT5Add BLAST1208

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei815Phosphothreonine; by CDK9By similarity1
Modified residuei822Phosphothreonine; by CDK9By similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated. Phosphorylation by P-TEFb alleviates transcriptional pausing (By similarity).By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q21338

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q21338

PeptideAtlas

More...PeptideAtlasi		Q21338

PRoteomics IDEntifications database

More...PRIDEi		Q21338

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q21338

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		WBGene00005015, Expressed in multi-cellular organism and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with spt-4 to form DSIF. DSIF interacts with RNA polymerase II and with the positive transcription elongation factor b complex (P-TEFb complex), which is composed of cdk-9 and cyclin-T (cit-1.1 or cit-1.2) (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		43237, 9 interactors

STRING: functional protein association networks

More...STRINGi		6239.K08E4.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q21338

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q21338

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini420 – 447KOW 1Add BLAST28
Domaini473 – 506KOW 2Add BLAST34
Domaini595 – 629KOW 3Add BLAST35
Domaini730 – 763KOW 4Add BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 116DisorderedSequence analysisAdd BLAST116
Regioni151 – 176DisorderedSequence analysisAdd BLAST26
Regioni182 – 274Interaction with SPT4By similarityAdd BLAST93
Regioni317 – 421Interaction with RNA polymerase IIBy similarityAdd BLAST105
Regioni658 – 726DisorderedSequence analysisAdd BLAST69
Regioni792 – 812DisorderedSequence analysisAdd BLAST21
Regioni836 – 1004DisorderedSequence analysisAdd BLAST169

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi7 – 45Basic and acidic residuesSequence analysisAdd BLAST39
Compositional biasi46 – 60Acidic residuesSequence analysisAdd BLAST15
Compositional biasi86 – 109Acidic residuesSequence analysisAdd BLAST24
Compositional biasi151 – 171Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi658 – 706Polar residuesSequence analysisAdd BLAST49
Compositional biasi865 – 881Polar residuesSequence analysisAdd BLAST17
Compositional biasi900 – 914Polar residuesSequence analysisAdd BLAST15
Compositional biasi922 – 951Polar residuesSequence analysisAdd BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPT5 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1999, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00440000037640

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_003537_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q21338

Identification of Orthologs from Complete Genome Data

More...OMAi		FLAWDVE

Database of Orthologous Groups

More...OrthoDBi		828863at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q21338

Family and domain databases

Conserved Domains Database

More...CDDi		cd06081, KOW_Spt5_1, 1 hit
cd06082, KOW_Spt5_2, 1 hit
cd06083, KOW_Spt5_3, 1 hit
cd06084, KOW_Spt5_4, 1 hit
cd06085, KOW_Spt5_5, 1 hit
cd06086, KOW_Spt5_6, 1 hit
cd09888, NGN_Euk, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.30.30, 3 hits
3.30.70.940, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005824, KOW
IPR041973, KOW_Spt5_1
IPR041975, KOW_Spt5_2
IPR041976, KOW_Spt5_3
IPR041977, KOW_Spt5_4
IPR041978, KOW_Spt5_5
IPR041980, KOW_Spt5_6
IPR005100, NGN-domain
IPR006645, NGN_dom
IPR036735, NGN_dom_sf
IPR039385, NGN_Euk
IPR014722, Rib_L2_dom2
IPR039659, SPT5
IPR024945, Spt5_C_dom
IPR022581, Spt5_N
IPR017071, TF_Spt5_eukaryote
IPR008991, Translation_prot_SH3-like_sf

The PANTHER Classification System

More...PANTHERi		PTHR11125, PTHR11125, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00467, KOW, 1 hit
PF03439, Spt5-NGN, 1 hit
PF11942, Spt5_N, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF036945, Spt5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01104, CTD, 2 hits
SM00739, KOW, 5 hits
SM00738, NGN, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50104, SSF50104, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q21338-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSDESDAAS NKEEDTTLSD DDGSDVEIKN SKKDRKRKLA SESEKSGSDD 
        60         70         80         90        100
DDDDDDDEDE NVTSKKSKKQ KRKNKAPSGR DFLAWDVEVD DEDEDDDNDY 
       110        120        130        140        150
DDEDDPSMNA MNEREEAERA MKEMELSQRN RDRYKFQNMT EDEVQKYFEN 
       160        170        180        190        200
KYKGDKNDSQ YDDEDSAMDD ISKNSHLPST KDPNLWIVKC RMGEEKLVAM 
       210        220        230        240        250
HLMRKCLAVE HTNEPFQIKS VVVKEGLKGM IYIEAFKQSH VMSAIEGFSA 
       260        270        280        290        300
LNQFTITMVP IKDMVDVLRV VKDIPQLKLG SYVRLKRTMY KDDLAVVDLV 
       310        320        330        340        350
DIAQNRVNLK LIPRVDYQKR RGAMRTDADK NYKLKRRPMP KLFDQDTIKE 
       360        370        380        390        400
VGGEIVTDGD FLVFEGNHFR RGFLYKYFPI NAIQADGVKP TLGELEKFQE 
       410        420        430        440        450
SSDDLKRELE TASLKDTENP FVPGDIVEVK AGELVNLRGK VMTVDGTKVV 
       460        470        480        490        500
MMPDQEDLKE AITLNAHELR KYFKEGDHAK VISGRYEGHT GLIVRVKDST 
       510        520        530        540        550
AIVLSDLGME ELKVRVRDLQ LCADVTTGVD SLGQFQYHDL VQLDHTGNVG 
       560        570        580        590        600
VIVRLEKEHL EVLNMHGVVN RIKPQAIIAK KDVRFAKVLD SQNNSIEAKD 
       610        620        630        640        650
LVKVIGGPNA KERETDEDPV GEVLYAFRGT VFVYSRKVTK NGGVLVCKPK 
       660        670        680        690        700
QLILQGAKKT TSTPMVSRMA SPNPMASPRH SSGGMTPRSP QDGMSSRGSS 
       710        720        730        740        750
GGQTPRQGGG GGRGGHFGTA NQQKVRRDLT LIGKNVRIIK GPMKGHFGIV 
       760        770        780        790        800
RDATEDTVRV ELHTQCRTIS VDRARVMVVG DTGITAGSGG GSSFYSSSKT 
       810        820        830        840        850
PMRDSGKTPM YGSKTPMYGA QTPMYGSMTP AYDGGRTPAY GEGGRTPAYG 
       860        870        880        890        900
SKTPAYGDLD EHSSSRTPAY GNDSSRTPAY GSADGARTPA YGSTEGGRTP 
       910        920        930        940        950
AYGSMDNSRT PAYDDSGRTP GYESMPSRTP NYDSSSKTPA YPESEHSART 
       960        970        980        990       1000
PAYNNDYDIP LSPAYEPDAP EAYDNAPART PAFVSRTPGY DTYENSSPTY 
      1010       1020       1030       1040       1050
EPDAATKVEE DIGDTSSPTY DSPPHSYVVP TPGAMLNPAT PGAYHVDTPG 
      1060       1070       1080       1090       1100
FAAPMTPGSG GAYDQYVAPS PFAGYDSNNY NNADGAIEQI PDHFLAQGVW 
      1110       1120       1130       1140       1150
IVQNLCVQIK DHEGRFNGRE AIIKDVTDGK VDVYMPDHKC NLEVDFDQLT 
      1160       1170       1180       1190       1200
PMKPQPGDDA RVIFGQDAGH SGQLVSMDGF EAVIRSQEDM SDMRVINIGL 

CCKMHSET
Length:1,208
Mass (Da):133,357
Last modified:May 1, 1999 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i30BA1B988A305660
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Z68316, Z68752 Genomic DNA Translation: CAA92685.1

Protein sequence database of the Protein Information Resource

More...PIRi		T23467

NCBI Reference Sequences

More...RefSeqi		NP_502283.1, NM_069882.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		K08E4.1.1; K08E4.1.1; WBGene00005015
K08E4.1.2; K08E4.1.2; WBGene00005015

Database of genes from NCBI RefSeq genomes

More...GeneIDi		178143

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		cel:CELE_K08E4.1

UCSC genome browser

More...UCSCi		K08E4.1, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68316, Z68752 Genomic DNA Translation: CAA92685.1
PIRiT23467
RefSeqiNP_502283.1, NM_069882.5

3D structure databases

AlphaFoldDBiQ21338
SMRiQ21338
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi43237, 9 interactors
STRINGi6239.K08E4.1

PTM databases

iPTMnetiQ21338

Proteomic databases

EPDiQ21338
PaxDbiQ21338
PeptideAtlasiQ21338
PRIDEiQ21338

Genome annotation databases

EnsemblMetazoaiK08E4.1.1; K08E4.1.1; WBGene00005015
K08E4.1.2; K08E4.1.2; WBGene00005015
GeneIDi178143
KEGGicel:CELE_K08E4.1
UCSCiK08E4.1, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		178143
WormBaseiK08E4.1 ; CE06145 ; WBGene00005015 ; spt-5

Phylogenomic databases

eggNOGiKOG1999, Eukaryota
GeneTreeiENSGT00440000037640
HOGENOMiCLU_003537_0_0_1
InParanoidiQ21338
OMAiFLAWDVE
OrthoDBi828863at2759
PhylomeDBiQ21338

Enzyme and pathway databases

ReactomeiR-CEL-112382, Formation of RNA Pol II elongation complex
R-CEL-113418, Formation of the Early Elongation Complex
R-CEL-674695, RNA Polymerase II Pre-transcription Events
R-CEL-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-CEL-72086, mRNA Capping
R-CEL-75955, RNA Polymerase II Transcription Elongation
R-CEL-77075, RNA Pol II CTD phosphorylation and interaction with CE

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q21338

Gene expression databases

BgeeiWBGene00005015, Expressed in multi-cellular organism and 5 other tissues

Family and domain databases

CDDicd06081, KOW_Spt5_1, 1 hit
cd06082, KOW_Spt5_2, 1 hit
cd06083, KOW_Spt5_3, 1 hit
cd06084, KOW_Spt5_4, 1 hit
cd06085, KOW_Spt5_5, 1 hit
cd06086, KOW_Spt5_6, 1 hit
cd09888, NGN_Euk, 1 hit
Gene3Di2.30.30.30, 3 hits
3.30.70.940, 1 hit
InterProiView protein in InterPro
IPR005824, KOW
IPR041973, KOW_Spt5_1
IPR041975, KOW_Spt5_2
IPR041976, KOW_Spt5_3
IPR041977, KOW_Spt5_4
IPR041978, KOW_Spt5_5
IPR041980, KOW_Spt5_6
IPR005100, NGN-domain
IPR006645, NGN_dom
IPR036735, NGN_dom_sf
IPR039385, NGN_Euk
IPR014722, Rib_L2_dom2
IPR039659, SPT5
IPR024945, Spt5_C_dom
IPR022581, Spt5_N
IPR017071, TF_Spt5_eukaryote
IPR008991, Translation_prot_SH3-like_sf
PANTHERiPTHR11125, PTHR11125, 1 hit
PfamiView protein in Pfam
PF00467, KOW, 1 hit
PF03439, Spt5-NGN, 1 hit
PF11942, Spt5_N, 1 hit
PIRSFiPIRSF036945, Spt5, 1 hit
SMARTiView protein in SMART
SM01104, CTD, 2 hits
SM00739, KOW, 5 hits
SM00738, NGN, 1 hit
SUPFAMiSSF50104, SSF50104, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPT5H_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q21338
Secondary accession number(s): Q22440
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: May 1, 1999
Last modified: May 25, 2022
This is version 142 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
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