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Entry version 144 (26 Feb 2020)
Sequence version 1 (01 Nov 1996)
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Protein

Multifunctional procollagen lysine hydroxylase and glycosyltransferase

Gene

let-268

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Multifunctional enzyme that catalyzes a series of post-translational modifications on Lys residues in procollagen (PubMed:11896059). Catalyzes the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in type IV collagens (By similarity). Transfers galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine (By similarity). Catalyzes the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:11896059). Essential for normal biosynthesis and secretion of type IV collagens (PubMed:11071784, PubMed:11896059). Essential for normal stability of the basement membrane (PubMed:11071784).By similarity2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi98ManganeseBy similarity1
Metal bindingi101ManganeseBy similarity1
Metal bindingi242ManganeseBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei5902-oxoglutarateBy similarity1
Binding sitei6482-oxoglutarateBy similarity1
Metal bindingi659IronPROSITE-ProRule annotation1
Metal bindingi661IronPROSITE-ProRule annotation1
Metal bindingi711IronPROSITE-ProRule annotation1
Binding sitei7212-oxoglutarateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase
LigandIron, Manganese, Metal-binding, Vitamin C

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-1650814 Collagen biosynthesis and modifying enzymes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Multifunctional procollagen lysine hydroxylase and glycosyltransferase
Alternative name(s):
Lethal protein 268
Including the following 2 domains:
Procollagen-lysine,2-oxoglutarate 5-dioxygenase (EC:1.14.11.4By similarity)
Alternative name(s):
Lysyl hydroxylase
Short name:
LH
Procollagen glycosyltransferase (EC:2.4.1.50By similarity, EC:2.4.1.661 Publication)
Alternative name(s):
Galactosylhydroxylysine-glucosyltransferase
Procollagen galactosyltransferase
Procollagen glucosyltransferase
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:let-268
ORF Names:F52H3.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
F52H3.1 ; CE03397 ; WBGene00002497 ; let-268

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi131F → I: Nearly abolishes glucosyltransferase activity. 1 Publication1
Mutagenesisi132C → I: Loss of glucosyltransferase activity. 1 Publication1
Mutagenesisi196L → I: Strongly reduced glucosyltransferase activity. 1 Publication1
Mutagenesisi453A → I: Loss of glucosyltransferase activity. 1 Publication1
Mutagenesisi668D → R in let-268(mn189); lethal effect. 1 Publication1
Mutagenesisi682G → D in let-268(mn198); lethal effect. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 16Sequence analysisAdd BLAST16
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002468917 – 730Multifunctional procollagen lysine hydroxylase and glycosyltransferaseAdd BLAST714

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi268 ↔ 271By similarity
Disulfide bondi554 ↔ 690By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi689N-linked (GlcNAc...) asparagine2 Publications1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q20679

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q20679

PeptideAtlas

More...
PeptideAtlasi
Q20679

PRoteomics IDEntifications database

More...
PRIDEi
Q20679

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q20679

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00002497 Expressed in multi-cellular organism and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
39884, 1 interactor

STRING: functional protein association networks

More...
STRINGi
6239.F52H3.1.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q20679

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini639 – 730Fe2OG dioxygenasePROSITE-ProRule annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni20 – 280Required for glycosyltransferase activityBy similarityAdd BLAST261
Regioni30 – 32UDP-sugar bindingBy similarity3
Regioni98 – 100UDP-sugar bindingBy similarity3
Regioni245 – 248UDP-sugar bindingBy similarity4
Regioni281 – 507Accessory regionBy similarityAdd BLAST227
Regioni664 – 707Important for dimerizationBy similarityAdd BLAST44

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal domain mediates glycosyltransferase activity.By similarity
The C-terminal domain that mediates lysyl hydroxylase activity is also important for homodimerization.By similarity

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1971 Eukaryota
ENOG410Y4QU LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182728

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_022320_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q20679

KEGG Orthology (KO)

More...
KOi
K13647

Identification of Orthologs from Complete Genome Data

More...
OMAi
FDPDMAM

Database of Orthologous Groups

More...
OrthoDBi
194164at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q20679

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029044 Nucleotide-diphossugar_trans
IPR005123 Oxoglu/Fe-dep_dioxygenase
IPR006620 Pro_4_hyd_alph
IPR001006 Procol_lys_dOase

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00702 P4Hc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53448 SSF53448, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51471 FE2OG_OXY, 1 hit
PS01325 LYS_HYDROXYLASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q20679-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRVLPFLLPL IPVLLATTIT DLPELVVVTV ATENTDGLKR LLESAKAFDI
60 70 80 90 100
NIEVLGLGEK WNGGDTRIEQ GGGQKIRILS DWIEKYKDAS DTMIMFVDAY
110 120 130 140 150
DVVFNADSTT ILRKFFEHYS EKRLLFGAEP FCWPDQSLAP EYPIVEFGKR
160 170 180 190 200
FLNSGLFMGY GPEMHKILKL KSVEDKDDDQ LYYTMIYLDE KLRKELNMDL
210 220 230 240 250
DSMSKIFQNL NGVIEDVELQ FKEDGTPEAY NAAYNTKPLI VHGNGPSKSH
260 270 280 290 300
LNYLGNYLGN RWNSQLGCRT CGLEVKESEE VPLIALNLFI SKPIPFIEEV
310 320 330 340 350
LQKIAEFDYP KEKIALYIYN NQPFSIKNIQ DFLQKHGKSY YTKRVINGVT
360 370 380 390 400
EIGDREARNE AIEWNKARNV EFAFLMDGDA YFSEPKVIKD LIQYSKTYDV
410 420 430 440 450
GIIAPMIGQP GKLFTNFWGA IAANGYYARS EDYMAIVKGN RVGYWNVPFI
460 470 480 490 500
TSAVLFNKEK LEAMKDAYSY NKNLDPDMSM CKFARDNGHF LYIDNEKYYG
510 520 530 540 550
FLIVSDEYAE TVTEGKWHPE MWQIFENREL WEARYIHPGY HKIMEPEHVV
560 570 580 590 600
DQACPDVYDF PLMSERFCEE LIEEMEGFGR WSDGSNNDKR LAGGYENVPT
610 620 630 640 650
RDIHMNQVGF ERQWLYFMDT YVRPVQEKTF IGYYHQPVES NMMFVVRYKP
660 670 680 690 700
EEQPSLRPHH DASTFSIDIA LNKKGRDYEG GGVRYIRYNC TVPADEVGYA
710 720 730
MMFPGRLTHL HEGLATTKGT RYIMVSFINP
Length:730
Mass (Da):84,425
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i884F3EFE1A0A86FF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z66512 Genomic DNA Translation: CAA91321.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T22517

NCBI Reference Sequences

More...
RefSeqi
NP_496170.1, NM_063769.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F52H3.1.1; F52H3.1.1; WBGene00002497
F52H3.1.2; F52H3.1.2; WBGene00002497
F52H3.1.3; F52H3.1.3; WBGene00002497
F52H3.1.4; F52H3.1.4; WBGene00002497

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
174564

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F52H3.1

UCSC genome browser

More...
UCSCi
F52H3.1.1 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z66512 Genomic DNA Translation: CAA91321.1
PIRiT22517
RefSeqiNP_496170.1, NM_063769.3

3D structure databases

SMRiQ20679
ModBaseiSearch...

Protein-protein interaction databases

BioGridi39884, 1 interactor
STRINGi6239.F52H3.1.1

PTM databases

iPTMnetiQ20679

Proteomic databases

EPDiQ20679
PaxDbiQ20679
PeptideAtlasiQ20679
PRIDEiQ20679

Genome annotation databases

EnsemblMetazoaiF52H3.1.1; F52H3.1.1; WBGene00002497
F52H3.1.2; F52H3.1.2; WBGene00002497
F52H3.1.3; F52H3.1.3; WBGene00002497
F52H3.1.4; F52H3.1.4; WBGene00002497
GeneIDi174564
KEGGicel:CELE_F52H3.1
UCSCiF52H3.1.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
174564
WormBaseiF52H3.1 ; CE03397 ; WBGene00002497 ; let-268

Phylogenomic databases

eggNOGiKOG1971 Eukaryota
ENOG410Y4QU LUCA
GeneTreeiENSGT00950000182728
HOGENOMiCLU_022320_1_0_1
InParanoidiQ20679
KOiK13647
OMAiFDPDMAM
OrthoDBi194164at2759
PhylomeDBiQ20679

Enzyme and pathway databases

ReactomeiR-CEL-1650814 Collagen biosynthesis and modifying enzymes

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q20679

Gene expression databases

BgeeiWBGene00002497 Expressed in multi-cellular organism and 4 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR029044 Nucleotide-diphossugar_trans
IPR005123 Oxoglu/Fe-dep_dioxygenase
IPR006620 Pro_4_hyd_alph
IPR001006 Procol_lys_dOase
SMARTiView protein in SMART
SM00702 P4Hc, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit
PROSITEiView protein in PROSITE
PS51471 FE2OG_OXY, 1 hit
PS01325 LYS_HYDROXYLASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLOD_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q20679
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: February 26, 2020
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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