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Protein

Probable rho GDP-dissociation inhibitor

Gene

rhi-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.By similarity

GO - Molecular functioni

Keywordsi

Molecular functionGTPase activation

Enzyme and pathway databases

ReactomeiR-CEL-194840 Rho GTPase cycle

Names & Taxonomyi

Protein namesi
Recommended name:
Probable rho GDP-dissociation inhibitor
Short name:
Rho GDI
Gene namesi
Name:rhi-1
ORF Names:F46H6.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiF46H6.1 ; CE04595 ; WBGene00004356 ; rhi-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002190201 – 191Probable rho GDP-dissociation inhibitorAdd BLAST191

Proteomic databases

EPDiQ20496
PaxDbiQ20496
PeptideAtlasiQ20496
PRIDEiQ20496

PTM databases

iPTMnetiQ20496

Expressioni

Gene expression databases

BgeeiWBGene00004356
ExpressionAtlasiQ20496 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi6239.F46H6.1.3

Structurei

3D structure databases

ProteinModelPortaliQ20496
SMRiQ20496
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Rho GDI family.Curated

Phylogenomic databases

eggNOGiKOG3205 Eukaryota
ENOG4111K44 LUCA
GeneTreeiENSGT00390000006233
HOGENOMiHOG000175765
InParanoidiQ20496
KOiK12462
OMAiSYPPKKE
OrthoDBiEOG091G0MBU
PhylomeDBiQ20496

Family and domain databases

Gene3Di2.70.50.30, 1 hit
InterProiView protein in InterPro
IPR014756 Ig_E-set
IPR000406 Rho_GDI
IPR024792 RhoGDI_dom_sf
PANTHERiPTHR10980 PTHR10980, 1 hit
PfamiView protein in Pfam
PF02115 Rho_GDI, 1 hit
PRINTSiPR00492 RHOGDI
SUPFAMiSSF81296 SSF81296, 1 hit

Sequencei

Sequence statusi: Complete.

Q20496-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDHENTGEN TSEYQYKQPP QKSIDELLNA DKEDESLKVY KAKLLGQGTV
60 70 80 90 100
IVDEKNPLRV IVRSVELLIN GKTAQSFDLS DPAKLVNSDL SVSIKEGSNY
110 120 130 140 150
RLSFAFHVQR EITSGLHYKH KVKRSGITVE NEKYMMGSYA PKLEIQEYKS
160 170 180 190
PNEEAPSGMM HRGKYKVYSK ITDDDNNVYL DWQWTLHITK E
Length:191
Mass (Da):21,919
Last modified:November 1, 1997 - v1
Checksum:i66A5B84ED0BCD450
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080405 Genomic DNA Translation: CCD63475.1
PIRiT16379
RefSeqiNP_508774.1, NM_076373.5
UniGeneiCel.19607

Genome annotation databases

EnsemblMetazoaiF46H6.1; F46H6.1; WBGene00004356
GeneIDi180721
KEGGicel:CELE_F46H6.1
UCSCiF46H6.1.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiGDIR_CAEEL
AccessioniPrimary (citable) accession number: Q20496
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 22, 2017
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

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