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Entry version 114 (11 Dec 2019)
Sequence version 4 (06 Feb 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

CELE_F35A5.1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CELE_F35A5.1Imported, F35A5.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
F35A5.1 ; CE48053 ; WBGene00018024

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q20007

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q20007

PeptideAtlas

More...
PeptideAtlasi
Q20007

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00018024 Expressed in 4 organ(s), highest expression level in material anatomical entity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.F35A5.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 2030DisorderedSequence analysisAdd BLAST2030

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi34 – 51PolyampholyteSequence analysisAdd BLAST18
Compositional biasi98 – 123PolyampholyteSequence analysisAdd BLAST26
Compositional biasi142 – 195PolyampholyteSequence analysisAdd BLAST54
Compositional biasi211 – 242PolyampholyteSequence analysisAdd BLAST32
Compositional biasi279 – 315PolyampholyteSequence analysisAdd BLAST37
Compositional biasi332 – 346Pro-richSequence analysisAdd BLAST15
Compositional biasi349 – 379PolyampholyteSequence analysisAdd BLAST31
Compositional biasi450 – 473PolyampholyteSequence analysisAdd BLAST24
Compositional biasi481 – 501PolyampholyteSequence analysisAdd BLAST21
Compositional biasi521 – 574PolyampholyteSequence analysisAdd BLAST54
Compositional biasi589 – 619PolyampholyteSequence analysisAdd BLAST31
Compositional biasi656 – 670Pro-richSequence analysisAdd BLAST15
Compositional biasi672 – 688PolyampholyteSequence analysisAdd BLAST17
Compositional biasi737 – 756Pro-richSequence analysisAdd BLAST20
Compositional biasi779 – 793Pro-richSequence analysisAdd BLAST15
Compositional biasi818 – 836PolyampholyteSequence analysisAdd BLAST19
Compositional biasi870 – 887Pro-richSequence analysisAdd BLAST18
Compositional biasi889 – 958PolyampholyteSequence analysisAdd BLAST70
Compositional biasi1008 – 1022PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1036 – 1051Pro-richSequence analysisAdd BLAST16
Compositional biasi1111 – 1157PolyampholyteSequence analysisAdd BLAST47
Compositional biasi1175 – 1218PolyampholyteSequence analysisAdd BLAST44
Compositional biasi1245 – 1297PolyampholyteSequence analysisAdd BLAST53
Compositional biasi1324 – 1344PolyampholyteSequence analysisAdd BLAST21
Compositional biasi1352 – 1376PolyampholyteSequence analysisAdd BLAST25
Compositional biasi1406 – 1458PolyampholyteSequence analysisAdd BLAST53
Compositional biasi1483 – 1535PolyampholyteSequence analysisAdd BLAST53
Compositional biasi1565 – 1617PolyampholyteSequence analysisAdd BLAST53
Compositional biasi1647 – 1699PolyampholyteSequence analysisAdd BLAST53
Compositional biasi1729 – 1800PolyampholyteSequence analysisAdd BLAST72
Compositional biasi1811 – 1883PolyampholyteSequence analysisAdd BLAST73
Compositional biasi1893 – 1956PolyampholyteSequence analysisAdd BLAST64
Compositional biasi1974 – 1992AcidicSequence analysisAdd BLAST19

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JAEZ Eukaryota
ENOG411151U LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161893

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000213121

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q20007

Identification of Orthologs from Complete Genome Data

More...
OMAi
PWEDDPD

Database of Orthologous Groups

More...
OrthoDBi
1044778at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033183 NF-H

The PANTHER Classification System

More...
PANTHERi
PTHR23214 PTHR23214, 13 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q20007-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRAPPTPIK NPAKKWKPPW ESVDEEEEME VDEETPAPSK LEKKPSLKRK
60 70 80 90 100
DAPTKPVPSP GAPSPVPIKN PVKKWKAPWE DDEPMEEAPA APVPAKKVRD
110 120 130 140 150
PSPKKVPAKP RDASPKKIMA AKKEPETLPA VPPTPVKNPV KKFKAPWEDD
160 170 180 190 200
EVDVEDVKDA PTVPAKKTPV LKKKEPAAAA KPRDPSPKKA APSKEHDPIV
210 220 230 240 250
PPTPIKNPAK KWKPPWEDDE VPTEEIKEPE PATRKVPALK KKEPSTSVKP
260 270 280 290 300
VSDPSPTKKV PVKKEPEVPP TPIKNPTKKW KPPWEDETPV EEVKEPPVPE
310 320 330 340 350
KKAPVLKKKD PAPAAKARDP SPSKAAPKKV EPSSPVVPPT PVKNPVKKYK
360 370 380 390 400
PPWEVDDEPA EEVKKPSAPE KKTPVLKRKE PEPSSTTPSS DPSPKKAAPA
410 420 430 440 450
VKPRDSSPKK ATPLQADPKA QEVPPTPVKN PVKKYKPPWE VDDEDPVEEV
460 470 480 490 500
KQPEAPAKKT PVLKRKEPAA KDTAKPATSK TPETPEKKDP VKPRDSSPKK
510 520 530 540 550
VAAKPDSAQA PATPVKNPVK KWRPPWEDDE TPADDVSKPT DAKKTPSLAK
560 570 580 590 600
KDPAPAKESL KPKADTKAPA KPRDPSPKKV APTAPEKKTP VLAKKEPAGP
610 620 630 640 650
ADSKTKEPEK SKPRDPSPKK AVPAKPVPKT EVAPAAVKKP EPISKPKDTA
660 670 680 690 700
PKKAEPNSPV VPPTPVKNPV KKWKPPWEDD DAPAKPVSLP EPEKKTPVLA
710 720 730 740 750
KKAPTKPDSE AAADPVSGPS SKDPKLAKKA PVKPRDPSPM KAVPIKPAPK
760 770 780 790 800
TEVPPAVVKK PEPVAKSRDP SPKKAKAEPN SPVVPPTPVK NPVKKWKPPW
810 820 830 840 850
EDDDAPAEPV NVPEPEKKTP VLAKKTPVKP RDPSPKKAVP AKPSTKTDAP
860 870 880 890 900
PVSVKKPEPV SKPKEPSPKK AEPNSPVVPP TPVKNPVKKW KPPWEDDDEP
910 920 930 940 950
TEEVKKPSEP EKKTPVLAKK EPEKPKDAPK VAAKPRDPSP KKAVPEKEPA
960 970 980 990 1000
KVAAKPRDLS PKKAIPIPAN TQEAPPTPVK NPVKKWKPPW EDDDEPAEPV
1010 1020 1030 1040 1050
SAPEPEKKTP VLAKKAPAKP RDPSPKKAAP VAAKPDPKIP EVPPTPVKNP
1060 1070 1080 1090 1100
VKKWKPPWED DDEPSEPVSA PEPEKKTPVL AKKAPTKPAT KPDSEAAADP
1110 1120 1130 1140 1150
VSGPTSKDPK LSKKAPVEKP KPTTDPKDDK LKPSPAKKPE KAPEPAAPKK
1160 1170 1180 1190 1200
WKPVWDDDPD EPEADFTVPA PSKKPDTEDP ADPLGGPKTK DPKLNKKAPA
1210 1220 1230 1240 1250
EKPTEKPKPK EVSKEPPKPT EPPKPAAPKK WKPPWEDDPD EPEADFTMPA
1260 1270 1280 1290 1300
PKKPDTEDPA DSLGGPKPKD PKLAKKAPAK KPTETPKPKE VPKEPPKAAE
1310 1320 1330 1340 1350
PPKPAAPKKW KPPWEDDPDE PEADFTMPAP KKPDSEDPAD SLGGPKPKDP
1360 1370 1380 1390 1400
KLASKAPAKK PSETPKPKEV PKELPKPAEP SKPAAPKKWR PPWEDDPDEP
1410 1420 1430 1440 1450
EEPEADFTMP APKKPDTEDP ADSLGGPKPK DPKLAKKAPA KKPTETLKPK
1460 1470 1480 1490 1500
DAPKEPPKPA DPPKPAALKK PPWEDDPDEP EADFTMPAPK KPDTEDLADP
1510 1520 1530 1540 1550
PGGPKPKDPK LAKKAPAKKP SETPKPEDAP KEPPKPAEPP KPAAPKKWKP
1560 1570 1580 1590 1600
PWEEDPDEPE EPEADFTMPT PKKPDTEDPA DPLGRPKPKD PKLAKKAPAK
1610 1620 1630 1640 1650
KPSETPKPKD APKEPPKPAE PPKPAAPKKW KPPWEEDPDE PEEPEADYTM
1660 1670 1680 1690 1700
PAPKKPDTED PADPLGGPKP KDPKLAKKAP AKKPTDKPKS KDVPKEAPKP
1710 1720 1730 1740 1750
AEPPKPAAPK KWKPPWEEDP DEPEEPEADF TMPAPKKPDT EDPADPLGGP
1760 1770 1780 1790 1800
KKKDPKLAKK APSKKPTDKP KPKDLPKEEP KPAEPPKPAA PKKWKPPWEE
1810 1820 1830 1840 1850
DPDEPEEPEA DFTMPAPKKP DTEDPADPLG GPKKKDPKLA KKAPAKKPTD
1860 1870 1880 1890 1900
KPKPKDAPKD AKPTPEEPAK PVAPKKWKPP WEEDPDEPEE PEADFTMPAK
1910 1920 1930 1940 1950
KKPDTEDPAD PLGGPNKKDP KLAKKAPTKK PADKPKPSEE PEKPVAPKKW
1960 1970 1980 1990 2000
KPPWEEDPDD EPEADFTVPI KPGEDEDEPE DADDEEEPED EPAEDEPKKK
2010 2020 2030 2040 2050
KPKKHRKRPK KKKPVVEPEK EPTPEPVVPK APKWIAPIKK PEEPIPMPPK
2060 2070 2080 2090 2100
EKTIAERNKE ERIPPALRYA KKPRELEVYI PFVIPWEQTA ALITQEGMGA
2110 2120 2130 2140 2150
FGKSRAANVE VNFGDKPIVQ GAVDSKTVIP LWNDESKCAN RSGMTAFGAP
2160 2170 2180 2190 2200
REIDQNVVDH HVFNLMDKGK SQGIIPLLAK GTTYHPHGEY GTIRRQTADV
2210 2220 2230 2240 2250
KYKDGWKPGM DSESHGFISR QFIANSKEKA GSNLLDKRRT IISDALPQSK
2260 2270 2280 2290 2300
ECEAMIPLMF DGRAVETREG SEFGSFRPLV TNATGGYLMS YADEMKCKNI
2310
IPFQTAPSLV R
Length:2,311
Mass (Da):252,478
Last modified:February 6, 2013 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5C3F7F6F90C7DAE1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD70484.2

NCBI Reference Sequences

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RefSeqi
NP_508662.4, NM_076261.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F35A5.1.1; F35A5.1.1; WBGene00018024

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
259699

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F35A5.1

UCSC genome browser

More...
UCSCi
F35A5.1 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CCD70484.2
RefSeqiNP_508662.4, NM_076261.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi6239.F35A5.1

Proteomic databases

EPDiQ20007
PaxDbiQ20007
PeptideAtlasiQ20007

Genome annotation databases

EnsemblMetazoaiF35A5.1.1; F35A5.1.1; WBGene00018024
GeneIDi259699
KEGGicel:CELE_F35A5.1
UCSCiF35A5.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
259699
WormBaseiF35A5.1 ; CE48053 ; WBGene00018024

Phylogenomic databases

eggNOGiENOG410JAEZ Eukaryota
ENOG411151U LUCA
GeneTreeiENSGT00940000161893
HOGENOMiHOG000213121
InParanoidiQ20007
OMAiPWEDDPD
OrthoDBi1044778at2759

Gene expression databases

BgeeiWBGene00018024 Expressed in 4 organ(s), highest expression level in material anatomical entity

Family and domain databases

InterProiView protein in InterPro
IPR033183 NF-H
PANTHERiPTHR23214 PTHR23214, 13 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ20007_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q20007
Secondary accession number(s): G4SGM2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: February 6, 2013
Last modified: December 11, 2019
This is version 114 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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