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Protein
Submitted name:

RE42507p

Gene

stumps

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DME-1257604 PIP3 activates AKT signaling
R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-DME-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Names & Taxonomyi

Protein namesi
Submitted name:
RE42507pImported
Submitted name:
Stumps, isoform CImported
Gene namesi
Name:stumpsImported
Synonyms:0837Imported, 10Imported, anon-EST:CL47Imported, anon-estCImported, CImported, CG18485Imported, CG3375Imported, Dmel\CG31317Imported, DOFImported, DofImported, dofImported, dof1Imported, gene CImported, HbrImported, hbrImported, heartbrokenImported, i21Imported, i28Imported, l(3)09904Imported, l(3)S083710Imported, P1740Imported, smsImported
ORF Names:CG31317Imported, Dmel_CG31317Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0020299 stumps

Subcellular locationi

Expressioni

Gene expression databases

BgeeiFBgn0020299 Expressed in 48 organ(s), highest expression level in embryo

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0111806

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini415 – 552DBBInterPro annotationAdd BLAST138

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili904 – 938Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IKKC Eukaryota
ENOG4110NCP LUCA
GeneTreeiENSGT00390000008787
OrthoDBiEOG091G0125

Family and domain databases

InterProiView protein in InterPro
IPR017893 DBB_domain
PfamiView protein in Pfam
PF14545 DBB, 1 hit
SMARTiView protein in SMART
SM01282 DBB, 1 hit
PROSITEiView protein in PROSITE
PS51376 DBB, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q1WWH6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVDNPYYFC NETKSPRTPD SQSSSRGFSI FKRRNSKGSS PRPLVMTNPE
60 70 80 90 100
QMRLITSANL DTTATMALGS PRGSFNSLAG YPQHAIELQT MNMYRQRSAN
110 120 130 140 150
SHSEFRERLN SCNETHSSQC PGGGGASVAG DHDEVFNPLT SPTSSKSHRH
160 170 180 190 200
HTLPSGGTRR HSLGNWAQHQ HQQQHQQNSG AMGLGSPDEV PSMMAPRPPL
210 220 230 240 250
LSPNKFRGSS HRRRDNCGNV NNTSGSSASG FLGSPGYNMD DILIITAKHS
260 270 280 290 300
ERAYLRATFL KNHFDKITKQ RGRKPFNFLH IKIDDGPFSE EIAHKYQNTA
310 320 330 340 350
LQIVILCPAL LALPHSFLMT QLSAIIRVEK VLAILLDVSE EKVKEMHKSA
360 370 380 390 400
LPSYYKWRRC VVRDNDQVQI SNILGIATDI LGRALCQRPP CQDSSGGGGG
410 420 430 440 450
GLSRSFSSCT EGFTVLPKKV KLGQNKVVAL LAEPLEKNDT LKLQVEKSGE
460 470 480 490 500
LIELRNFKCR NPYTLQFNIP EACMEISTMI EIRIEKNNKS LGARPIKCES
510 520 530 540 550
RLRELEQLLR IEDSPIEFMC HALGIGPVER DALDQHLLQC FQRNMPPNFH
560 570 580 590 600
LLSGPSERQP HFFTRLESSP EEYPTLLHFA ARWGLNRLCI QLMECPGGDT
610 620 630 640 650
ACGVRNCAGR TPAELAEQEG HHKLAQNIVS FAEFHELTTM YHYFKGVTPP
660 670 680 690 700
GESCPKPSAN VVIEAHPVKA GKTNKPPKEL PTAEYMEMSS GSERENTPEV
710 720 730 740 750
RTKTETLAIS NLNYISVETE DENLQASVAE KKVESEKKLP EAGNQPGPEK
760 770 780 790 800
TTNELRINEP PYYQSKEQNQ QPKELKNQSK SLDEVDAAPL YQTDKFSQEC
810 820 830 840 850
SQLLENQLGN DYVLQPSNVP VAQDDGNYLF QPSNRPVEEP LRLNRCTNRQ
860 870 880 890 900
PGYGTLKRSA SDASAASHTR SNADDELAEI MHDFKNNVLS IRDVEVLVER
910 920 930 940 950
WKHRNDVQQS FREKQDQIDQ LRREYERIQE QVKSHLKRET PFERIKKFFL
960 970 980 990 1000
RSKTPGGNDS LLDETKSSIA TSCSFKSAGG VSSSAGAGRP ISSLSLQSVS
1010 1020 1030 1040 1050
SSSSSSGRLS TGSNCSGASL GDSGTHSDHE DRRFPHCRMM DNYMVPPTPR
1060 1070 1080 1090 1100
PVFTPSSTPG DERHQIVFPS PMSSCQRLNT PTSPTGSEHY QMFPSNIPVY
1110 1120 1130 1140 1150
GSQPLVGSQS SNYLNTIMEA KEQAETQHYQ NQNGVTLQPI KLNERSNIIY
1160 1170 1180 1190 1200
GKLTKSSSAS GCSSFKPKQI PVPCPQVGSI EVQAEVYQNV GDVAPEKDSK
1210
AEEETPNYMN C
Length:1,211
Mass (Da):134,707
Last modified:May 2, 2006 - v1
Checksum:i585615383AA17F3E
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9VFI0Q9VFI0_DROME
Stumps, isoform E
stumps 0837, 10, anon-EST:CL47, anon-estC, C stumps 0837, 10, anon-EST:CL47, anon-estC, C, CG18485, CG31317, CG3375, Dmel\CG31317, DOF, Dof, dof, dof1, gene C, Hbr, hbr, heartbroken, i21, i28, l(3)09904, l(3)S083710, P1740, sms, CG31317, Dmel_CG31317
1,220Annotation score:
Q9VFH9Q9VFH9_DROME
Stumps, isoform B
stumps 0837, 10, anon-EST:CL47, anon-estC, C stumps 0837, 10, anon-EST:CL47, anon-estC, C, CG18485, CG31317, CG3375, Dmel\CG31317, DOF, Dof, dof, dof1, gene C, Hbr, hbr, heartbroken, i21, i28, l(3)09904, l(3)S083710, P1740, sms, CG31317, Dmel_CG31317
1,012Annotation score:
A0A0B4KGP0A0A0B4KGP0_DROME
Stumps, isoform F
stumps 0837, 10, anon-EST:CL47, anon-estC, C stumps 0837, 10, anon-EST:CL47, anon-estC, C, CG18485, CG31317, CG3375, Dmel\CG31317, DOF, Dof, dof, dof1, gene C, Hbr, hbr, heartbroken, i21, i28, l(3)09904, l(3)S083710, P1740, sms, CG31317, Dmel_CG31317
973Annotation score:
A0A0B4KFZ6A0A0B4KFZ6_DROME
Stumps, isoform D
stumps 0837, 10, anon-EST:CL47, anon-estC, C stumps 0837, 10, anon-EST:CL47, anon-estC, C, CG18485, CG31317, CG3375, Dmel\CG31317, DOF, Dof, dof, dof1, gene C, Hbr, hbr, heartbroken, i21, i28, l(3)09904, l(3)S083710, P1740, sms, CG31317, Dmel_CG31317
1,029Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT024930 mRNA Translation: ABE01160.1
AE014297 Genomic DNA Translation: ABW08674.1
RefSeqiNP_001097792.1, NM_001104322.2
UniGeneiDm.1198

Genome annotation databases

EnsemblMetazoaiFBtr0112893; FBpp0111806; FBgn0020299
GeneIDi41770
KEGGidme:Dmel_CG31317
UCSCiCG31317-RC d. melanogaster

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT024930 mRNA Translation: ABE01160.1
AE014297 Genomic DNA Translation: ABW08674.1
RefSeqiNP_001097792.1, NM_001104322.2
UniGeneiDm.1198

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0111806

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0112893; FBpp0111806; FBgn0020299
GeneIDi41770
KEGGidme:Dmel_CG31317
UCSCiCG31317-RC d. melanogaster

Organism-specific databases

CTDi41770
FlyBaseiFBgn0020299 stumps

Phylogenomic databases

eggNOGiENOG410IKKC Eukaryota
ENOG4110NCP LUCA
GeneTreeiENSGT00390000008787
OrthoDBiEOG091G0125

Enzyme and pathway databases

ReactomeiR-DME-1257604 PIP3 activates AKT signaling
R-DME-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-DME-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Miscellaneous databases

GenomeRNAii41770

Gene expression databases

BgeeiFBgn0020299 Expressed in 48 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR017893 DBB_domain
PfamiView protein in Pfam
PF14545 DBB, 1 hit
SMARTiView protein in SMART
SM01282 DBB, 1 hit
PROSITEiView protein in PROSITE
PS51376 DBB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ1WWH6_DROME
AccessioniPrimary (citable) accession number: Q1WWH6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 2, 2006
Last sequence update: May 2, 2006
Last modified: October 10, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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