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UniProtKB - Q1W617 (SHRM4_MOUSE)

Entry version 104 (12 Aug 2020)
Sequence version 1 (02 May 2006)
Previous versions | rss
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Protein

Protein Shroom4

Gene

Shroom4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding, Developmental protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein Shroom4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Shroom4
Synonyms:Kiaa1202
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2685570, Shroom4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002870781 – 1475Protein Shroom4Add BLAST1475

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei412PhosphoserineCombined sources1
Modified residuei722PhosphoserineCombined sources1
Modified residuei1010PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q1W617

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q1W617

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q1W617

PeptideAtlas

More...PeptideAtlasi		Q1W617

PRoteomics IDEntifications database

More...PRIDEi		Q1W617

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q1W617

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q1W617

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in most adult tissues examined. Expressed in brain, lung, heart, liver, kidney, muscle and ovary. Expressed throughout the brain, with high expression in the brain stem and cerebellum and weaker expression in the hypothalamus, the hippocampus and the olfactory bulb. Expressed in wide range of cell types during developpment, including vascular endothelium and the polarized epithelium of the neural tube and kidney.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Slight expression at 8.5 dpc, increasing till 11.5 dpc and remaining continuous thereafter, suggesting regulated expression during development.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000068270, Expressed in placenta and 205 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q1W617, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q1W617, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts directly with F-actin.

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		228981, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000100070

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q1W617, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q1W617

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 92PDZPROSITE-ProRule annotationAdd BLAST83
Domaini1190 – 1469ASD2PROSITE-ProRule annotationAdd BLAST280

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1380 – 1470Sequence analysisAdd BLAST91

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi862 – 929Cys-richAdd BLAST68
Compositional biasi1091 – 1098Poly-Pro8
Compositional biasi1110 – 1187Gln-richAdd BLAST78

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the shroom family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QUU2, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159479

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_003220_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q1W617

KEGG Orthology (KO)

More...KOi		K18625

Identification of Orthologs from Complete Genome Data

More...OMAi		KPLHCSD

Database of Orthologous Groups

More...OrthoDBi		29607at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q1W617

TreeFam database of animal gene trees

More...TreeFami		TF333370

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.42.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR014799, ASD2_dom
IPR001478, PDZ
IPR036034, PDZ_sf
IPR027687, Shroom4
IPR027685, Shroom_fam

The PANTHER Classification System

More...PANTHERi		PTHR15012, PTHR15012, 1 hit
PTHR15012:SF35, PTHR15012:SF35, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08687, ASD2, 1 hit
PF00595, PDZ, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00228, PDZ, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50156, SSF50156, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51307, ASD2, 1 hit
PS50106, PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q1W617-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESRPGSFQY VPVQLQGGAP WGFTLKGGLE HCEPLTVSKI EDGGKAALSQ 
        60         70         80         90        100
KMRTGDELVN INGTPLYGSR QEALILIKGS FRILKLIVRR RNTPVSRPHS 
       110        120        130        140        150
WHVAKLLEGC PDVATTMHFP SEAFSLSWHS GCNTSDVSVQ WCPLSRHCST 
       160        170        180        190        200
EKSSSIGSME SLEQPGQPTY EGHLLPIDQN MYPSQRDSAY SSFSASSNAS 
       210        220        230        240        250
DCALSLKPEE PPSTDCVMPG PGPIKVTDDQ ANVSENSGSS HSTSEDHVTS 
       260        270        280        290        300
TSHASSYSDE GHHSGPAKMA RGPPEPPVRS DSLPASRAQL LNGEQHRASE 
       310        320        330        340        350
PVDSLPQKEK PGLETVLPPR SSNQFCCLSG QDQVTDEDHQ NCELSKPSES 
       360        370        380        390        400
SQDDCEHLLI EDSSKALDSP KAHDKGSNKE FGLLKEASAD LANTLNFGAI 
       410        420        430        440        450
PHLRGTMEHR HSAPEQLLAS HLQQVHLDSR GSKGMELPIG QDGHQWTVSP 
       460        470        480        490        500
LHNNPKGKKS PSLPTGGTQD QTRKERKTTP LDDKLMASVH QSQSDVLLGE 
       510        520        530        540        550
VDGHPNRAGR ASSDLTSQQP SATCSSVQQT RDFLSAHKIV DHTEASEEGD 
       560        570        580        590        600
NEPKECGRLG GRRSGGPRGR SIQNRRRSER FATNLRNEIQ RRKAQLQKSK 
       610        620        630        640        650
GPLSQLCDTN EAVEETQEPP ESPPLSASNA SLLPSYKNVP SPGDKVFNKS 
       660        670        680        690        700
MILRARSSEC LSQASESSKA RGGVEGRMSP GQRSGQSSLA LNTWWKASDS 
       710        720        730        740        750
STLDTEKANA HHGVCRGHWR WSPEHNAQPQ VALSTEAPSN PDDSKELKTS 
       760        770        780        790        800
TPQAGEEAVL MPFADRRKFF EESSKSLSTS HLPGLTTHNN KPFIQRQKPI 
       810        820        830        840        850
DQNFQSVSYR DLRCHPLDQS YHSADQSYHA ADQSYHSLSP LQSETPTYPE 
       860        870        880        890        900
CFATKGRDNS LCCKPVHHGD CDYHRTCSHP CSAQGTVRHD PCICCSGEIC 
       910        920        930        940        950
PALLKRNLLP KCHNCRCHHH QCIRCTGCCH GPQHSAHEDS SMAPGNAWKS 
       960        970        980        990       1000
RKAAIQEFPV DKWKPITGNR KTSHSGREMA HSKAGFSLST PFRPCIENPA 
      1010       1020       1030       1040       1050
LDLSNYRAVS SLDILGDFKR ASNKPEESSV YEDENSVASM PRPLRSRAFS 
      1060       1070       1080       1090       1100
ESHISLEPQN TQAWGKHQRE SFSKGSETQP DTLGARKKVF PPPRPPPPNW 
      1110       1120       1130       1140       1150
EKYRLFRAAQ LQQQQQQQQQ QQQQQRCEEE EEKEQEEEGE KEEDLPPQYF 
      1160       1170       1180       1190       1200
SSELTGSCAP NTEEQPQSLK MGHQEASRQG SQSLQEQEAF ALHPSNFVPP 
      1210       1220       1230       1240       1250
VRGCTVPQPE KAQHPCYYGT HGLWRTTEQE ATVTPKQEFQ HFSPPKGASG 
      1260       1270       1280       1290       1300
IPTSYSAYYN ISVAKAELLN KLKQQPEMAE AGLGEEGVDY ELAQKKIQLI 
      1310       1320       1330       1340       1350
ESISRKLSVL REAQRGLLDD INANAALGEE VEANLKAVCK SNEFEKYHLF 
      1360       1370       1380       1390       1400
IGDLDKVVNL LLSLSGRLAR VENALNSIDS ESNQEKLVLI EKKQQLTNQL 
      1410       1420       1430       1440       1450
ADAKELKEHV DGREKLVFGM VSRYLPQDQL QDYQHFVKMK SALIIEQREL 
      1460       1470 
EEKIKLGEEQ LKCLKESLHL GPSNF
Length:1,475
Mass (Da):163,238
Last modified:May 2, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iACDB38FAB87F48B9
GO
Isoform 2 (identifier: Q1W617-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-116: Missing.

Show »
Length:1,359
Mass (Da):150,547
Checksum:i89FC8DF5C6A9CBB9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PUX3E9PUX3_MOUSE
Protein Shroom4
Shroom4
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD32407 differs from that shown. Reason: Erroneous initiation.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0252911 – 116Missing in isoform 2. 1 PublicationAdd BLAST116

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
DQ435686 mRNA Translation: ABD98016.1
DQ435687 mRNA Translation: ABD98017.1
AK173129 mRNA Translation: BAD32407.1 Different initiation.
AL671501 Genomic DNA No translation available.
BC151022 mRNA Translation: AAI51023.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS29959.1 [Q1W617-1]
CCDS85744.1 [Q1W617-2]

NCBI Reference Sequences

More...RefSeqi		NP_001035549.1, NM_001040459.2 [Q1W617-1]
NP_001300693.1, NM_001313764.1
NP_001300694.1, NM_001313765.1 [Q1W617-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000089520; ENSMUSP00000086949; ENSMUSG00000068270 [Q1W617-2]
ENSMUST00000103005; ENSMUSP00000100070; ENSMUSG00000068270 [Q1W617-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		208431

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:208431

UCSC genome browser

More...UCSCi		uc009sky.1, mouse [Q1W617-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ435686 mRNA Translation: ABD98016.1
DQ435687 mRNA Translation: ABD98017.1
AK173129 mRNA Translation: BAD32407.1 Different initiation.
AL671501 Genomic DNA No translation available.
BC151022 mRNA Translation: AAI51023.1
CCDSiCCDS29959.1 [Q1W617-1]
CCDS85744.1 [Q1W617-2]
RefSeqiNP_001035549.1, NM_001040459.2 [Q1W617-1]
NP_001300693.1, NM_001313764.1
NP_001300694.1, NM_001313765.1 [Q1W617-2]

3D structure databases

SMRiQ1W617
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi228981, 1 interactor
STRINGi10090.ENSMUSP00000100070

PTM databases

iPTMnetiQ1W617
PhosphoSitePlusiQ1W617

Proteomic databases

jPOSTiQ1W617
MaxQBiQ1W617
PaxDbiQ1W617
PeptideAtlasiQ1W617
PRIDEiQ1W617

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		532, 13 antibodies

Genome annotation databases

EnsembliENSMUST00000089520; ENSMUSP00000086949; ENSMUSG00000068270 [Q1W617-2]
ENSMUST00000103005; ENSMUSP00000100070; ENSMUSG00000068270 [Q1W617-1]
GeneIDi208431
KEGGimmu:208431
UCSCiuc009sky.1, mouse [Q1W617-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		57477
MGIiMGI:2685570, Shroom4

Rodent Unidentified Gene-Encoded large proteins database

More...Rougei		Search...

Phylogenomic databases

eggNOGiENOG502QUU2, Eukaryota
GeneTreeiENSGT00940000159479
HOGENOMiCLU_003220_1_1_1
InParanoidiQ1W617
KOiK18625
OMAiKPLHCSD
OrthoDBi29607at2759
PhylomeDBiQ1W617
TreeFamiTF333370

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		208431, 1 hit in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Shroom4, mouse

Protein Ontology

More...PROi		PR:Q1W617
RNActiQ1W617, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000068270, Expressed in placenta and 205 other tissues
ExpressionAtlasiQ1W617, baseline and differential
GenevisibleiQ1W617, MM

Family and domain databases

Gene3Di2.30.42.10, 1 hit
InterProiView protein in InterPro
IPR014799, ASD2_dom
IPR001478, PDZ
IPR036034, PDZ_sf
IPR027687, Shroom4
IPR027685, Shroom_fam
PANTHERiPTHR15012, PTHR15012, 1 hit
PTHR15012:SF35, PTHR15012:SF35, 1 hit
PfamiView protein in Pfam
PF08687, ASD2, 1 hit
PF00595, PDZ, 1 hit
SMARTiView protein in SMART
SM00228, PDZ, 1 hit
SUPFAMiSSF50156, SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS51307, ASD2, 1 hit
PS50106, PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSHRM4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1W617
Secondary accession number(s): A2ADV9, B2RX74, Q69ZN9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 2, 2006
Last modified: August 12, 2020
This is version 104 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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