Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein Wnt

Gene

wnt4a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:wnt4aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-352 wnt4a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501013660123 – 352Protein WntSequence analysisAdd BLAST330

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000071208 Expressed in 35 organ(s), highest expression level in neural rod
ExpressionAtlasiQ1RLW9 baseline

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ1RLW9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
HOVERGENiHBG001595
KOiK00408
OMAiNSQFKPH
OrthoDBiEOG091G0OFF

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR009142 Wnt4
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01844 WNT4PROTEIN
PR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit

Sequencei

Sequence statusi: Complete.

Q1RLW9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSEYLIRSL LMLFLALFSA NASNWLYLAK LSSVGSISDE ETCEKLRGLI
60 70 80 90 100
QRQVQICKRN VEVMDAVRRG AQLAIDECQY QFRNRRWNCS TLESVPVFGK
110 120 130 140 150
VVTQGTREAA FVYAISAASV AFAVTRACSS GELDKCGCDR NVHGVSPEGF
160 170 180 190 200
QWSGCSDNIA YGVAFSQSFV DIRERSKGQS SNRALMNLHN NEAGRKAILN
210 220 230 240 250
HMRVECKCHG VSGSCEVKTC WKAMPPFRKV GNVIKEKFDG ATEVELRKVG
260 270 280 290 300
TTKVLVPRNS QFKPHTDEDL VYLDPSPDFC EHDPRTPGIM GTAGRFCNKT
310 320 330 340 350
SKAIDGCELM CCGRGFHTEE VEVVDRCSCK FHWCCYVKCK QCRKMVEMHT

CR
Length:352
Mass (Da):39,431
Last modified:May 16, 2006 - v1
Checksum:iD63CBF9F00886633
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC115247 mRNA Translation: AAI15248.1
BC163457 mRNA Translation: AAI63457.1
BC163474 mRNA Translation: AAI63474.1
RefSeqiNP_001035477.1, NM_001040387.1
UniGeneiDr.385

Genome annotation databases

GeneIDi30123
KEGGidre:30123

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC115247 mRNA Translation: AAI15248.1
BC163457 mRNA Translation: AAI63457.1
BC163474 mRNA Translation: AAI63474.1
RefSeqiNP_001035477.1, NM_001040387.1
UniGeneiDr.385

3D structure databases

SMRiQ1RLW9
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30123
KEGGidre:30123

Organism-specific databases

CTDi30123
ZFINiZDB-GENE-980526-352 wnt4a

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
HOVERGENiHBG001595
KOiK00408
OMAiNSQFKPH
OrthoDBiEOG091G0OFF

Gene expression databases

BgeeiENSDARG00000071208 Expressed in 35 organ(s), highest expression level in neural rod
ExpressionAtlasiQ1RLW9 baseline

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR009142 Wnt4
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01844 WNT4PROTEIN
PR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ1RLW9_DANRE
AccessioniPrimary (citable) accession number: Q1RLW9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 16, 2006
Last sequence update: May 16, 2006
Last modified: September 12, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again