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Protein

Tyrosine recombinase XerD

Gene

xerD

Organism
Rickettsia bellii (strain RML369-C)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei145UniRule annotation1
Active sitei175UniRule annotation1
Active sitei250UniRule annotation1
Active sitei253UniRule annotation1
Active sitei276UniRule annotation1
Active sitei285O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processCell cycle, Cell division, Chromosome partition, DNA integration, DNA recombination

Enzyme and pathway databases

BioCyciRBEL336407:G1G4P-1445-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine recombinase XerDUniRule annotation
Gene namesi
Name:xerDUniRule annotation
Ordered Locus Names:RBE_1002
OrganismiRickettsia bellii (strain RML369-C)
Taxonomic identifieri336407 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
Proteomesi
  • UP000001951 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002723681 – 305Tyrosine recombinase XerDAdd BLAST305

Interactioni

Subunit structurei

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1RHT1
SMRiQ1RHT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family. XerD subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000045296
KOiK04763
OMAiTRQAFWY
OrthoDBiPOG091H00PN

Family and domain databases

Gene3Di1.10.150.130, 1 hit
1.10.443.10, 1 hit
HAMAPiMF_01808 Recomb_XerC_XerD, 1 hit
MF_01807 Recomb_XerD, 1 hit
InterProiView protein in InterPro
IPR011010 DNA_brk_join_enz
IPR013762 Integrase-like_cat_sf
IPR002104 Integrase_catalytic
IPR010998 Integrase_recombinase_N
IPR004107 Integrase_SAM-like_N
IPR011932 Recomb_XerD
IPR023009 Tyrosine_recombinase_XerC/XerD
PfamiView protein in Pfam
PF02899 Phage_int_SAM_1, 1 hit
PF00589 Phage_integrase, 1 hit
SUPFAMiSSF56349 SSF56349, 1 hit

Sequencei

Sequence statusi: Complete.

Q1RHT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEFISQFLEM LLAERALSKN SILSYKRDLL DFHNYLAKQK LSELNITTDN
60 70 80 90 100
IRNWVEYLAE NSLQARSINR KISTIKSYYE FLISENHTNL NPLLNIDLPK
110 120 130 140 150
YQNKLPEILS IDDIKSLLEY CSQDISPEGA RLNAMIHLLY ASGLRVSELV
160 170 180 190 200
SLKLSDILSN KVSREVKKIF SVLGKGNKER IIVINEPAIN SLVKYLVVRD
210 220 230 240 250
NFVNKTKPKN LIYLFPSSAA AGYMTRQNFA ILLKSAALYA GLNPEHISPH
260 270 280 290 300
VLRHSFASHL LEGGADLRVI QELLGHADIS TTQIYTHLQT NHLKKALLHH

PLSKN
Length:305
Mass (Da):34,689
Last modified:May 16, 2006 - v1
Checksum:iB98383395AFBC544
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA Translation: ABE05083.1
RefSeqiWP_011477663.1, NC_007940.1

Genome annotation databases

EnsemblBacteriaiABE05083; ABE05083; RBE_1002
KEGGirbe:RBE_1002

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000087 Genomic DNA Translation: ABE05083.1
RefSeqiWP_011477663.1, NC_007940.1

3D structure databases

ProteinModelPortaliQ1RHT1
SMRiQ1RHT1
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABE05083; ABE05083; RBE_1002
KEGGirbe:RBE_1002

Phylogenomic databases

HOGENOMiHOG000045296
KOiK04763
OMAiTRQAFWY
OrthoDBiPOG091H00PN

Enzyme and pathway databases

BioCyciRBEL336407:G1G4P-1445-MONOMER

Family and domain databases

Gene3Di1.10.150.130, 1 hit
1.10.443.10, 1 hit
HAMAPiMF_01808 Recomb_XerC_XerD, 1 hit
MF_01807 Recomb_XerD, 1 hit
InterProiView protein in InterPro
IPR011010 DNA_brk_join_enz
IPR013762 Integrase-like_cat_sf
IPR002104 Integrase_catalytic
IPR010998 Integrase_recombinase_N
IPR004107 Integrase_SAM-like_N
IPR011932 Recomb_XerD
IPR023009 Tyrosine_recombinase_XerC/XerD
PfamiView protein in Pfam
PF02899 Phage_int_SAM_1, 1 hit
PF00589 Phage_integrase, 1 hit
SUPFAMiSSF56349 SSF56349, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiXERD_RICBR
AccessioniPrimary (citable) accession number: Q1RHT1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: May 16, 2006
Last modified: October 10, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Rickettsia bellii strain RML369-C
    Rickettsia bellii (strain RML369-C): entries and gene names
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Main funding by: National Institutes of Health

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