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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Psychrobacter cryohalolentis (strain K5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. Fructose-1,6-bisphosphate aldolase (Pcryo_0683)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei365Proton donorUniRule annotation1
Active sitei396UniRule annotation1
Active sitei522UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Pcryo_0118
OrganismiPsychrobacter cryohalolentis (strain K5)
Taxonomic identifieri335284 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
Proteomesi
  • UP000002425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002526331 – 555Glucose-6-phosphate isomeraseAdd BLAST555

Proteomic databases

PRIDEiQ1QEK1

Interactioni

Protein-protein interaction databases

STRINGi335284.Pcryo_0118

Structurei

3D structure databases

ProteinModelPortaliQ1QEK1
SMRiQ1QEK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiSFIIPDD
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q1QEK1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNDTKDNKVY SSARHSKYWQ KLKAAAESKW SLAALFAQDN TRTQRFSAQS
60 70 80 90 100
GALYMDYSKQ CLDDTVLESL LNLANSCELS ARIQALLQGA MVNTSEERAA
110 120 130 140 150
LHTALRLPTT ANLQLDNQDV VADVHQSLGQ VERLSERVRS GTWRGFSGKA
160 170 180 190 200
ITDVVNIGVG GSDLGPLMAT TALDEWADTC VEVHFVSNMD GTQLDNLLKH
210 220 230 240 250
LNPETTLFII SSKSFGTIDT LSNAKTALSW LLATAKLRAG TEDSVLRRHF
260 270 280 290 300
IGISANSEKM SAWGIHPEHQ LQLWEWVGGR FSLWSAIGLA IAIRIGMSGF
310 320 330 340 350
KELLAGAHSM DEHFAQADFA ENLPVLLGLI AVWNSTFLQV NAHTVLPYDG
360 370 380 390 400
RLSYLPSYLT QLEMESNGKS VTQHGDRIDY DTCPILWGEI GSNAQHAFYQ
410 420 430 440 450
LLHQGTQQVS CDFIACVRRY SDKAKNTPLQ QQHELSLANC LAQSRVLAFG
460 470 480 490 500
NAAIAETDSQ IACDADKYKY YRGNQPSTTL LIDELTPHSL GALIALYEHK
510 520 530 540 550
VYVMASIWDI NPFDQWGVEM GKQMAESVHD AMQQEGNAPF DTSTNQLLKH

IKQLS
Length:555
Mass (Da):61,432
Last modified:May 16, 2006 - v1
Checksum:iFA9F9B7C47406D40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000323 Genomic DNA Translation: ABE73902.1
RefSeqiWP_011512493.1, NC_007969.1

Genome annotation databases

EnsemblBacteriaiABE73902; ABE73902; Pcryo_0118
KEGGipcr:Pcryo_0118

Similar proteinsi

Entry informationi

Entry nameiG6PI_PSYCK
AccessioniPrimary (citable) accession number: Q1QEK1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: May 16, 2006
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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