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Entry version 97 (11 Dec 2019)
Sequence version 1 (16 May 2006)
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Protein

AP2-like ethylene-responsive transcription factor AIL1

Gene

AIL1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi223 – 289AP2/ERF 1PROSITE-ProRule annotationAdd BLAST67
DNA bindingi325 – 383AP2/ERF 2PROSITE-ProRule annotationAdd BLAST59

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding
Biological processEthylene signaling pathway, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
AP2-like ethylene-responsive transcription factor AIL1
Alternative name(s):
Protein AINTEGUMENTA-LIKE 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AIL1
Ordered Locus Names:At1g72570
ORF Names:F28P22.24
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT1G72570

The Arabidopsis Information Resource

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TAIRi
locus:2030265 AT1G72570

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002903621 – 415AP2-like ethylene-responsive transcription factor AIL1Add BLAST415

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q1PFE1

PRoteomics IDEntifications database

More...
PRIDEi
Q1PFE1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in roots, seedlings, inflorescence, and siliques. Also detected at low levels in leaves.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q1PFE1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q1PFE1 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
28808, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q1PFE1, 12 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT1G72570.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q1PFE1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410II4V Eukaryota
ENOG410YEPX LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000239258

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q1PFE1

KEGG Orthology (KO)

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KOi
K09285

Identification of Orthologs from Complete Genome Data

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OMAi
SHQTEYP

Database of Orthologous Groups

More...
OrthoDBi
455685at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q1PFE1

Family and domain databases

Conserved Domains Database

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CDDi
cd00018 AP2, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.730.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001471 AP2/ERF_dom
IPR036955 AP2/ERF_dom_sf
IPR016177 DNA-bd_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00847 AP2, 2 hits

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00367 ETHRSPELEMNT

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00380 AP2, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54171 SSF54171, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51032 AP2_ERF, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q1PFE1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKWLGFSLT PPLRICNSEE EELRHDGSDV WRYDINFDHH HHDEDVPKVE
60 70 80 90 100
DLLSNSHQTE YPINHNQTNV NCTTVVNRLN PPGYLLHDQT VVTPHYPNLD
110 120 130 140 150
PNLSNDYGGF ERVGSVSVFK SWLEQGTPAF PLSSHYVTEE AGTSNNISHF
160 170 180 190 200
SNEETGYNTN GSMLSLALSH GACSDLINES NVSARVEEPV KVDEKRKRLV
210 220 230 240 250
VKPQVKESVP RKSVDSYGQR TSQYRGVTRH RWTGRYEAHL WDNSCKKEGQ
260 270 280 290 300
TRRGRQVYLG GYDEEEKAAR AYDLAALKYW GPTTHLNFPL SNYEKEIEEL
310 320 330 340 350
NNMNRQEFVA MLRRNSSGFS RGASVYRGVT RHHQHGRWQA RIGRVAGNKD
360 370 380 390 400
LYLGTFSTQE EAAEAYDIAA IKFRGLNAVT NFDINRYDVK RICSSSTIVD
410
SDQAKHSPTS SGAGH
Length:415
Mass (Da):47,133
Last modified:May 16, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i669EE2618C868DC7
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG51860 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence ABK28464 differs from that shown. Reason: Erroneous termination. Extended C-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti96Y → F in AAT12507 (Ref. 1) Curated1
Sequence conflicti116V → F in AAT12507 (Ref. 1) Curated1
Sequence conflicti119 – 120FK → SN in AAT12507 (Ref. 1) Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY603417 mRNA Translation: AAT12507.1
AC010926 Genomic DNA Translation: AAG51860.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE35343.1
DQ446422 mRNA Translation: ABE65765.1
DQ652930 mRNA Translation: ABK28464.1 Sequence problems.

Protein sequence database of the Protein Information Resource

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PIRi
B96750

NCBI Reference Sequences

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RefSeqi
NP_177401.2, NM_105916.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G72570.1; AT1G72570.1; AT1G72570

Database of genes from NCBI RefSeq genomes

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GeneIDi
843589

Gramene; a comparative resource for plants

More...
Gramenei
AT1G72570.1; AT1G72570.1; AT1G72570

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G72570

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY603417 mRNA Translation: AAT12507.1
AC010926 Genomic DNA Translation: AAG51860.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE35343.1
DQ446422 mRNA Translation: ABE65765.1
DQ652930 mRNA Translation: ABK28464.1 Sequence problems.
PIRiB96750
RefSeqiNP_177401.2, NM_105916.2

3D structure databases

SMRiQ1PFE1
ModBaseiSearch...

Protein-protein interaction databases

BioGridi28808, 12 interactors
IntActiQ1PFE1, 12 interactors
STRINGi3702.AT1G72570.1

Proteomic databases

PaxDbiQ1PFE1
PRIDEiQ1PFE1

Genome annotation databases

EnsemblPlantsiAT1G72570.1; AT1G72570.1; AT1G72570
GeneIDi843589
GrameneiAT1G72570.1; AT1G72570.1; AT1G72570
KEGGiath:AT1G72570

Organism-specific databases

AraportiAT1G72570
TAIRilocus:2030265 AT1G72570

Phylogenomic databases

eggNOGiENOG410II4V Eukaryota
ENOG410YEPX LUCA
HOGENOMiHOG000239258
InParanoidiQ1PFE1
KOiK09285
OMAiSHQTEYP
OrthoDBi455685at2759
PhylomeDBiQ1PFE1

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q1PFE1

Gene expression databases

ExpressionAtlasiQ1PFE1 baseline and differential
GenevisibleiQ1PFE1 AT

Family and domain databases

CDDicd00018 AP2, 2 hits
Gene3Di3.30.730.10, 2 hits
InterProiView protein in InterPro
IPR001471 AP2/ERF_dom
IPR036955 AP2/ERF_dom_sf
IPR016177 DNA-bd_dom_sf
PfamiView protein in Pfam
PF00847 AP2, 2 hits
PRINTSiPR00367 ETHRSPELEMNT
SMARTiView protein in SMART
SM00380 AP2, 2 hits
SUPFAMiSSF54171 SSF54171, 2 hits
PROSITEiView protein in PROSITE
PS51032 AP2_ERF, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAIL1_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1PFE1
Secondary accession number(s): A0MEG0, Q6J335, Q9CAH3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: May 16, 2006
Last modified: December 11, 2019
This is version 97 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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