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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Lawsonia intracellularis (strain PHE/MN1-00)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciLINT363253:G1GJC-820-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:LI0738
OrganismiLawsonia intracellularis (strain PHE/MN1-00)
Taxonomic identifieri363253 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeLawsonia
Proteomesi
  • UP000002430 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002640531 – 201Peptidyl-tRNA hydrolaseAdd BLAST201

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi363253.LI0738

Structurei

3D structure databases

ProteinModelPortaliQ1MQD5
SMRiQ1MQD5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1MQD5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSIKGIIAGL GNPGGQYEKT RHNIGFMVIN KLITITSASK LSGKKFYCEL
60 70 80 90 100
WKTTTIIDNY LLAKPQTYMN LSGEAIHPLV EWYNITKDNL LVIHDELDLP
110 120 130 140 150
IGKMKLQQGG GTAGHNGLKS IIHNLGTKDF YRLRIGIGRS PLPSENTVNW
160 170 180 190 200
VLGHLSMKEL TTLNNLFPTI FDALSFFIKD EKETAIRMIN SFTLSETVNL

S
Length:201
Mass (Da):22,454
Last modified:May 30, 2006 - v1
Checksum:iB645EB407F85A4CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180252 Genomic DNA Translation: CAJ54792.1
RefSeqiWP_011526821.1, NC_008011.1

Genome annotation databases

KEGGilip:LI0738

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180252 Genomic DNA Translation: CAJ54792.1
RefSeqiWP_011526821.1, NC_008011.1

3D structure databases

ProteinModelPortaliQ1MQD5
SMRiQ1MQD5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi363253.LI0738

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGilip:LI0738

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Enzyme and pathway databases

BioCyciLINT363253:G1GJC-820-MONOMER

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPTH_LAWIP
AccessioniPrimary (citable) accession number: Q1MQD5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 30, 2006
Last modified: October 10, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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