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Protein

Glutaminase

Gene

glsA

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei64SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1
Binding sitei160SubstrateUniRule annotation1
Binding sitei167SubstrateUniRule annotation1
Binding sitei191SubstrateUniRule annotation1
Binding sitei243SubstrateUniRule annotation1
Binding sitei261Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:RL2623
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000006575 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000483481 – 309GlutaminaseAdd BLAST309

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi216596.RL2623

Structurei

3D structure databases

ProteinModelPortaliQ1MG12
SMRiQ1MG12
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
KOiK01425
OMAiEPSGNPF
OrthoDBiPOG091H02PU

Family and domain databases

HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR015868 Glutaminase
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF04960 Glutaminase, 1 hit
SUPFAMiSSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit

Sequencei

Sequence statusi: Complete.

Q1MG12-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADLQATLDS IYADIQPRIG EGKVADYIPE LAKVDPQQFG MAIVTVDGKV
60 70 80 90 100
YRVGNADTAF SIQSISKVFM LTLALGKVGE GLWKRVGREP SGSAFNSIVQ
110 120 130 140 150
LEHESGIPRN PFINAGAIAV SDVVMAGHAP REAIGELLRF VRYLADDESI
160 170 180 190 200
TIDDKVARSE TQTGYRNFAL ANFMRAYRNL DHPVDHVLGV YFHQCALSMS
210 220 230 240 250
CEQLARAGLF LAARGSNPTT GHSVVSPKRA RRINALMLTC GHYDGSGDFA
260 270 280 290 300
YHVGLPGKSG VGGGIFAVAP GIASIAVWSP GLNKVGNSQL GAAALEMLAA

RTGWSVFGD
Length:309
Mass (Da):32,925
Last modified:May 30, 2006 - v1
Checksum:iF8A496BEAD38E959
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA Translation: CAK08111.1
RefSeqiWP_011652167.1, NC_008380.1

Genome annotation databases

EnsemblBacteriaiCAK08111; CAK08111; RL2623
KEGGirle:RL2623

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA Translation: CAK08111.1
RefSeqiWP_011652167.1, NC_008380.1

3D structure databases

ProteinModelPortaliQ1MG12
SMRiQ1MG12
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216596.RL2623

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK08111; CAK08111; RL2623
KEGGirle:RL2623

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
KOiK01425
OMAiEPSGNPF
OrthoDBiPOG091H02PU

Family and domain databases

HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR015868 Glutaminase
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF04960 Glutaminase, 1 hit
SUPFAMiSSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_RHIL3
AccessioniPrimary (citable) accession number: Q1MG12
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 30, 2006
Last modified: October 10, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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