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Protein

Adenine deaminase 2

Gene

ade2

Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminase 2UniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
Adenase 2UniRule annotation
Short name:
Adenine aminase 2UniRule annotation
Gene namesi
Name:ade2UniRule annotation
Ordered Locus Names:RL3883
OrganismiRhizobium leguminosarum bv. viciae (strain 3841)
Taxonomic identifieri216596 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000006575 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002923951 – 595Adenine deaminase 2Add BLAST595

Interactioni

Protein-protein interaction databases

STRINGi216596.RL3883

Structurei

3D structure databases

ProteinModelPortaliQ1MCF8
SMRiQ1MCF8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN Bacteria
COG1001 LUCA
HOGENOMiHOG000276949
KOiK01486
OMAiIEGHFPG
OrthoDBiPOG091H00I8

Family and domain databases

Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PANTHERiPTHR11113:SF2 PTHR11113:SF2, 1 hit
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit

Sequencei

Sequence statusi: Complete.

Q1MCF8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNATARQEPA DLNDPALRAR AVTAARGDAP FDMLITGGRL LDTVTGLIRQ
60 70 80 90 100
ADIGLVGALI SSVHAPASRT DAVEIIDAAG SILTPGLIDT HMHIESSMVT
110 120 130 140 150
PAEYASAVLP RGVTTIVWDP HEFGNVHGLD GVRWAIEAAR SLPLRMILLA
160 170 180 190 200
PSCVPSAPGL ELAGADFDAS MITEMLHSSA VGGVAEVMNM RGVIDGDPRM
210 220 230 240 250
TDIVNAGLAA GKLVCGHARG LEGADLNAFM ASGITSDHEL TSGADLLAKL
260 270 280 290 300
SAGLTIELRG SHDHLLQEFV EVLSGLGHLP PTVTLCTDDV FPDELQEGGG
310 320 330 340 350
LDDVVRRLVR YGMKPEWAIR AATFNAAQRL KRSDLGLVAT GRRADIVLFE
360 370 380 390 400
DLTEFRARLV ISGGRIVARN GSMQVAVQQI DTAPLVNSVK LPPLTENDFR
410 420 430 440 450
IPAKGERVRV ATIDRPRFTQ WGEAETEVRD GFIVPPAGSA MISVAHRHGK
460 470 480 490 500
TDGIPRIGFL TGWGEWRGAF CTTVSHDSHN LTVFGGNAGD MALAANAVIS
510 520 530 540 550
AGGGMAVAKD GRIEAMLPLP LSGLVTDASL KDTALAFAGI RKAMEKIVTW
560 570 580 590
KPPYLVFKAC FGATLACNVG PHQTDQGIAD VVTGKVLENP VLAVW
Length:595
Mass (Da):62,817
Last modified:May 30, 2006 - v1
Checksum:i54D0D1C8F6DC3D5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA Translation: CAK09373.1
RefSeqiWP_011653318.1, NC_008380.1

Genome annotation databases

EnsemblBacteriaiCAK09373; CAK09373; RL3883
KEGGirle:RL3883

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM236080 Genomic DNA Translation: CAK09373.1
RefSeqiWP_011653318.1, NC_008380.1

3D structure databases

ProteinModelPortaliQ1MCF8
SMRiQ1MCF8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216596.RL3883

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK09373; CAK09373; RL3883
KEGGirle:RL3883

Phylogenomic databases

eggNOGiENOG4105CPN Bacteria
COG1001 LUCA
HOGENOMiHOG000276949
KOiK01486
OMAiIEGHFPG
OrthoDBiPOG091H00I8

Family and domain databases

Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PANTHERiPTHR11113:SF2 PTHR11113:SF2, 1 hit
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiADEC2_RHIL3
AccessioniPrimary (citable) accession number: Q1MCF8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: May 30, 2006
Last modified: October 10, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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