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Entry version 116 (02 Dec 2020)
Sequence version 2 (10 Jul 2007)
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Protein
Submitted name:

PATJ crumbs cell polarity complex component

Gene

patj

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
PATJ crumbs cell polarity complex componentImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:patjImported
Synonyms:inadlImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-030616-129, patj

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000024964, Expressed in mature ovarian follicle and 29 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000116882

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 69L27InterPro annotationAdd BLAST61
Domaini131 – 218PDZInterPro annotationAdd BLAST88
Domaini240 – 320PDZInterPro annotationAdd BLAST81
Domaini364 – 450PDZInterPro annotationAdd BLAST87
Domaini546 – 632PDZInterPro annotationAdd BLAST87
Domaini733 – 808PDZInterPro annotationAdd BLAST76
Domaini1055 – 1147PDZInterPro annotationAdd BLAST93
Domaini1225 – 1308PDZInterPro annotationAdd BLAST84
Domaini1467 – 1550PDZInterPro annotationAdd BLAST84
Domaini1563 – 1645PDZInterPro annotationAdd BLAST83
Domaini1641 – 1712PDZInterPro annotationAdd BLAST72
Domaini1748 – 1831PDZInterPro annotationAdd BLAST84

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni323 – 352DisorderedSequence analysisAdd BLAST30
Regioni679 – 725DisorderedSequence analysisAdd BLAST47
Regioni901 – 953DisorderedSequence analysisAdd BLAST53
Regioni988 – 1050DisorderedSequence analysisAdd BLAST63
Regioni1152 – 1210DisorderedSequence analysisAdd BLAST59
Regioni1322 – 1443DisorderedSequence analysisAdd BLAST122
Regioni1723 – 1747DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi323 – 350Pro-richSequence analysisAdd BLAST28
Compositional biasi679 – 704PolyampholyteSequence analysisAdd BLAST26
Compositional biasi705 – 724AcidicSequence analysisAdd BLAST20
Compositional biasi915 – 952PolarSequence analysisAdd BLAST38
Compositional biasi1025 – 1044PolyampholyteSequence analysisAdd BLAST20
Compositional biasi1351 – 1380PolarSequence analysisAdd BLAST30
Compositional biasi1381 – 1396PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1401 – 1443PolarSequence analysisAdd BLAST43

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3528, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155136

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002378_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q1LXN3

Identification of Orthologs from Complete Genome Data

More...
OMAi
ESHYILH

Database of Orthologous Groups

More...
OrthoDBi
1419918at2759

TreeFam database of animal gene trees

More...
TreeFami
TF330709

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.42.10, 11 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015132, L27_2
IPR004172, L27_dom
IPR036892, L27_dom_sf
IPR001478, PDZ
IPR036034, PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09045, L27_2, 1 hit
PF00595, PDZ, 10 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228, PDZ, 11 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101288, SSF101288, 1 hit
SSF50156, SSF50156, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51022, L27, 1 hit
PS50106, PDZ, 11 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q1LXN3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYENVPTVSA SERQQVLQAL ERLQSKLVQR EEWTHSDRLG TLKEALQSPL
60 70 80 90 100
FSHILTLQHS VKQLKDQLNS LPPDTCSEFS FSRKGQLIVS ASRPSSSLGS
110 120 130 140 150
VLSNGTALTN ASSEQLQRWI QAAAKGRKTE LISLQKPLSG GLGFSVVGLR
160 170 180 190 200
PEGVGGHGVF VRQVQPGSVA DRDGRLLEND QILAINGIPL DQSVTQQQAI
210 220 230 240 250
ALLQQQKDRV ELVVARDTAL KPRLSASAPI TTDQWGHVEE IELVNDGSGL
260 270 280 290 300
GFGIVGGKTT GMVVRTVVPG SVADKDGRLR TGDHILRIGD TMTRGLASDQ
310 320 330 340 350
VVQVLQACGA HVRMLIAREP LGAKQPAPPP APAMGPVSSL PPPPPVPARR
360 370 380 390 400
ASRTPNLEGF EIHEVALKKE GQSLGISIIG HNALTSEDAV GVYVKNVIPG
410 420 430 440 450
SIAEQTGKIQ IHDRIISLDG VNLQGYNNQE VLEVMKQSGD VVHLTLVRKI
460 470 480 490 500
ISPKRTTMEK SLDKVQRESS RVSLKRSSEM KARADQRGSV VESIDPALSG
510 520 530 540 550
IKQQLQANMQ EPASLTEMEL RAKWEQALGP HYDVMIVQLD PVIEDDIELQ
560 570 580 590 600
KYSKLLPIHT MRLGVELDSF DGHHYISTVA PEGPVAKHGL LRPEDELLEV
610 620 630 640 650
NGVQLYGKSR RESVAFLREV PTPFTLVCCR RLAKEDNEYH PESEDWHSSS
660 670 680 690 700
LQEQIEHNLS MLARDTSLRD SIREEFQARQ ASAVEREVDD EGEPLEPISP
710 720 730 740 750
EKEQMDQEND DDDEEEEEED EGELALWSPN VQVLELEKAE RGLGFSILDY
760 770 780 790 800
QDPMDVARSV IVIRSLVPGG VADNHGGIFP GDQLVFVNDT HLETCSLAQA
810 820 830 840 850
VEVLKSAPPG KVYLGIRKPL AAEDRGSGQQ SLWPVESVDE QPTAKQAVSH
860 870 880 890 900
TLPPMPEDFV NGSILSDDLD EEPELILDAE PRYASPLTTV DLQPDVEKEM
910 920 930 940 950
AVDEEEEDVD VNVMEDQQSS KVNDTSLPSY LSEKSRSWEE PATSSRYHLN
960 970 980 990 1000
TEPDLQEQVD DDLSMNLEKI QLQPLKIPLG HFTSWVETAD SDSDSRNEGS
1010 1020 1030 1040 1050
ELTLTDTDNE SAQRTSSRNK KRRNQAGPTR GDLPEREEGE GEETPVFSHW
1060 1070 1080 1090 1100
GPPRRVEVWA EPEESLGISI VGGRTVIKRL KNGEELKGIF IKQVLADSPA
1110 1120 1130 1140 1150
GRTGALKTGD KILQVSGVDL QNASHEEAVQ TIKAAPSPVV FIVQSLSSTP
1160 1170 1180 1190 1200
RPVSVTASSI KQHKAKRKAA QKAGQGAAPP PMRLPPPYRP PSQVQEEEHE
1210 1220 1230 1240 1250
QEEEDEQDTE VIRQRYADLP GELLIVELEK DRNGLGLSLA GNRDRSCMSI
1260 1270 1280 1290 1300
FVVGITTGGP ASRDGRIKVG DELLEINSQV LYGRSHQNAS AIIKSAASKV
1310 1320 1330 1340 1350
KLVLVRNEDA INQMAVTPFP SQPALFSSSE THENPPAVPA EKPQLPESLP
1360 1370 1380 1390 1400
LSRSPPENTL NKDQACVTAT ASSDPTHKSL TDGESAVKKL KPAEKLLESP
1410 1420 1430 1440 1450
SEQSAKPQVE QIPSLPKLQR SSTKPSAGSL EVTSSASSVP VSGTSPDFEY
1460 1470 1480 1490 1500
CSKDPATCPI VPGQETVIEI SKGRSGLGLS IVGGKDTQLD AIVIHEVYEE
1510 1520 1530 1540 1550
GAAARDGRLW AGDQILEVNG VDLRSVAHED AIAALRQTPP KVRLTVLRDE
1560 1570 1580 1590 1600
AQYRDEENLD VFPVELQKKT GRGLGLSIVG KRNGKGVFIS DVVKGGAADL
1610 1620 1630 1640 1650
DGRLMQGDQI LSVDGEDMRQ ASQETVAAIL KGPTDALGIS IAGGKGSPLG
1660 1670 1680 1690 1700
DIPIFIAMIQ ANGVAAKTHR LKVGDRIVSI NSQSLDGLTH ADVVNMLKNA
1710 1720 1730 1740 1750
YGAIILQVVA DTNISAIASQ VESLSSSSAP STNPEVRLVE PETPKPKSIT
1760 1770 1780 1790 1800
LEKGSEGLGF SIVGGFGSPH GDLPIYVKTV FGKGAAAVDG RLKRGDQLLS
1810 1820 1830
VNGESLEGVT HEQAVAILKK QRGSVTLSVL T
Length:1,831
Mass (Da):198,291
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D48FC10407DEF2E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8QUA7A0A2R8QUA7_DANRE
PATJ crumbs cell polarity complex c...
patj
1,914Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8DZE1A8DZE1_DANRE
PATJ crumbs cell polarity complex c...
patj inadl
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL929239 Genomic DNA No translation available.
BX322568 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001120657.1, NM_001127185.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000036467; ENSDARP00000035306; ENSDARG00000024964
ENSDART00000132829; ENSDARP00000116882; ENSDARG00000024964

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
368723

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:368723

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929239 Genomic DNA No translation available.
BX322568 Genomic DNA No translation available.
RefSeqiNP_001120657.1, NM_001127185.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000116882

Genome annotation databases

EnsembliENSDART00000036467; ENSDARP00000035306; ENSDARG00000024964
ENSDART00000132829; ENSDARP00000116882; ENSDARG00000024964
GeneIDi368723
KEGGidre:368723

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10207
ZFINiZDB-GENE-030616-129, patj

Phylogenomic databases

eggNOGiKOG3528, Eukaryota
GeneTreeiENSGT00940000155136
HOGENOMiCLU_002378_0_0_1
InParanoidiQ1LXN3
OMAiESHYILH
OrthoDBi1419918at2759
TreeFamiTF330709

Gene expression databases

BgeeiENSDARG00000024964, Expressed in mature ovarian follicle and 29 other tissues

Family and domain databases

Gene3Di2.30.42.10, 11 hits
InterProiView protein in InterPro
IPR015132, L27_2
IPR004172, L27_dom
IPR036892, L27_dom_sf
IPR001478, PDZ
IPR036034, PDZ_sf
PfamiView protein in Pfam
PF09045, L27_2, 1 hit
PF00595, PDZ, 10 hits
SMARTiView protein in SMART
SM00228, PDZ, 11 hits
SUPFAMiSSF101288, SSF101288, 1 hit
SSF50156, SSF50156, 11 hits
PROSITEiView protein in PROSITE
PS51022, L27, 1 hit
PS50106, PDZ, 11 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ1LXN3_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1LXN3
Secondary accession number(s): F1QUF9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: July 10, 2007
Last modified: December 2, 2020
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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