Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

Gene

ndufs6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.UniRule annotation

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotation, Transport

Enzyme and pathway databases

ReactomeiR-DRE-611105 Respiratory electron transport
R-DRE-6799198 Complex I biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrialUniRule annotation
Gene namesi
Name:ndufs6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-040912-86 ndufs6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ1LWG2

Expressioni

Gene expression databases

BgeeiENSDARG00000056583 Expressed in 29 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiQ1LWG2 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000073559

Structurei

3D structure databases

ProteinModelPortaliQ1LWG2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 123zf-CHCCInterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the complex I NDUFS6 subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3456 Eukaryota
ENOG4111W6X LUCA
GeneTreeiENSGT00390000015775
HOGENOMiHOG000161276
HOVERGENiHBG006549
InParanoidiQ1LWG2
OMAiGNHICGY
OrthoDBiEOG091G12A5
TreeFamiTF315128

Family and domain databases

InterProiView protein in InterPro
IPR016668 NDUFS6
IPR019401 Znf_CHCC
PfamiView protein in Pfam
PF10276 zf-CHCC, 1 hit
PIRSFiPIRSF016564 CI-13KD-A, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q1LWG2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAILPRILS FGKNTKVLLN CLRLSAVPVQ QYSVPVSNHG EIITHTGQVY
60 70 80 90 100
DENDVRRARF VGRHKEVNEN FAINLVAEEP VSHVESRVVS CDGGGGALGH
110 120
PKVYINLDKD TRVGTCGYCG LQFKQTHHH
Length:129
Mass (Da):14,232
Last modified:May 30, 2006 - v1
Checksum:iB73BEB95A6B7CF91
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
I3ISK7I3ISK7_DANRE
NADH:ubiquinone oxidoreductase subu...
ndufs6
110Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571830 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000079104; ENSDARP00000073559; ENSDARG00000056583

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571830 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ1LWG2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000073559

Proteomic databases

PaxDbiQ1LWG2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000079104; ENSDARP00000073559; ENSDARG00000056583

Organism-specific databases

ZFINiZDB-GENE-040912-86 ndufs6

Phylogenomic databases

eggNOGiKOG3456 Eukaryota
ENOG4111W6X LUCA
GeneTreeiENSGT00390000015775
HOGENOMiHOG000161276
HOVERGENiHBG006549
InParanoidiQ1LWG2
OMAiGNHICGY
OrthoDBiEOG091G12A5
TreeFamiTF315128

Enzyme and pathway databases

ReactomeiR-DRE-611105 Respiratory electron transport
R-DRE-6799198 Complex I biogenesis

Gene expression databases

BgeeiENSDARG00000056583 Expressed in 29 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiQ1LWG2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016668 NDUFS6
IPR019401 Znf_CHCC
PfamiView protein in Pfam
PF10276 zf-CHCC, 1 hit
PIRSFiPIRSF016564 CI-13KD-A, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ1LWG2_DANRE
AccessioniPrimary (citable) accession number: Q1LWG2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: September 12, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again