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Entry version 98 (07 Apr 2021)
Sequence version 1 (30 May 2006)
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Protein
Submitted name:

Spalt-like transcription factor 3b

Gene

sall3b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Spalt-like transcription factor 3bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sall3bImported
Synonyms:sallbImported, si:dkey-195c14.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-030131-9140, sall3b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q1LVB0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000057586, Expressed in material anatomical entity and 15 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000074744

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini439 – 466C2H2-typeInterPro annotationAdd BLAST28
Domaini467 – 494C2H2-typeInterPro annotationAdd BLAST28
Domaini711 – 738C2H2-typeInterPro annotationAdd BLAST28
Domaini739 – 766C2H2-typeInterPro annotationAdd BLAST28
Domaini771 – 798C2H2-typeInterPro annotationAdd BLAST28
Domaini1072 – 1099C2H2-typeInterPro annotationAdd BLAST28
Domaini1100 – 1127C2H2-typeInterPro annotationAdd BLAST28

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 51DisorderedSequence analysisAdd BLAST51
Regioni558 – 607DisorderedSequence analysisAdd BLAST50
Regioni838 – 868DisorderedSequence analysisAdd BLAST31
Regioni1208 – 1234DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi8 – 22PolyampholyteSequence analysisAdd BLAST15
Compositional biasi29 – 51PolyampholyteSequence analysisAdd BLAST23
Compositional biasi558 – 572PolarSequence analysisAdd BLAST15
Compositional biasi583 – 607PolarSequence analysisAdd BLAST25
Compositional biasi842 – 868PolarSequence analysisAdd BLAST27

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1074, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159356

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005740_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
EPNCLEM

Database of Orthologous Groups

More...
OrthoDBi
244207at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q1LVB0

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 7 hits
PS50157, ZINC_FINGER_C2H2_2, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q1LVB0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRRKQAKPQ HLRSDEEGTQ SDKSPDNALL LRGGDEEDSG TESRSGGEET
60 70 80 90 100
HVCERCCAEF FKWSEMLEHQ QKCTEDPPVL IVKEKEEKVI SRGSPTESLF
110 120 130 140 150
SAQSDSAEME ASEINSELAE KVDEMPEETH IIDLDEQMDI SLPEHKTSNL
160 170 180 190 200
SPLPLDDENA TSPPAPPITN HYDMPSTNVT LEILHSTRVA VAQFSQSIHC
210 220 230 240 250
AGSAGKLNSA AIPMILEQLM ALQQQQVQQL QLIEQIRSQV AVMNRQPTQA
260 270 280 290 300
ALNPASKSLP SDSNTYNFQG IAPPPVLPLS GVMPSTVNGQ ASVSQASMLA
310 320 330 340 350
RPSLLSSQPS TGQIGSRALD SATSSLTSSS PHLFSYSGAS PLLPTCSGSL
360 370 380 390 400
SNVSNTQSVS TPSPLSACQS SLLSPSANLP LLPQSPPNGV IFPNPLASIA
410 420 430 440 450
ATASALDPLA AMMKHRKGKL PSVSIFDSKP SSEDPFFKHK CRFCAKVFGS
460 470 480 490 500
DSALQIHLRS HTGERPFKCN ICGNRFSTKG NLKVHFQRHK EKYPHVQMNP
510 520 530 540 550
YPVPEYLDNI PTSSGIPYGM SFPPEKAGPT WLDSKPVLPT VPSSVGLQLP
560 570 580 590 600
PTVPIIESLS DSFTSTPSER SPHRPSPARG ELAPSSPNPT GTETDVSTIA
610 620 630 640 650
ASPKSNREAE ITQSFNTEEV HLPSNSLIRN GSNSNILLSQ SMLTETPVKG
660 670 680 690 700
NVPESTDVPS AIIKPSSPPL ISDQFRSKFP FGGLQDSMQT SETSKLQQLV
710 720 730 740 750
ENIDKKMMEP NQCVICHRVL SCQSALKMHY RIHTGERPFK CKVCGRAFTT
760 770 780 790 800
KGNLKTHFGV HRAKPPLRIQ HSCPICQKKF TNAVVLQQHI RMHMGGQIPN
810 820 830 840 850
TPLAETIYEK DTDMESFDSM STYDDDCLDD ISFEEEGDVV ENSENTLSSF
860 870 880 890 900
SDSPPPISSL PSSISESQNV GGDLSINLSQ SNGKKMVRCD PMDNDLHAPH
910 920 930 940 950
TSTGEMENHS MGNSLMPHSS SSIHIPTYSN SQPEGQHEHS VSLNLSSKTP
960 970 980 990 1000
EAAAIVKSES TDCPAANAVN GVTLNQTGIQ PIKSSVKKEN PFNVQCFSKE
1010 1020 1030 1040 1050
HENVQRSTEQ DTKNLPTAVK LEMSICSRPY MLKEGPFPAF GLQSPTSRSE
1060 1070 1080 1090 1100
VMIPGVTSLT GPPPPRRTPK QHNCSACGKN FSSASALQIH ERTHTGEKPF
1110 1120 1130 1140 1150
GCSVCGRAFT TKGNLKVHMG THMWNNTPAR RGRRLSVENP IALLGGDALK
1160 1170 1180 1190 1200
FSEAFQKDLA ARAMNVDQNF WSRYAAAITN GLAMRNNEIS VIQSGGVPQL
1210 1220 1230 1240
PAITVATDKA STGNSPPITA MEKTGLERGP GQHFSMMIDD KKDIGIN
Length:1,247
Mass (Da):135,115
Last modified:May 30, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3835930188B2ACCE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX890563 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001038615.1, NM_001045150.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000100181; ENSDARP00000090954; ENSDARG00000057586

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
568041

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:568041

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX890563 Genomic DNA No translation available.
RefSeqiNP_001038615.1, NM_001045150.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000074744

Proteomic databases

PaxDbiQ1LVB0

Genome annotation databases

EnsembliENSDART00000100181; ENSDARP00000090954; ENSDARG00000057586
GeneIDi568041
KEGGidre:568041

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
568041
ZFINiZDB-GENE-030131-9140, sall3b

Phylogenomic databases

eggNOGiKOG1074, Eukaryota
GeneTreeiENSGT00940000159356
HOGENOMiCLU_005740_0_0_1
OMAiEPNCLEM
OrthoDBi244207at2759
PhylomeDBiQ1LVB0

Gene expression databases

BgeeiENSDARG00000057586, Expressed in material anatomical entity and 15 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 8 hits
SUPFAMiSSF57667, SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 7 hits
PS50157, ZINC_FINGER_C2H2_2, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ1LVB0_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1LVB0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 30, 2006
Last sequence update: May 30, 2006
Last modified: April 7, 2021
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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