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Protein

Major facilitator superfamily domain-containing protein 6-A

Gene

mfsd6a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Major facilitator superfamily domain-containing protein 6-A
Alternative name(s):
Macrophage MHC class I receptor 2 homolog A
Gene namesi
Name:mfsd6a
Synonyms:mfsd6, mmr2
ORF Names:si:dkey-188p4.2
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 22

Organism-specific databases

ZFINiZDB-GENE-050208-335 mfsd6a

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei75 – 95HelicalSequence analysisAdd BLAST21
Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Transmembranei134 – 154HelicalSequence analysisAdd BLAST21
Transmembranei297 – 317HelicalSequence analysisAdd BLAST21
Transmembranei340 – 360HelicalSequence analysisAdd BLAST21
Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Transmembranei461 – 481HelicalSequence analysisAdd BLAST21
Transmembranei489 – 509HelicalSequence analysisAdd BLAST21
Transmembranei555 – 575HelicalSequence analysisAdd BLAST21
Transmembranei590 – 610HelicalSequence analysisAdd BLAST21
Transmembranei616 – 636HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003219431 – 793Major facilitator superfamily domain-containing protein 6-AAdd BLAST793

Proteomic databases

PaxDbiQ1LUQ4

Expressioni

Gene expression databases

BgeeiENSDARG00000032318

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000063028

Structurei

3D structure databases

ProteinModelPortaliQ1LUQ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi242 – 281Thr-richAdd BLAST40

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3762 Eukaryota
ENOG410YMHR LUCA
GeneTreeiENSGT00530000063599
HOVERGENiHBG100740
InParanoidiQ1LUQ4
OMAiHEPKEYV
OrthoDBiEOG091G03VH
PhylomeDBiQ1LUQ4
TreeFamiTF314366

Family and domain databases

CDDicd06174 MFS, 2 hits
InterProiView protein in InterPro
IPR024989 MFS_assoc_dom
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF12832 MFS_1_like, 1 hit
SUPFAMiSSF103473 SSF103473, 2 hits

Sequencei

Sequence statusi: Complete.

Q1LUQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADDRVAILT EDEEELKRKH LERFDRLSLE IQSPSQPPEN DVPNDTAPTP
60 70 80 90 100
SPQHELSCCE RLFLRVNRHL LVSKVFYLFF YAAYGSLHPL LALYYKQLGM
110 120 130 140 150
NPTQSGLLVG IRYFIEFCSA PFWGIVADRY RKGKAVLLFS MLCWILFNAG
160 170 180 190 200
IGIVKPPIMA CKEETIPTTT KVPTVHPTPS NETFFPNTSS TSQMRRRRDL
210 220 230 240 250
IGQYPWRTIL SSGQSSGYIS EHRIKRDSNL SFTPAPEELA NTTQTNQTST
260 270 280 290 300
TTQPKPSTSI STSTPSSTNT TSSSTTKSTT TNPNLPPPEY NMDQVNAIFL
310 320 330 340 350
LILLVIIIGE FFSAPAITIV DTVTLHYLGP HRDRYGLQRM WGSLGWGLAM
360 370 380 390 400
LCIGIWIDHT STNLIIGNME CIMKNYKNYH IAFIVFGVLM VIALIVATQF
410 420 430 440 450
KFDVQHHDTN EGQEVGNQQE NVQPRGSPGT RSTDTPTIVQ AEEFHFWDLM
460 470 480 490 500
RLLCGVQYST VLFVAWFMGF GYGFVFTFLY WHLQDLTGTT TLFGICSVLS
510 520 530 540 550
HVSELAAYFT SHKFIELVGH IRVLYIGLAC NTARYLYISY LENAWTVLPM
560 570 580 590 600
EVLQGITHAS VWAACISYLS AAVPPPLRTS AQGILQGLHL GLGRGCGAMV
610 620 630 640 650
GGIFVNYFGV AETFRGIGMA SLVILLIFSL IMYITGQNEK KEDKMLAENI
660 670 680 690 700
PIPSSPVPIA TIDLVQNTAD VAAPARPEPK LPARKTQHQQ EQEDLNKPAW
710 720 730 740 750
VPSGSPWVSV ALLVYQIREM VLLAKARPTV EVQPLQGTDE VRSDSQEDQS
760 770 780 790
PPVFSDAVQN ENTPSGLQDH SGSPTAQLDV PTRDTQPPSQ HIS
Length:793
Mass (Da):88,232
Last modified:May 30, 2006 - v1
Checksum:iBE0E5BDD351F6E1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX927260 Genomic DNA Translation: CAK05334.1
RefSeqiNP_001076525.1, NM_001083056.1
XP_005161736.1, XM_005161679.3
UniGeneiDr.120107

Genome annotation databases

EnsembliENSDART00000063029; ENSDARP00000063028; ENSDARG00000032318
GeneIDi100034426
KEGGidre:100034426

Similar proteinsi

Entry informationi

Entry nameiMFD6A_DANRE
AccessioniPrimary (citable) accession number: Q1LUQ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: May 30, 2006
Last modified: June 20, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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