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Protein

Zinc finger CCCH domain-containing protein 18

Gene

zc3h18

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger CCCH domain-containing protein 18
Gene namesi
Name:zc3h18
ORF Names:si:ch211-218c6.1
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 18

Organism-specific databases

ZFINiZDB-GENE-050419-13 zc3h18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003112451 – 1148Zinc finger CCCH domain-containing protein 18Add BLAST1148

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei666Phosphoserine1 Publication1
Modified residuei1056Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ1LUE5
PRIDEiQ1LUE5

PTM databases

iPTMnetiQ1LUE5

Expressioni

Gene expression databases

BgeeiENSDARG00000062506 Expressed in 29 organ(s), highest expression level in mature ovarian follicle
ExpressionAtlasiQ1LUE5 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000122210

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili543 – 584Sequence analysisAdd BLAST42
Coiled coili1118 – 1146Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi15 – 308Glu-richAdd BLAST294
Compositional biasi340 – 343Poly-Phe4
Compositional biasi379 – 424Pro-richAdd BLAST46
Compositional biasi677 – 924Ser-richAdd BLAST248
Compositional biasi925 – 1102Pro-richAdd BLAST178

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IJ7N Eukaryota
ENOG4111IXQ LUCA
GeneTreeiENSGT00730000111190
HOGENOMiHOG000155765
InParanoidiQ1LUE5
KOiK13092
OrthoDBiEOG091G03UA
PhylomeDBiQ1LUE5
TreeFamiTF327301

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q1LUE5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDTPESPTQS PQSPEEEEKG LSDNELLESP ESPAEADKGV SDSELLNDDE
60 70 80 90 100
NEVPEHGGDS DSEDRDRQPA GREDPEELSD VEDYKLDREE REDIHQQEGA
110 120 130 140 150
LRVQEIAQKA IKSPEEEILE TPRSPDPVSP AAEHERPFTP AEEERGDDDE
160 170 180 190 200
EEEEDETTTK SGLGQAELEE EEDEEEERRR RRRAAMVVSD LKDESSVSRD
210 220 230 240 250
LDEHELDYDE EVPEEPSAAA PEEDEPEKPA VGEDGEDEEE EDEEEEKRRK
260 270 280 290 300
RKERKPILPP DNRDTPLRKS EDSREGGRRD SFRDKKKEED DGEIDEGEID
310 320 330 340 350
DDDLEEGEVK DPMDRKIRPR PICRFFMKGS FVTMYGNVKF FFFKSYLVFL
360 370 380 390 400
TGNCTWGMIC RFIHPGVNDK GNYSLISKPD PFSPNGAPPG GAAGGGPHPL
410 420 430 440 450
MPANPWGAPA VEELPPPPPP LDPPVESAWE RGLRHAKEVL KKATIRKEQE
460 470 480 490 500
PDFEEKRFTV TIGEDDRDFD KENDFFRERG GYRITREIRD AGSDPYGDPY
510 520 530 540 550
YDYEMEAFWR GGQYENFRVQ YTETPLPYYP DRERERDPRE RHRERERERE
560 570 580 590 600
RDHRERERRQ RERERERERE REKDSRRRKD EWDRDRLKRD EKEGRPRERP
610 620 630 640 650
LREPREKKDE KEKTLKPRSP TNMPPRGPME PPTKKDMLSV TKRPDEWNDP
660 670 680 690 700
WCRSKSPRRR PGFMGSPPRG RRRHRPSGSS VSLSNSSRSS SRSSSFTGSG
710 720 730 740 750
SSRSRSRSRS SSMSSYSSHS SQHSSFSGSR SRSGSFSSSP SPSPSAQRNA
760 770 780 790 800
NKNKAEQPPA AAKGPPLKPG ALPPPRRDKG PPKVMPSPSL PEQPGKPPKP
810 820 830 840 850
ITETVKPPNP RPPGRPPGPR EPREPPNMRE GRKKERQQHN PPRRRTVSGS
860 870 880 890 900
VSGSSYSGSS SRSRSRSSSA SASRSGSHKS RSLSVSSVSS VSSASSSSSS
910 920 930 940 950
VRSADSDDMY ADLASPVSSA SSRSPTPGHP RKDRGPPRER GPNKERGKPP
960 970 980 990 1000
KKDEPFKDER KRVDPSGLPS KASSDMPRSG NRGHPMHPPP MGPPGGYGSH
1010 1020 1030 1040 1050
KDIKLTLLNK QQTDRSNRKR YFPSDKERPP SPLRKRMAMS PDGGRDRRMP
1060 1070 1080 1090 1100
GRPPMSPRME RPKGQGPRPM PSQGERKRPL SPPAKSSGKG PAAASAAKPP
1110 1120 1130 1140
APGAGSGSAS GSAPGKPSST LSRREELLKQ LKAVEDAIAR KRAKIPGK
Length:1,148
Mass (Da):129,172
Last modified:May 30, 2006 - v1
Checksum:iB3E0D362EF7C503A
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4IEF8A0A0R4IEF8_DANRE
Zinc finger CCCH domain-containing ...
zc3h18
1,134Annotation score:
A0A2R8QPT6A0A2R8QPT6_DANRE
Zinc finger CCCH domain-containing ...
zc3h18
1,097Annotation score:
Q1LUF0Q1LUF0_DANRE
Zinc finger CCCH domain-containing ...
zc3h18
218Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935038, BX950194 Genomic DNA Translation: CAK04265.1
BX950194, AL935038 Genomic DNA Translation: CAK04529.1
RefSeqiNP_001037804.1, NM_001044339.2
UniGeneiDr.159723
Dr.24473

Genome annotation databases

EnsembliENSDART00000090446; ENSDARP00000084879; ENSDARG00000062506
ENSDART00000141873; ENSDARP00000122210; ENSDARG00000062506
GeneIDi555770
KEGGidre:555770

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935038, BX950194 Genomic DNA Translation: CAK04265.1
BX950194, AL935038 Genomic DNA Translation: CAK04529.1
RefSeqiNP_001037804.1, NM_001044339.2
UniGeneiDr.159723
Dr.24473

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000122210

PTM databases

iPTMnetiQ1LUE5

Proteomic databases

PaxDbiQ1LUE5
PRIDEiQ1LUE5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000090446; ENSDARP00000084879; ENSDARG00000062506
ENSDART00000141873; ENSDARP00000122210; ENSDARG00000062506
GeneIDi555770
KEGGidre:555770

Organism-specific databases

CTDi124245
ZFINiZDB-GENE-050419-13 zc3h18

Phylogenomic databases

eggNOGiENOG410IJ7N Eukaryota
ENOG4111IXQ LUCA
GeneTreeiENSGT00730000111190
HOGENOMiHOG000155765
InParanoidiQ1LUE5
KOiK13092
OrthoDBiEOG091G03UA
PhylomeDBiQ1LUE5
TreeFamiTF327301

Miscellaneous databases

PROiPR:Q1LUE5

Gene expression databases

BgeeiENSDARG00000062506 Expressed in 29 organ(s), highest expression level in mature ovarian follicle
ExpressionAtlasiQ1LUE5 baseline

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiZCH18_DANRE
AccessioniPrimary (citable) accession number: Q1LUE5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 30, 2006
Last modified: September 12, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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