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Entry version 114 (02 Jun 2021)
Sequence version 1 (30 May 2006)
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Protein

Histone acetyltransferase KAT2B

Gene

kat2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a histone acetyltransferase (HAT) to promote transcriptional activation (By similarity).

Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles (By similarity).

Also acetylates non-histone proteins (PubMed:29174768).

Involved in heart and limb development by mediating acetylation of tbx5 (PubMed:29174768).

Also acetylates spermidine (By similarity).

Together with kat2a, required for growth and differentiation of craniofacial cartilage and bone by regulating acetylation of histone H3 at 'Lys-9' (H3K9ac) (PubMed:30424580).

By similarity2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei536Proton donor/acceptorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Acyltransferase, Transferase
Biological processBiological rhythms, Cell cycle, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-2032785, YAP1- and WWTR1 (TAZ)-stimulated gene expression
R-DRE-5250924, B-WICH complex positively regulates rRNA expression
R-DRE-5689901, Metalloprotease DUBs
R-DRE-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
R-DRE-8941856, RUNX3 regulates NOTCH signaling
R-DRE-9018519, Estrogen-dependent gene expression
R-DRE-9617629, Regulation of FOXO transcriptional activity by acetylation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone acetyltransferase KAT2BBy similarity (EC:2.3.1.48By similarity)
Alternative name(s):
Histone acetyltransferase PCAFBy similarity
Short name:
Histone acetylase PCAFBy similarity
Lysine acetyltransferase 2BBy similarity
P300/CBP-associated factorBy similarity
Short name:
P/CAFBy similarity
Spermidine acetyltransferase KAT2B (EC:2.3.1.57By similarity)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:kat2bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-060503-207, kat2b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Craniofacial cartilage and bone defects, characterized by shortening and hypoplastic nature of the cartilage elements and disruption of the posterior ceratobranchial cartilages (PubMed:30424580). Morpholino knockdown of kat2a and kat2b leads to impaired heart and limb development. Abnormal fin development is also observed (PubMed:29174768).2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004434481 – 796Histone acetyltransferase KAT2BAdd BLAST796

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q1LUC3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Widely expressed throughout the anterior head region, including the central nervous system, the eye and branchial arches at 24 hours post fertilization (hpf). Expressed strongly in the brain region, with expression extending posteriorly in the spinal cord. By 40-48 hpf, expression remains strongly expressed in the head region but is reduced throughout the rest of the embryo (PubMed:30424580). Expressed in the heart and tail regions throughout developmental stages (PubMed:29174768).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000062634, Expressed in retina and 24 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000085190

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q1LUC3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini469 – 617N-acetyltransferasePROSITE-ProRule annotationAdd BLAST149
Domaini704 – 774BromoPROSITE-ProRule annotationAdd BLAST71

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 32DisorderedSequence analysisAdd BLAST32
Regioni77 – 97DisorderedSequence analysisAdd BLAST21
Regioni371 – 408DisorderedSequence analysisAdd BLAST38
Regioni540 – 542Acetyl-CoA bindingBy similarity3
Regioni547 – 553Acetyl-CoA bindingBy similarity7
Regioni578 – 581Acetyl-CoA bindingBy similarity4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi80 – 95Pro residuesSequence analysisAdd BLAST16
Compositional biasi392 – 408Basic and acidic residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Bromodomain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1472, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154995

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015901_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q1LUC3

Identification of Orthologs from Complete Genome Data

More...
OMAi
DFAIGYF

Database of Orthologous Groups

More...
OrthoDBi
349249at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q1LUC3

TreeFam database of animal gene trees

More...
TreeFami
TF105399

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.920.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016181, Acyl_CoA_acyltransferase
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR037800, GCN5
IPR016376, GCN5/PCAF
IPR000182, GNAT_dom
IPR009464, PCAF_N

The PANTHER Classification System

More...
PANTHERi
PTHR45750, PTHR45750, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00583, Acetyltransf_1, 1 hit
PF00439, Bromodomain, 1 hit
PF06466, PCAF_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF003048, Histone_acetylase_PCAF, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00503, BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00297, BROMO, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47370, SSF47370, 1 hit
SSF55729, SSF55729, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 1 hit
PS51186, GNAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q1LUC3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSESTGIPQG SPAVGAAGSA PAAPGVGGTE CSGAAVGSAR IAVKKAQLRS
60 70 80 90 100
SPRPKKLEKL GVYSSCKAEG ACKCNGWKSQ NPPPTPPPPT PPRAEQPTAV
110 120 130 140 150
SLMEPCRSCS HALGDHVTHL ENVSEEEMNR LLGIVLDVEY LYTCVHKEED
160 170 180 190 200
PDTKQVYFSL FKLLRKCILQ MGRPVVEALE SPPFEKPSIE QGVNNFVQYK
210 220 230 240 250
FSHLPSKERQ TIVELAKMFL NQINYWQLET PSQKRQRAPD DDVAGYKVNY
260 270 280 290 300
TRWLCYCNVP QFCDSLPRYE ATQIFGRIFL RSVFTIMRKQ LLEQARQEKD
310 320 330 340 350
KLPPEKRTLI LTHFPKFLSM LEEEVYSHNS PIWSENFMIG LSGGQIPTVV
360 370 380 390 400
SAPPVNRSLY YSSSPAPVEL AGGGSVSPAR KTASVLEPNP GGEKRKPAEP
410 420 430 440 450
LSHEDSKRPR VVGDIPMELI NEVMSTITDP TAMLGPETSL LSAHSARDEA
460 470 480 490 500
ARLEERRGVI EFHVIGNSLN QKPNKKILMW LVGLQNVFSH QLPRMPKEYI
510 520 530 540 550
TRLVFDPKHK TLSLIKDGRV IGGICFRMFP TQGFTEIVFC AVTSNEQVKG
560 570 580 590 600
YGTHLMNHLK EYHIKHEILN FLTYADEYAI GYFKKQGFSK DIKVPKSKYV
610 620 630 640 650
GYIKDYEGAT LMGCELNPCI PYTEFSVIIK KQKEIIKKLI ERKQAQIRKV
660 670 680 690 700
YPGLSCFKEG VRQIAIESIP GIRETGWKPL GKSKELKDPD QLYSTLKNIL
710 720 730 740 750
TQVKSHPNAW PFMEPVKKNE APGYYQVIRF PMDLKTMSER LKSRYYTTRK
760 770 780 790
LFMADMQRIF TNCREYNPPE SEYYKCANLL EKFFYTKIKE AGLIDK
Length:796
Mass (Da):90,026
Last modified:May 30, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1B321F4A513B9E5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX950869 Genomic DNA No translation available.
BX957344 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001038499.1, NM_001045034.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000090757; ENSDARP00000085190; ENSDARG00000062634

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
563942

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:563942

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950869 Genomic DNA No translation available.
BX957344 Genomic DNA No translation available.
RefSeqiNP_001038499.1, NM_001045034.1

3D structure databases

SMRiQ1LUC3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000085190

Proteomic databases

PaxDbiQ1LUC3

Genome annotation databases

EnsembliENSDART00000090757; ENSDARP00000085190; ENSDARG00000062634
GeneIDi563942
KEGGidre:563942

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8850
ZFINiZDB-GENE-060503-207, kat2b

Phylogenomic databases

eggNOGiKOG1472, Eukaryota
GeneTreeiENSGT00940000154995
HOGENOMiCLU_015901_0_0_1
InParanoidiQ1LUC3
OMAiDFAIGYF
OrthoDBi349249at2759
PhylomeDBiQ1LUC3
TreeFamiTF105399

Enzyme and pathway databases

ReactomeiR-DRE-2032785, YAP1- and WWTR1 (TAZ)-stimulated gene expression
R-DRE-5250924, B-WICH complex positively regulates rRNA expression
R-DRE-5689901, Metalloprotease DUBs
R-DRE-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
R-DRE-8941856, RUNX3 regulates NOTCH signaling
R-DRE-9018519, Estrogen-dependent gene expression
R-DRE-9617629, Regulation of FOXO transcriptional activity by acetylation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q1LUC3

Gene expression databases

BgeeiENSDARG00000062634, Expressed in retina and 24 other tissues

Family and domain databases

Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR016181, Acyl_CoA_acyltransferase
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR037800, GCN5
IPR016376, GCN5/PCAF
IPR000182, GNAT_dom
IPR009464, PCAF_N
PANTHERiPTHR45750, PTHR45750, 1 hit
PfamiView protein in Pfam
PF00583, Acetyltransf_1, 1 hit
PF00439, Bromodomain, 1 hit
PF06466, PCAF_N, 1 hit
PIRSFiPIRSF003048, Histone_acetylase_PCAF, 1 hit
PRINTSiPR00503, BROMODOMAIN
SMARTiView protein in SMART
SM00297, BROMO, 1 hit
SUPFAMiSSF47370, SSF47370, 1 hit
SSF55729, SSF55729, 1 hit
PROSITEiView protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 1 hit
PS51186, GNAT, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKAT2B_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1LUC3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 28, 2018
Last sequence update: May 30, 2006
Last modified: June 2, 2021
This is version 114 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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