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Protein

Importin subunit alpha

Gene

NCU01249

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
ORF Names:NCU01249Imported
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)Imported
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000001805 Componenti: Chromosome 2, Linkage Group V

Organism-specific databases

EuPathDBiFungiDB:NCU01249

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ1K6K3
SMRiQ1K6K3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 58IBBInterPro annotationAdd BLAST58
Repeati124 – 166ARMPROSITE-ProRule annotationAdd BLAST43
Repeati166 – 208ARMPROSITE-ProRule annotationAdd BLAST43
Repeati335 – 367ARMPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili22 – 49Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoidiQ1K6K3
OMAiPYAITIE
OrthoDBiEOG092C1PRY

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 3 hits
PS51214 IBB, 1 hit

Sequencei

Sequence statusi: Complete.

Q1K6K3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADRYIPEHR RTQFKAKSAF KPDELRRRRE EQQVEIRKAK REENLAKRRG
60 70 80 90 100
IGAGDSRPGA SLGAAPDSDD ENPPTESQLS EDLPKMVEGV FSSEIDKQIQ
110 120 130 140 150
ATTKFRKLLS KERNPPIEEV IKTGVVGRFV EFLRSPHTLV QFEAAWALTN
160 170 180 190 200
IASGSATQTQ VVIEAGAVPI FVELLGSPEP DVREQAVWAL GNIAGDSPQC
210 220 230 240 250
RDYVLSCGAL RPLLTLLGDS RKLSMLRNAT WTLSNFCRGK TPQPDWNTIA
260 270 280 290 300
PALPVLAKLV YSLDDEVLID ACWAISYLSD GSNDKIQAVI EAGIPRRLVE
310 320 330 340 350
LLMHASTSVQ TPALRSVGNI VTGDDVQTQV IINCGALPCL LSLLSSNKDG
360 370 380 390 400
IRKEACWTIS NITAGNSAQI QSVIDANIIP PLIHLLSHAD LKTRKEACWA
410 420 430 440 450
ISNATSGGLQ KPDQIRYLVA QGCIKPLCDL LACPDNKIIQ VALDGLENIL
460 470 480 490 500
KVGELDKNAA GDGPDSINRY ALFIEECGGM EKIHDCQTNA NEEIYMKAYN
510 520 530 540
IIEKYFSDED EAGDEAMGAQ QQFGFGASGG AQQGGFNFGA NGTESMDM
Length:548
Mass (Da):59,697
Last modified:June 28, 2011 - v1
Checksum:i77EB61AA5273D504
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002240 Genomic DNA Translation: EAA31416.1
RefSeqiXP_960652.1, XM_955559.3

Genome annotation databases

EnsemblFungiiEAA31416; EAA31416; NCU01249
GeneIDi3876800
KEGGincr:NCU01249

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002240 Genomic DNA Translation: EAA31416.1
RefSeqiXP_960652.1, XM_955559.3

3D structure databases

ProteinModelPortaliQ1K6K3
SMRiQ1K6K3
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAA31416; EAA31416; NCU01249
GeneIDi3876800
KEGGincr:NCU01249

Organism-specific databases

EuPathDBiFungiDB:NCU01249

Phylogenomic databases

InParanoidiQ1K6K3
OMAiPYAITIE
OrthoDBiEOG092C1PRY

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 3 hits
PS51214 IBB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ1K6K3_NEUCR
AccessioniPrimary (citable) accession number: Q1K6K3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: October 10, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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