UniProtKB - Q1JPX9 (Q1JPX9_DANRE)
Protein
Submitted name:
Zgc:136493
Gene
zgc:136493
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- glyoxylate reductase (NADP) activity Source: GO_Central
- hydroxypyruvate reductase activity Source: GO_Central
- NAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: GO_Central
- protein homodimerization activity Source: GO_Central
Keywordsi
Molecular function | OxidoreductaseUniRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Zgc:136493Imported |
Gene namesi | ORF Names:zgc:136493Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio |
Organism-specific databases
ZFINi | ZDB-GENE-060512-216 zgc:136493 |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 45 – 322 | 2-Hacid_dhInterPro annotationAdd BLAST | 278 | |
Domaini | 112 – 291 | 2-Hacid_dh_CInterPro annotationAdd BLAST | 180 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0069 Eukaryota COG1052 LUCA |
HOGENOMi | HOG000136700 |
HOVERGENi | HBG104937 |
OrthoDBi | 1378766at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029752 D-isomer_DH_CS1 IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065 D_2_HYDROXYACID_DH_1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q1JPX9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEKPCILTKT LGAPGSIYKC FEPCIDKHFT IIPYERFVQR KEDFAAKIQA
60 70 80 90 100
VFSWGPNINV DRDLLQSLPN LKAVINGGVG VDHLDIPLIN SFGVKVSNTP
110 120 130 140 150
HVVDNATADI GMSLMLASAR KIIEGQHFSK FRESDDFPES TMGTDVSGAT
160 170 180 190 200
LGIIGMGRIG YKIAKRAQGF DMKILYHNRN RRPENEERAV GATYCASMTE
210 220 230 240 250
LLQRSDFVMV VVNLSPQTHK LISAKEFAMM RPYSTFINIS RGLVVDQDAL
260 270 280 290 300
VDALQKKMIR AAALDVTYPE PLPRDHPLLS FPNVIVMPHI GTHTLETSQL
310 320
MVERMVTNAL AILNEGQLPD EVKA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC116558 mRNA Translation: AAI16559.1 |
RefSeqi | NP_001038714.1, NM_001045249.1 |
UniGenei | Dr.29877 |
Genome annotation databases
GeneIDi | 692276 |
KEGGi | dre:692276 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC116558 mRNA Translation: AAI16559.1 |
RefSeqi | NP_001038714.1, NM_001045249.1 |
UniGenei | Dr.29877 |
3D structure databases
ProteinModelPortali | Q1JPX9 |
ModBasei | Search... |
MobiDBi | Search... |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
GeneIDi | 692276 |
KEGGi | dre:692276 |
Organism-specific databases
ZFINi | ZDB-GENE-060512-216 zgc:136493 |
Phylogenomic databases
eggNOGi | KOG0069 Eukaryota COG1052 LUCA |
HOGENOMi | HOG000136700 |
HOVERGENi | HBG104937 |
OrthoDBi | 1378766at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029752 D-isomer_DH_CS1 IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065 D_2_HYDROXYACID_DH_1, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | Q1JPX9_DANRE | |
Accessioni | Q1JPX9Primary (citable) accession number: Q1JPX9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 13, 2006 |
Last sequence update: | June 13, 2006 | |
Last modified: | January 16, 2019 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |