Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Deinococcus geothermalis (strain DSM 11300)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei82Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processDNA damage, DNA repair

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
Ordered Locus Names:Dgeo_2059
OrganismiDeinococcus geothermalis (strain DSM 11300)
Taxonomic identifieri319795 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002431 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001997751 – 245Uracil-DNA glycosylaseAdd BLAST245

Interactioni

Protein-protein interaction databases

STRINGi319795.Dgeo_2059

Structurei

3D structure databases

ProteinModelPortaliQ1IWN1
SMRiQ1IWN1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D5S Bacteria
COG0692 LUCA
HOGENOMiHOG000229528
KOiK03648
OMAiQANGLCF
OrthoDBiPOG091H03VL

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.10, 1 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
TIGRFAMsiTIGR00628 ung, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q1IWN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDPASLFGL PPDPDAAPPV HLPGDWDEVL RGETSQPYFR ELWAFVQRER
60 70 80 90 100
EAGPVYPAPE DLFSALRLTP YRDVKVLILG QDPYHGAGQA HGLSFSVRPG
110 120 130 140 150
VRVPPSLQNI YKELRDDVGF KPPRHGSLVS WARQGVLLLN AVLTVREGEP
160 170 180 190 200
NSHAGKGWES FTDAIIRAVN EKPTRVVFVL WGAYARKKAK LVTQPQHVII
210 220 230 240
ESAHPSPLSV AKFLGTRPFS RINAALEAAG ETPIDWQLPA EPEVA
Length:245
Mass (Da):27,000
Last modified:June 13, 2006 - v1
Checksum:i62957735DB79DA0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000359 Genomic DNA Translation: ABF46353.1

Genome annotation databases

EnsemblBacteriaiABF46353; ABF46353; Dgeo_2059
KEGGidge:Dgeo_2059

Similar proteinsi

Entry informationi

Entry nameiUNG_DEIGD
AccessioniPrimary (citable) accession number: Q1IWN1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 13, 2006
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health