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Entry version 80 (12 Aug 2020)
Sequence version 1 (27 Jun 2006)
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Protein

Outer envelope pore protein 24A, chloroplastic

Gene

OEP24A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

High-conductance voltage-dependent solute channel with a slight selectivity for cations transporting triosephosphates, dicarboxylic acids, ATP, inorganic phosphate (Pi), sugars, and positively or negatively charged amino acids.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionPorin
Biological processIon transport, Transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.B.28.1.4, the plastid outer envelope porin of 24 kda (oep24) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Outer envelope pore protein 24A, chloroplastic
Alternative name(s):
Chloroplastic outer envelope pore protein of 24 kDa A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OEP24A
Ordered Locus Names:At1g45170
ORF Names:F27F5.25
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G45170

The Arabidopsis Information Resource

More...
TAIRi
locus:2028210, AT1G45170

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 2CytoplasmicSequence analysis2
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3 – 12Beta stranded; Name=1Sequence analysis10
Topological domaini13 – 17Chloroplast intermembraneSequence analysis5
Transmembranei18 – 27Beta stranded; Name=2Sequence analysis10
Topological domaini28 – 31CytoplasmicSequence analysis4
Transmembranei32 – 41Beta stranded; Name=3Sequence analysis10
Topological domaini42 – 54Chloroplast intermembraneSequence analysisAdd BLAST13
Transmembranei55 – 63Beta stranded; Name=4Sequence analysis9
Topological domaini64 – 69CytoplasmicSequence analysis6
Transmembranei70 – 79Beta stranded; Name=5Sequence analysis10
Topological domaini80 – 92Chloroplast intermembraneSequence analysisAdd BLAST13
Transmembranei93 – 102Beta stranded; Name=6Sequence analysis10
Topological domaini103 – 107CytoplasmicSequence analysis5
Transmembranei108 – 117Beta stranded; Name=7Sequence analysis10
Topological domaini118 – 121Chloroplast intermembraneSequence analysis4
Transmembranei122 – 131Beta stranded; Name=8Sequence analysis10
Topological domaini132 – 143CytoplasmicSequence analysisAdd BLAST12
Transmembranei144 – 155Beta stranded; Name=9Sequence analysisAdd BLAST12
Topological domaini156 – 158Chloroplast intermembraneSequence analysis3
Transmembranei159 – 167Beta stranded; Name=10Sequence analysis9
Topological domaini168 – 169CytoplasmicSequence analysis2
Transmembranei170 – 178Beta stranded; Name=11Sequence analysis9
Topological domaini179 – 201Chloroplast intermembraneSequence analysisAdd BLAST23
Transmembranei202 – 211Beta stranded; Name=12Sequence analysis10
Topological domaini212 – 213CytoplasmicSequence analysis2

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Plastid outer membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004155361 – 213Outer envelope pore protein 24A, chloroplasticAdd BLAST213

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q1H5C9

PRoteomics IDEntifications database

More...
PRIDEi
Q1H5C9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
249366 [Q1H5C9-1]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q1H5C9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q1H5C9, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homooligomers form large rather nonselective pores in plastidial outer membranes.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
26310, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q1H5C9, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT1G45170.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane beta strand

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QUHD, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q1H5C9

Identification of Orthologs from Complete Genome Data

More...
OMAi
MTDATFI

Database of Orthologous Groups

More...
OrthoDBi
1227223at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q1H5C9

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR034626, OEP24

The PANTHER Classification System

More...
PANTHERi
PTHR35284, PTHR35284, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q1H5C9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMKASFKGKF DVDKSGSVAS LTFNAGNAKL RATMTDASFV AGPSFNGLSL
60 70 80 90 100
AVEKPGFFII DYNVPKKDVR FQFMNTIRIA EKPLNLTYIH MRGDNRTIVD
110 120 130 140 150
GSFVIDPANK LSANYMVGTK NCKLKYTYVH GGIATFEPCY DVAKNMWDFA
160 170 180 190 200
ISHKLYGGDN LKATYQTSSK MLGLEWSNNS KSTGSFKVCA SMNLAEELKP
210
PKLTAETTWN LEL
Length:213
Mass (Da):23,591
Last modified:June 27, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i693B6E72D8F362D0
GO
Isoform 2 (identifier: Q1H5C9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     117-162: Missing.

Show »
Length:167
Mass (Da):18,411
Checksum:i0698361273D9B8C8
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF69166 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAC43078 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_042274117 – 162Missing in isoform 2. CuratedAdd BLAST46

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC007915 Genomic DNA Translation: AAF69166.1 Different initiation.
CP002684 Genomic DNA Translation: AEE32089.1
CP002684 Genomic DNA Translation: AEE32090.1
BT025535 mRNA Translation: ABF58953.1
AK118473 mRNA Translation: BAC43078.1 Different initiation.

Protein sequence database of the Protein Information Resource

More...
PIRi
A96510

NCBI Reference Sequences

More...
RefSeqi
NP_001077680.1, NM_001084211.1 [Q1H5C9-2]
NP_175131.3, NM_103591.4 [Q1H5C9-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G45170.1; AT1G45170.1; AT1G45170 [Q1H5C9-1]
AT1G45170.2; AT1G45170.2; AT1G45170 [Q1H5C9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
841085

Gramene; a comparative resource for plants

More...
Gramenei
AT1G45170.1; AT1G45170.1; AT1G45170 [Q1H5C9-1]
AT1G45170.2; AT1G45170.2; AT1G45170 [Q1H5C9-2]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G45170

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007915 Genomic DNA Translation: AAF69166.1 Different initiation.
CP002684 Genomic DNA Translation: AEE32089.1
CP002684 Genomic DNA Translation: AEE32090.1
BT025535 mRNA Translation: ABF58953.1
AK118473 mRNA Translation: BAC43078.1 Different initiation.
PIRiA96510
RefSeqiNP_001077680.1, NM_001084211.1 [Q1H5C9-2]
NP_175131.3, NM_103591.4 [Q1H5C9-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi26310, 2 interactors
IntActiQ1H5C9, 2 interactors
STRINGi3702.AT1G45170.1

Protein family/group databases

TCDBi1.B.28.1.4, the plastid outer envelope porin of 24 kda (oep24) family

Proteomic databases

PaxDbiQ1H5C9
PRIDEiQ1H5C9
ProteomicsDBi249366 [Q1H5C9-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
841085

Genome annotation databases

EnsemblPlantsiAT1G45170.1; AT1G45170.1; AT1G45170 [Q1H5C9-1]
AT1G45170.2; AT1G45170.2; AT1G45170 [Q1H5C9-2]
GeneIDi841085
GrameneiAT1G45170.1; AT1G45170.1; AT1G45170 [Q1H5C9-1]
AT1G45170.2; AT1G45170.2; AT1G45170 [Q1H5C9-2]
KEGGiath:AT1G45170

Organism-specific databases

AraportiAT1G45170
TAIRilocus:2028210, AT1G45170

Phylogenomic databases

eggNOGiENOG502QUHD, Eukaryota
InParanoidiQ1H5C9
OMAiMTDATFI
OrthoDBi1227223at2759
PhylomeDBiQ1H5C9

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q1H5C9

Gene expression databases

ExpressionAtlasiQ1H5C9, baseline and differential
GenevisibleiQ1H5C9, AT

Family and domain databases

InterProiView protein in InterPro
IPR034626, OEP24
PANTHERiPTHR35284, PTHR35284, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOP24A_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1H5C9
Secondary accession number(s): A8MR28, Q8GX28, Q9MAJ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: June 27, 2006
Last modified: August 12, 2020
This is version 80 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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