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Protein

Guanylate kinase

Gene

gmk

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLDEL390333:LDB_RS06075-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:Ldb1415
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Taxonomic identifieri390333 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001259 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663391 – 204Guanylate kinaseAdd BLAST204

Proteomic databases

PRIDEiQ1G9H8

Interactioni

Protein-protein interaction databases

STRINGi390333.Ldb1415

Structurei

3D structure databases

ProteinModelPortaliQ1G9H8
SMRiQ1G9H8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 184Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037639
KOiK00942
OMAiAGNYYGT

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1G9H8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKGLLLVL SGPSGVGKGT VKSAIVEHKV FPFEYSVSMT TRKPREGEVN
60 70 80 90 100
GKDYYFVTRE EFKQAIADNQ LLEYNEYVGN LYGTPLGPVK EMLAAGKDVL
110 120 130 140 150
LEIDVNGART VRQQMPEGVF IFLTPPDLHT LRDRLEHRGT ESEDVIRGRI
160 170 180 190 200
AQARKEILVM QDYDYAVVND TVANAVNHIK AIVDAEHVSV RRVIDDYRKM

VKED
Length:204
Mass (Da):22,967
Last modified:June 27, 2006 - v1
Checksum:iF19A3EA20916852F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR954253 Genomic DNA Translation: CAI98216.1
RefSeqiWP_011544043.1, NZ_JQAV01000009.1

Genome annotation databases

EnsemblBacteriaiCAI98216; CAI98216; Ldb1415
GeneIDi4085315
KEGGildb:Ldb1415
PATRICifig|390333.13.peg.1953

Similar proteinsi

Entry informationi

Entry nameiKGUA_LACDA
AccessioniPrimary (citable) accession number: Q1G9H8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: June 27, 2006
Last modified: June 20, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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