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Entry version 125 (29 Sep 2021)
Sequence version 1 (11 Jul 2006)
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Protein

Lysine-rich nucleolar protein 1

Gene

KNOP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q1ED39

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lysine-rich nucleolar protein 1
Alternative name(s):
Protein FAM191A
Testis-specific gene 118 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KNOP1
Synonyms:C16orf88, FAM191A, TSG118
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:34404, KNOP1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q1ED39

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000103550

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
400506

Open Targets

More...
OpenTargetsi
ENSG00000103550

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162378471

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q1ED39, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KNOP1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
121940661

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003219381 – 458Lysine-rich nucleolar protein 1Add BLAST458

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki7Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei42PhosphoserineCombined sources1
Modified residuei50PhosphoserineCombined sources1
Cross-linki101Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei111PhosphoserineCombined sources1
Cross-linki130Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei132PhosphoserineCombined sources1
Cross-linki249Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki249Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei265PhosphoserineCombined sources1
Cross-linki275Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki287Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki305Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei308PhosphothreonineCombined sources1
Modified residuei310PhosphothreonineCombined sources1
Cross-linki319Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki353Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki373Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki375Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki407Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei430Omega-N-methylarginineCombined sources1
Cross-linki442Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q1ED39

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q1ED39

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q1ED39

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q1ED39

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q1ED39

PeptideAtlas

More...
PeptideAtlasi
Q1ED39

PRoteomics IDEntifications database

More...
PRIDEi
Q1ED39

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
61208

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q1ED39, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q1ED39

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q1ED39

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000103550, Expressed in tendon of biceps brachii and 231 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q1ED39, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q1ED39, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000103550, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ZNF106.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
134613, 175 interactors

Protein interaction database and analysis system

More...
IntActi
Q1ED39, 67 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000219837

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q1ED39, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q1ED39

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 21DisorderedSequence analysisAdd BLAST21
Regioni46 – 305DisorderedSequence analysisAdd BLAST260
Regioni306 – 458Interaction with ZNF106By similarityAdd BLAST153
Regioni336 – 355DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi73 – 120Basic and acidic residuesSequence analysisAdd BLAST48
Compositional biasi172 – 200Basic and acidic residuesSequence analysisAdd BLAST29
Compositional biasi201 – 215Basic residuesSequence analysisAdd BLAST15
Compositional biasi234 – 251Basic and acidic residuesSequence analysisAdd BLAST18

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S1WB, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00500000044955

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_048750_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q1ED39

Identification of Orthologs from Complete Genome Data

More...
OMAi
AMSWKYN

Database of Orthologous Groups

More...
OrthoDBi
1055972at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q1ED39

TreeFam database of animal gene trees

More...
TreeFami
TF336149

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028124, SMAP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15477, SMAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q1ED39-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MITKTHKVDL GLPEKKKKKK VVKEPETRYS VLNNDDYFAD VSPLRATSPS
60 70 80 90 100
KSVAHGQAPE MPLVKKKKKK KKGVSTLCEE HVEPETTLPA RRTEKSPSLR
110 120 130 140 150
KQVFGHLEFL SGEKKNKKSP LAMSHASGVK TSPDPRQGEE ETRVGKKLKK
160 170 180 190 200
HKKEKKGAQD PTAFSVQDPW FCEAREARDV GDTCSVGKKD EEQAALGQKR
210 220 230 240 250
KRKSPREHNG KVKKKKKIHQ EGDALPGHSK PSRSMESSPR KGSKKKPVKV
260 270 280 290 300
EAPEYIPISD DPKASAKKKM KSKKKVEQPV IEEPALKRKK KKKRKESGVA
310 320 330 340 350
GDPWKEETDT DLEVVLEKKG NMDEAHIDQV RRKALQEEID RESGKTEASE
360 370 380 390 400
TRKWTGTQFG QWDTAGFENE DQKLKFLRLM GGFKNLSPSF SRPASTIARP
410 420 430 440 450
NMALGKKAAD SLQQNLQRDY DRAMSWKYSR GAGLGFSTAP NKIFYIDRNA

SKSVKLED
Length:458
Mass (Da):51,589
Last modified:July 11, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF3935374029D61D9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BNU8H3BNU8_HUMAN
Lysine-rich nucleolar protein 1
KNOP1
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BPL4H3BPL4_HUMAN
Lysine-rich nucleolar protein 1
KNOP1
199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BMC9H3BMC9_HUMAN
Lysine-rich nucleolar protein 1
KNOP1
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC05805 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence AAH89430 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06171628R → Q. Corresponds to variant dbSNP:rs11640454Ensembl.1
Natural variantiVAR_039387266A → V. Corresponds to variant dbSNP:rs2074036Ensembl.1
Natural variantiVAR_061717276V → A. Corresponds to variant dbSNP:rs28424569Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC002550 Genomic DNA Translation: AAC05805.1 Different initiation.
BC089430 mRNA Translation: AAH89430.1 Sequence problems.
BC117562 mRNA Translation: AAI17563.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42127.1

NCBI Reference Sequences

More...
RefSeqi
NP_001013009.2, NM_001012991.2
NP_001335457.1, NM_001348528.1
NP_001335458.1, NM_001348529.1
NP_001335459.1, NM_001348530.1
NP_001335460.1, NM_001348531.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000219837; ENSP00000219837; ENSG00000103550

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
400506

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:400506

UCSC genome browser

More...
UCSCi
uc002dgq.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002550 Genomic DNA Translation: AAC05805.1 Different initiation.
BC089430 mRNA Translation: AAH89430.1 Sequence problems.
BC117562 mRNA Translation: AAI17563.1
CCDSiCCDS42127.1
RefSeqiNP_001013009.2, NM_001012991.2
NP_001335457.1, NM_001348528.1
NP_001335458.1, NM_001348529.1
NP_001335459.1, NM_001348530.1
NP_001335460.1, NM_001348531.1

3D structure databases

SMRiQ1ED39
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi134613, 175 interactors
IntActiQ1ED39, 67 interactors
STRINGi9606.ENSP00000219837

PTM databases

GlyGeniQ1ED39, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ1ED39
PhosphoSitePlusiQ1ED39

Genetic variation databases

BioMutaiKNOP1
DMDMi121940661

Proteomic databases

EPDiQ1ED39
jPOSTiQ1ED39
MassIVEiQ1ED39
MaxQBiQ1ED39
PaxDbiQ1ED39
PeptideAtlasiQ1ED39
PRIDEiQ1ED39
ProteomicsDBi61208

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
52534, 18 antibodies

The DNASU plasmid repository

More...
DNASUi
400506

Genome annotation databases

EnsembliENST00000219837; ENSP00000219837; ENSG00000103550
GeneIDi400506
KEGGihsa:400506
UCSCiuc002dgq.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
400506
DisGeNETi400506

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KNOP1
HGNCiHGNC:34404, KNOP1
HPAiENSG00000103550, Low tissue specificity
neXtProtiNX_Q1ED39
OpenTargetsiENSG00000103550
PharmGKBiPA162378471
VEuPathDBiHostDB:ENSG00000103550

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502S1WB, Eukaryota
GeneTreeiENSGT00500000044955
HOGENOMiCLU_048750_0_0_1
InParanoidiQ1ED39
OMAiAMSWKYN
OrthoDBi1055972at2759
PhylomeDBiQ1ED39
TreeFamiTF336149

Enzyme and pathway databases

PathwayCommonsiQ1ED39

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
400506, 6 hits in 1008 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
KNOP1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
400506
PharosiQ1ED39, Tdark

Protein Ontology

More...
PROi
PR:Q1ED39
RNActiQ1ED39, protein

Gene expression databases

BgeeiENSG00000103550, Expressed in tendon of biceps brachii and 231 other tissues
ExpressionAtlasiQ1ED39, baseline and differential
GenevisibleiQ1ED39, HS

Family and domain databases

InterProiView protein in InterPro
IPR028124, SMAP_dom
PfamiView protein in Pfam
PF15477, SMAP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKNOP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1ED39
Secondary accession number(s): O43328, Q5FWF3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: July 11, 2006
Last modified: September 29, 2021
This is version 125 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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