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Entry version 97 (29 Sep 2021)
Sequence version 1 (11 Jul 2006)
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Protein
Submitted name:

Membrane protein

Gene

MXAN_4075

Organism
Myxococcus xanthus (strain DK1622)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.145.1, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Membrane proteinImported
Submitted name:
Putative membrane proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:MXAN_4075Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMyxococcus xanthus (strain DK1622)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri246197 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeMyxococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002402 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei20 – 41HelicalSequence analysisAdd BLAST22
Transmembranei61 – 85HelicalSequence analysisAdd BLAST25
Transmembranei106 – 133HelicalSequence analysisAdd BLAST28
Transmembranei153 – 177HelicalSequence analysisAdd BLAST25
Transmembranei184 – 202HelicalSequence analysisAdd BLAST19
Transmembranei250 – 267HelicalSequence analysisAdd BLAST18
Transmembranei323 – 345HelicalSequence analysisAdd BLAST23
Transmembranei365 – 382HelicalSequence analysisAdd BLAST18
Transmembranei410 – 432HelicalSequence analysisAdd BLAST23
Transmembranei452 – 469HelicalSequence analysisAdd BLAST18
Transmembranei474 – 494HelicalSequence analysisAdd BLAST21
Transmembranei527 – 545HelicalSequence analysisAdd BLAST19
Transmembranei566 – 587HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
246197.MXAN_4075

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini869 – 1048Peptidase_M1InterPro annotationAdd BLAST180

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni750 – 776DisorderedSequence analysisAdd BLAST27

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0308, Bacteria
COG1277, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007999_0_0_7

Identification of Orthologs from Complete Genome Data

More...
OMAi
PYNKLID

Database of Orthologous Groups

More...
OrthoDBi
771837at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.390.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014782, Peptidase_M1_dom
IPR027268, Peptidase_M4/M1_CTD_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01433, Peptidase_M1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q1D520-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFTALLTFEL RRRVKMISTW VYALMLAAAA ALMTLAIGAV FKGFSVASGP
60 70 80 90 100
ELVRVNSPHT VFSFTISLAY FGLFMVAAVF GQAAYQDFGH NTWMLIFTKN
110 120 130 140 150
VKKGPYLLGR FLGAYLFSAV LMLAIIPGLM VGAAGVWLVD ADRLAPFQLT
160 170 180 190 200
SYLWPYVIGV WPTLFFAGAV FFSLAALTRR MAPVYVGVVV LVMGYLTLSA
210 220 230 240 250
AMSDVQHQDL ASLLDPFGFL TFENATRYWT AAERNQDHVP FAGLLLANRL
260 270 280 290 300
LWSVVGAALL GLAVLRFRTT VEEQRGRGTR KEKEAPAPVA IPTTLASPTT
310 320 330 340 350
GSWLRTAFAT SWLAYRDILR SPVFWSFVVA GLAMGTMGIS ISKQIYGTAT
360 370 380 390 400
WPVTWQVLET ATRTFQPFLL ITITFYAGEL VWKERDAGLA DIVDATRVPS
410 420 430 440 450
WVTYGAKLGA LLLVAFSLKA VALLSALLSQ VLRGYVDIEW NLYATQLFLL
460 470 480 490 500
DFPHDALLCV LAFFAQVLIH QKYLAYLVMV LYFVLQAALG LMGVEDLLVR
510 520 530 540 550
YGSEPTLRYS DLNRFGSIIP ALVWHRVYWY GLAALLVAVG YLLTVRGLEA
560 570 580 590 600
RWKQRWAAAK ARRTGAWTAA AALSLCVFIG AGAFIYYNTH ILNPYITRKD
610 620 630 640 650
RERQQARYEK EYASYAALPH PRITAAKVTF HIHPEELRLE ALGSYRIRNK
660 670 680 690 700
TDAPISKVML NLPDDARVRG LSLAGVTKPA MHDAELGIFI YELPTPLAPG
710 720 730 740 750
ADSAIVFDLE FGTKGFKHGG ARTDIVGNGT FFDNMKLPVL GYQTGAELED
760 770 780 790 800
DRDRKDYGLP PRERLPDRDD PKAKQDNYIR QDSDFIAFEA TVSTAKDQIA
810 820 830 840 850
IAPGYLEKEW TEGNRRFFHY RMDKPILNFF SVLSARYEVM RDTWRDVKLE
860 870 880 890 900
IYHHPTHTFA LDRMMRGMKD TLEYCSENFG PYQHRQARIL EFPRYASFAQ
910 920 930 940 950
SFPNTIPYSE ALGFIARVED GRADDVDYPY YVTAHEIAHQ WWAHQVVGAR
960 970 980 990 1000
AQGATMTSET MSQYAALMVM KHRFGPMKMK RFLKFELDRY LAARAFESKK
1010 1020 1030 1040 1050
EVPLARVEQQ LYIHYQKGSL VMYALQDFIG EERVNRALRR YVEKVRFQGP
1060 1070 1080 1090 1100
PYTGSSELLG FLREETPPEY QYLIEDLFEN ITLYDNRAVS AQVRQNDQGT
1110 1120 1130 1140 1150
WDVTLKVKSK KYRAGEKGEQ TEVDFNDWMD VGALDERGEA IFLEKRRVTK
1160 1170 1180 1190 1200
GESEFTFTVP VKPAQVGIDP LNVLIDRTST DNVTEPTVAS AVALGSPSTP
Length:1,200
Mass (Da):135,264
Last modified:July 11, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6AA213744049AF53
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000113 Genomic DNA Translation: ABF86972.1
KX622595 Genomic DNA Translation: APZ78765.1

NCBI Reference Sequences

More...
RefSeqi
WP_011554082.1, NC_008095.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ABF86972; ABF86972; MXAN_4075

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
41361405

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mxa:MXAN_4075

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000113 Genomic DNA Translation: ABF86972.1
KX622595 Genomic DNA Translation: APZ78765.1
RefSeqiWP_011554082.1, NC_008095.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi246197.MXAN_4075

Protein family/group databases

TCDBi3.A.1.145.1, the atp-binding cassette (abc) superfamily

Genome annotation databases

EnsemblBacteriaiABF86972; ABF86972; MXAN_4075
GeneIDi41361405
KEGGimxa:MXAN_4075

Phylogenomic databases

eggNOGiCOG0308, Bacteria
COG1277, Bacteria
HOGENOMiCLU_007999_0_0_7
OMAiPYNKLID
OrthoDBi771837at2

Family and domain databases

Gene3Di1.10.390.10, 1 hit
InterProiView protein in InterPro
IPR014782, Peptidase_M1_dom
IPR027268, Peptidase_M4/M1_CTD_sf
PfamiView protein in Pfam
PF01433, Peptidase_M1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ1D520_MYXXD
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q1D520
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: September 29, 2021
This is version 97 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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