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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Mycobacterium sp. (strain MCS)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair, DNA replication, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:Mmcs_0004
OrganismiMycobacterium sp. (strain MCS)
Taxonomic identifieri164756 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000485451 – 380DNA replication and repair protein RecFAdd BLAST380

Structurei

3D structure databases

SMRiQ1BG58
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000269561
KOiK03629
OMAiGQQKSFL

Family and domain databases

HAMAPiMF_00365 RecF, 1 hit
InterProiView protein in InterPro
IPR001238 DNA-binding_RecF
IPR018078 DNA-binding_RecF_CS
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
PANTHERiPTHR32182:SF0 PTHR32182:SF0, 1 hit
PfamiView protein in Pfam
PF02463 SMC_N, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
TIGRFAMsiTIGR00611 recf, 1 hit
PROSITEiView protein in PROSITE
PS00617 RECF_1, 1 hit
PS00618 RECF_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1BG58-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFVRHLTLTD FRSWARADLE LEPGRTVFVG PNGFGKTNLV EALWYSATLG
60 70 80 90 100
SHRVASDAPL IRVGAPRAVV STIVVNEGRE LAVDLEITTG RANKARLNRS
110 120 130 140 150
PVRSPREVLG VLRAVLFAPE DLALVRGDPG ERRRYLDELA TTRRPSIAGV
160 170 180 190 200
RADYDRVIRQ RTALLKSAAG ARYRGDRSVL ETLDVWDGHL AAHGALLMAA
210 220 230 240 250
RADLVHHLAP EVEKAYQLLA PGSRPAAIRY RTSIDAEDDV SAEYYEAALL
260 270 280 290 300
DAMTRRRDAE LERGVCLVGP HRDDLELRLG DQMAKGYASH GESWSMALSL
310 320 330 340 350
RLAAYELLRT DGSDPVLLLD DVFAELDAAR RRALAEVAAS AEQVLVTAAV
360 370 380
AEDIPADWDA RRIMIRMQDD DDGRVSMVES
Length:380
Mass (Da):41,879
Last modified:July 11, 2006 - v1
Checksum:iF0EE31194BFFA861
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000384 Genomic DNA Translation: ABG06126.1
RefSeqiWP_011557432.1, NC_008146.1

Genome annotation databases

EnsemblBacteriaiABG06126; ABG06126; Mmcs_0004
GeneIDi32418846
KEGGimmc:Mmcs_0004

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000384 Genomic DNA Translation: ABG06126.1
RefSeqiWP_011557432.1, NC_008146.1

3D structure databases

SMRiQ1BG58
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG06126; ABG06126; Mmcs_0004
GeneIDi32418846
KEGGimmc:Mmcs_0004

Phylogenomic databases

HOGENOMiHOG000269561
KOiK03629
OMAiGQQKSFL

Family and domain databases

HAMAPiMF_00365 RecF, 1 hit
InterProiView protein in InterPro
IPR001238 DNA-binding_RecF
IPR018078 DNA-binding_RecF_CS
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
PANTHERiPTHR32182:SF0 PTHR32182:SF0, 1 hit
PfamiView protein in Pfam
PF02463 SMC_N, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
TIGRFAMsiTIGR00611 recf, 1 hit
PROSITEiView protein in PROSITE
PS00617 RECF_1, 1 hit
PS00618 RECF_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRECF_MYCSS
AccessioniPrimary (citable) accession number: Q1BG58
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: October 10, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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