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Protein
Submitted name:

CARD15

Gene

nod2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • CARD domain binding Source: ZFIN
  • protein heterodimerization activity Source: ZFIN

GO - Biological processi

  • defense response to bacterium Source: ZFIN
  • defense response to virus Source: ZFIN
  • regulation of apoptotic process Source: InterPro
  • regulation of transcription, DNA-templated Source: ZFIN
  • response to bacterium Source: ZFIN

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
CARD15Imported
Gene namesi
Name:nod2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-061108-4 nod2

Subcellular locationi

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ1AMZ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 73CARDInterPro annotationAdd BLAST73
Domaini96 – 175CARDInterPro annotationAdd BLAST80
Domaini260 – 396NACHTInterPro annotationAdd BLAST137

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4308 Eukaryota
ENOG410ZBX3 LUCA
HOGENOMiHOG000113814
HOVERGENiHBG050792
PhylomeDBiQ1AMZ9

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR007111 NACHT_NTPase
PfamiView protein in Pfam
PF00619 CARD, 2 hits
PF13516 LRR_6, 3 hits
PF05729 NACHT, 1 hit
SUPFAMiSSF47986 SSF47986, 2 hits
PROSITEiView protein in PROSITE
PS50209 CARD, 2 hits
PS50837 NACHT, 1 hit

Sequencei

Sequence statusi: Fragment.

Q1AMZ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
RAELLAVLWG GGSDEPLESV LDLLLAQEVL VWEDYLRVRV AEKPLCANIR
60 70 80 90 100
QLLDLVYDKG EDACSYFLAA IEQELAEEQK AGLCFGNGCV MVGKDRPATA
110 120 130 140 150
TSTLLADRPM LVRRLRDNID GALNILLTTG CFSIKDCDSV QLPVYTPSQQ
160 170 180 190 200
VRRLLDQVKF KGETAAKTLL EYLEQPEPTS PISAEKENTP SADCLVYKKL
210 220 230 240 250
RSSVASQSLF LSTYGGTGRF SLDDIYTDGH LEVMNSSGET TTLGLEDVVG
260 270 280 290 300
PMGTLNEDAD TVLVSGEAGS GKSTLVQRLH LLWAREALLL NTFLLFPFSC
310 320 330 340 350
RKLNAEHREL SLKELLFLHC CWPDRNQDEV FQFILDHPHL VLFTFDGLDE
360 370 380 390 400
FKLGFTDEER HCCPTKQVPI PVLLFNLLQG TLMKGVMKVV TSRPHAVGPS
410 420 430 440 450
LKRYLRKEVL LKGFSPGGID CFVKKHYSDP AMATRVIESV QGNTALLGLC
460 470 480 490 500
HIPVFCWIVI KCYQELLAGQ DGIPQTITDV YLLVLQHFFQ RKSSQPQSGL
510 520 530 540 550
GKAWLAEHLD TVLKLGELAL EGLQTSCYVF SGYELQRNRI TEQDVGIGFL
560 570 580 590 600
IYCSDISVND CKRYEFLHIT LQCFFAALYV ILNRNNDRSA ISRLFQPRNR
610 620 630 640 650
QVSGLSQSCL GQCMDHSVEE SHEAETANLQ ITAQFVSGLL SQRHNNLFLE
660 670 680 690 700
CCPAVVRERN VKQVVKSLSK RMQRHFKSIP RPVEGEKKSM HAMPSFVWLI
710 720 730 740 750
KCIYELQDNS IAQDAMAKLD VEHLKLTYCN IGPVECTALA YVLKNLRKPV
760 770 780 790 800
GLQLDNNSVG DVGVEQLLPC LPMCHSLYLR NNNISDEGIR KLLEKGIECE
810 820 830 840 850
NFQKIALFNN KLTDTCTQYF SCLLKSKQNF LALRLGNNNI TSVGAEQLAE
860 870 880 890 900
GLSYNQSLQF LGLWGNKVGD RGAEVLADAL TNSKTLIWLS LVDNGVGSAG
910 920 930 940 950
ACALAKFIRQ NKSLEELWLN KNSICKEGVD CLIEALKMNT SVKKVWLRGN
960
NLSPQEEEQL SQQECRLTF
Length:969
Mass (Da):108,367
Last modified:July 11, 2006 - v1
Checksum:iA39DDA1D3D9B0FE8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ060248 mRNA Translation: AAY97879.1
UniGeneiDr.93177

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ060248 mRNA Translation: AAY97879.1
UniGeneiDr.93177

3D structure databases

ProteinModelPortaliQ1AMZ9
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-061108-4 nod2

Phylogenomic databases

eggNOGiKOG4308 Eukaryota
ENOG410ZBX3 LUCA
HOGENOMiHOG000113814
HOVERGENiHBG050792
PhylomeDBiQ1AMZ9

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR007111 NACHT_NTPase
PfamiView protein in Pfam
PF00619 CARD, 2 hits
PF13516 LRR_6, 3 hits
PF05729 NACHT, 1 hit
SUPFAMiSSF47986 SSF47986, 2 hits
PROSITEiView protein in PROSITE
PS50209 CARD, 2 hits
PS50837 NACHT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ1AMZ9_DANRE
AccessioniPrimary (citable) accession number: Q1AMZ9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: June 20, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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