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Entry version 58 (12 Aug 2020)
Sequence version 1 (11 Jul 2006)
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Protein
Submitted name:

Cadherin-like protein

Gene

BtR

Organism
Helicoverpa armigera (Cotton bollworm) (Heliothis armigera)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cadherin-like proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BtRImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHelicoverpa armigera (Cotton bollworm) (Heliothis armigera)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29058 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaNoctuoideaNoctuidaeHeliothinaeHelicoverpa

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1580 – 1604HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500418743023 – 1730Sequence analysisAdd BLAST1708

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini198 – 288CAInterPro annotationAdd BLAST91
Domaini309 – 403CAInterPro annotationAdd BLAST95
Domaini427 – 521CAInterPro annotationAdd BLAST95
Domaini545 – 626CAInterPro annotationAdd BLAST82
Domaini651 – 761CAInterPro annotationAdd BLAST111
Domaini787 – 885CAInterPro annotationAdd BLAST99
Domaini911 – 1006CAInterPro annotationAdd BLAST96
Domaini1030 – 1127CAInterPro annotationAdd BLAST98
Domaini1162 – 1248CAInterPro annotationAdd BLAST87
Domaini1272 – 1360CAInterPro annotationAdd BLAST89

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1709 – 1730DisorderedSequence analysisAdd BLAST22

Keywords - Domaini

RepeatARBA annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00028, Cadherin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205, CADHERIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112, CA, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313, SSF49313, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00232, CADHERIN_1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q19KJ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVDVRIFTA AVFILAAHFT FAQDCSYMVT IPRPERPDFP SQNFDGIPWS
60 70 80 90 100
QYPLIPVEGR EDVCMNEFQP GNQNPVTVIF MEEEIEGDVA IARLNYRGTN
110 120 130 140 150
TPTIVSPFSF GTFNMLGPVI RRIPENGGDW HLVITQRQDY ETPGMQQYIF
160 170 180 190 200
DVRVDDEPLV ATVMLLIVNI DDNDPIIQMF EPCDIPERGE TGITSCKYTV
210 220 230 240 250
SDADGEISTR FMRFEISSDR DDDEYFELVR ENIQGQWMYV HMRVHVKKPL
260 270 280 290 300
DYEENPLHLF RVTAYDSLPN THTVTMMVQV ENVENRPPRL GEIFAVQQFD
310 320 330 340 350
EKTERSFRVR AIDGDTGIDK PIFYRIETEK GEEDLFSIQT IEGGREGAWF
360 370 380 390 400
NVAPIDRDTL EKEVFHVSII ACKYGDNDVE GSSSFQSKTD VVIIVNDVND
410 420 430 440 450
QAPLPFREEY SIEIMEETAM TLNLEDFGFH DRDLGPHAQY TVHLESIHPP
460 470 480 490 500
RAHEAFYIAP EVGYQRQSFI MGTQNHHMLD FEVPEFQNIQ LRAIAIDMDD
510 520 530 540 550
PKWVGIAIIN IKLINWNDEL PMFESDVQTV SFDETEGAGF YVATVVAKDR
560 570 580 590 600
DVGDKVEHSL MGNAVSYLRM DKETGEIFVT ENEAFNYHRQ NELFVQIRAD
610 620 630 640 650
DTLGEPYNTN TTQLVIKLRD INNTPPTLRL PRSTPSVEEN VPDGFVIPTQ
660 670 680 690 700
LNATDPDTTA ELRFEIDWEN SYATKQGRNT DSKEYIGCIE IETIYPNINQ
710 720 730 740 750
RGNAIGRVVV REIRDGVTID YEMFEVLYLT VIVRDLNTVI GEDHDISTFT
760 770 780 790 800
ITIIDMNDNP PLWVEGTLTQ EFRVREVAAS GVVIGSVLAT DIDGPLYNQV
810 820 830 840 850
RYTITPRLDT PEDLVDIDFN TGQISVKLHQ AIDADEPPRQ NLYYTVIASD
860 870 880 890 900
KCDLHTVTEC PPDPTYFETP GEITIHITDT NNKVPQVEDD KFEAKVYIYE
910 920 930 940 950
GADDGEHVVQ IYASDLDRDE IYHKVSYQIN YAINSRLRDF FEMDLETGLV
960 970 980 990 1000
YVNNTAGELL DRDGDEPTHR IFFNVIDNFY GEGDGNRNQN ETQVLVVLLD
1010 1020 1030 1040 1050
INDNYPELPE TIPWAISESL EQGERVPPEI FARDRDEPGT DNSRVAYAIT
1060 1070 1080 1090 1100
GLTSTDRDIQ VPDLFNMITI ERDRGIDQTG ILEAAMDLRG YWGTYEIDIQ
1110 1120 1130 1140 1150
AYDHGIPQRI SNQKYPLVIR PYNFHDPVFV FPQPGSTIRL AKERAVVNGI
1160 1170 1180 1190 1200
LATVDGEFLD RIVATDEDGL EAGLVTFSIA GDDEDAQFFD VLNDGVNSGS
1210 1220 1230 1240 1250
LTLTRLFPED FREFQVTIRA TDGGTEPGPR STDCAVTVVF VPTQGEPVFE
1260 1270 1280 1290 1300
ESTYTVAFVE KDEGMEERAE LPRASDPRNI MCEDDCHDTY YSIVGGNSGE
1310 1320 1330 1340 1350
HFRVDPRTNV LTLAKPLDRS EQETHTLIIG ASDTPNPAAV LQASTLTVTV
1360 1370 1380 1390 1400
NVREANPRPV FQRALYTAGI SAGDFIERNL LTVVATHSEG LPITYTLIQE
1410 1420 1430 1440 1450
SMEADPPLEA VQESAFILNP ETGVLSLNFQ PTAAMHGMFE FEVEATDSRR
1460 1470 1480 1490 1500
ETARTEVKVY LISDRNRVFF TFNNPLPEVT PQEDFIAETF TAFFGMTCNI
1510 1520 1530 1540 1550
DQTWWASDPV TGATRDDQTE VRAHFIRDDL PVPAEEIEQL RGNPTLVNSI
1560 1570 1580 1590 1600
QRALEEQNLQ LADLFTGETP ILGGDAQARA LYALAAVAAA LALFVVVLLI
1610 1620 1630 1640 1650
VFFVRTRTLN RRLQALSMTK YSSQDSGLNR VGLAAPGTNK HAVEGSNPIW
1660 1670 1680 1690 1700
NETLKAPDFD ALSEQSYDSD LIGIEDLPQF RNDYFPPEEG SSMRGVVNEH
1710 1720 1730
VPESIANHNN NFGFNSTPFS PEFANTQFRR
Length:1,730
Mass (Da):195,317
Last modified:July 11, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i440BA66F3A14A7F8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ523166 Genomic DNA Translation: ABF69362.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ523166 Genomic DNA Translation: ABF69362.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
PfamiView protein in Pfam
PF00028, Cadherin, 1 hit
PRINTSiPR00205, CADHERIN
SMARTiView protein in SMART
SM00112, CA, 10 hits
SUPFAMiSSF49313, SSF49313, 11 hits
PROSITEiView protein in PROSITE
PS00232, CADHERIN_1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ19KJ3_HELAM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q19KJ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: August 12, 2020
This is version 58 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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