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Entry version 141 (16 Oct 2019)
Sequence version 4 (21 Sep 2011)
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Protein

Transcription enhancer factor-like protein egl-44

Gene

egl-44

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts upstream of egl-46 to prevent touch cell differentiation in FLP neurons (PubMed:11274062). Also promotes HSN neuron development (PubMed:11274062). In association with egl-46, regulates cell cycle exit in the neuronal Q cell lineage (PubMed:23946438). May be involved in thermal stress response downstream of yap-1 (PubMed:23396260).1 Publication2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi88 – 164TEAPROSITE-ProRule annotationAdd BLAST77

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processCell cycle, Differentiation, Neurogenesis, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription enhancer factor-like protein egl-44
Alternative name(s):
Egg-laying defective protein 44
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:egl-44
ORF Names:F28B12.2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
F28B12.2a ; CE44866 ; WBGene00001208 ; egl-44
F28B12.2b ; CE45037 ; WBGene00001208 ; egl-44
F28B12.2c ; CE44843 ; WBGene00001208 ; egl-44
F28B12.2d ; CE45004 ; WBGene00001208 ; egl-44
F28B12.2f ; CE44907 ; WBGene00001208 ; egl-44

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi91A → V in cas140; production of an extra neuron from the Q lineage and a mild egg-laying defect. 1 Publication1
Mutagenesisi134A → V in n1080 and cas58; two-fold reduction in mRNA levels. Production of an extra neuron from the Q lineage and a mild egg-laying defect. 2 Publications1
Mutagenesisi140R → Q in n998, n1087 and cas6; two-fold reduction in mRNA levels. Production of an extra neuron from the Q lineage and a mild egg-laying defect. 2 Publications1
Mutagenesisi145R → K in cas3; production of an extra neuron from the Q lineage and a mild egg-laying defect. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002059441 – 486Transcription enhancer factor-like protein egl-44Add BLAST486

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q19849

PeptideAtlas

More...
PeptideAtlasi
Q19849

PRoteomics IDEntifications database

More...
PRIDEi
Q19849

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in HSN neurons in embryos and in the FLP neurons from the L1 stage through to adults. Not expressed in touch cells. Also expressed in larval hypodermis, intestine, pharyngeal muscle and other neurons. In adults expression is lost from some neurons, is weaker in the hypodermis but remains in the intestine.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed from before gastrulation through to adult.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00001208 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q19849 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via N-terminus) with egl-46 (via C-terminus); the interaction is direct (PubMed:23946438).

Interacts with yap-1 (via WW domain); the interaction may regulate transcription (PubMed:23396260).

2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
39346, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q19849, 4 interactors

STRING: functional protein association networks

More...
STRINGi
6239.F28B12.2a

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q19849

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi170 – 196Pro-richAdd BLAST27

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3841 Eukaryota
ENOG410XQMP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182956

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q19849

Identification of Orthologs from Complete Genome Data

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OMAi
TSAEWVP

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.10.10.1610, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000818 TEA/ATTS_dom
IPR038096 TEA/ATTS_sf
IPR016361 TEF_metazoa
IPR041086 YBD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01285 TEA, 1 hit
PF17725 YBD, 1 hit

PIRSF; a whole-protein classification database

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PIRSFi
PIRSF002603 TEF, 1 hit

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00065 TEADOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00426 TEA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00554 TEA_1, 1 hit
PS51088 TEA_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 5 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform a (identifier: Q19849-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNSMFCSELQ QALPQMSEDV AVTAQTILNG TPPHNHFRKE WLAGAAGTTT
60 70 80 90 100
PTTTSGGQMM TLSPPAGDGP GSAGSMAPES TSSLSDLSGD AEGVWSIDID
110 120 130 140 150
QAFQEALAIY PPCGRRKIII SDEGKMYGRN ELIARYIKLR CGKTRTRKQV
160 170 180 190 200
SSHIQVLARK KLRDEQAKKK GDIPSLLQQA SPPGGVKSPS AVVFPPVSAA
210 220 230 240 250
VAAITEISPQ SSYSSIVPKV ETDQISQQLF KSLPLWSFQQ TPGLPIGMDL
260 270 280 290 300
SQLVFQQSSP DKTVSPVKSE VVEETKPIAS SQLTLHSFSA YVKCNKTSLR
310 320 330 340 350
TELVKIENTL EKDDIDISVF YEKYPKLLRE LFEKSEKKDV FFLAKCWANI
360 370 380 390 400
NVSDDVQNCQ YAVDSFYSSR EKFQLKVSTM ACSFGNQAVE KIEQYFPIEF
410 420 430 440 450
DGSYSFILNN SPMCDYMVKF IAELKKLNVI ETMNNVLENF TVLQIVTNSE
460 470 480
TDELLMVLCF VFEVSQEPEP SCSVYRLIDG GGDSDE
Length:486
Mass (Da):53,692
Last modified:September 21, 2011 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4584AA0B129FCA7A
GO
Isoform b (identifier: Q19849-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-15: Missing.
     170-170: K → KVPFHLNT

Note: No experimental confirmation available.
Show »
Length:478
Mass (Da):52,792
Checksum:iBEF240C22E01D32A
GO
Isoform c (identifier: Q19849-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-15: Missing.

Note: No experimental confirmation available.
Show »
Length:471
Mass (Da):51,983
Checksum:i6B32A90DF67C447D
GO
Isoform d (identifier: Q19849-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-75: Missing.

Note: No experimental confirmation available.
Show »
Length:411
Mass (Da):46,034
Checksum:i8E93596F5D16CA08
GO
Isoform f (identifier: Q19849-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-58: Missing.
     170-170: K → KVPFHLNT

Note: No experimental confirmation available.
Show »
Length:435
Mass (Da):48,357
Checksum:iE1E62F939460F539
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2C9C2P8A0A2C9C2P8_CAEEL
TEA domain-containing protein
egl-44 CELE_F28B12.2, F28B12.2
493Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2C9C3C4A0A2C9C3C4_CAEEL
TEA domain-containing protein
egl-44 CELE_F28B12.2, F28B12.2
485Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2C9C3H3A0A2C9C3H3_CAEEL
TEA domain-containing protein
egl-44 CELE_F28B12.2, F28B12.2
492Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2C9C333A0A2C9C333_CAEEL
TEA domain-containing protein
egl-44 CELE_F28B12.2, F28B12.2
428Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2C9C2W1A0A2C9C2W1_CAEEL
TEA domain-containing protein
egl-44 CELE_F28B12.2, F28B12.2
418Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG13397 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0418011 – 75Missing in isoform d. CuratedAdd BLAST75
Alternative sequenceiVSP_0418021 – 58Missing in isoform f. CuratedAdd BLAST58
Alternative sequenceiVSP_0418031 – 15Missing in isoform b and isoform c. CuratedAdd BLAST15
Alternative sequenceiVSP_041804170K → KVPFHLNT in isoform b and isoform f. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF283982 Genomic DNA Translation: AAG13397.1 Sequence problems.
FO080105 Genomic DNA Translation: CCD61238.1
FO080105 Genomic DNA Translation: CCD61239.1
FO080105 Genomic DNA Translation: CCD61240.1
FO080105 Genomic DNA Translation: CCD61241.1
FO080105 Genomic DNA Translation: CCD61242.1

NCBI Reference Sequences

More...
RefSeqi
NP_495186.3, NM_062785.3 [Q19849-3]
NP_741006.3, NM_171007.3 [Q19849-1]
NP_741007.2, NM_171850.4 [Q19849-2]
NP_871904.2, NM_182104.3 [Q19849-4]
NP_871906.2, NM_182106.4 [Q19849-6]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F28B12.2a.1; F28B12.2a.1; WBGene00001208 [Q19849-2]
F28B12.2b.1; F28B12.2b.1; WBGene00001208 [Q19849-1]
F28B12.2c.1; F28B12.2c.1; WBGene00001208 [Q19849-3]
F28B12.2d.1; F28B12.2d.1; WBGene00001208 [Q19849-4]
F28B12.2f.1; F28B12.2f.1; WBGene00001208 [Q19849-6]

Database of genes from NCBI RefSeq genomes

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GeneIDi
174005

UCSC genome browser

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UCSCi
F28B12.2a c. elegans [Q19849-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF283982 Genomic DNA Translation: AAG13397.1 Sequence problems.
FO080105 Genomic DNA Translation: CCD61238.1
FO080105 Genomic DNA Translation: CCD61239.1
FO080105 Genomic DNA Translation: CCD61240.1
FO080105 Genomic DNA Translation: CCD61241.1
FO080105 Genomic DNA Translation: CCD61242.1
RefSeqiNP_495186.3, NM_062785.3 [Q19849-3]
NP_741006.3, NM_171007.3 [Q19849-1]
NP_741007.2, NM_171850.4 [Q19849-2]
NP_871904.2, NM_182104.3 [Q19849-4]
NP_871906.2, NM_182106.4 [Q19849-6]

3D structure databases

SMRiQ19849
ModBaseiSearch...

Protein-protein interaction databases

BioGridi39346, 1 interactor
IntActiQ19849, 4 interactors
STRINGi6239.F28B12.2a

Proteomic databases

PaxDbiQ19849
PeptideAtlasiQ19849
PRIDEiQ19849

Genome annotation databases

EnsemblMetazoaiF28B12.2a.1; F28B12.2a.1; WBGene00001208 [Q19849-2]
F28B12.2b.1; F28B12.2b.1; WBGene00001208 [Q19849-1]
F28B12.2c.1; F28B12.2c.1; WBGene00001208 [Q19849-3]
F28B12.2d.1; F28B12.2d.1; WBGene00001208 [Q19849-4]
F28B12.2f.1; F28B12.2f.1; WBGene00001208 [Q19849-6]
GeneIDi174005
UCSCiF28B12.2a c. elegans [Q19849-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
174005
WormBaseiF28B12.2a ; CE44866 ; WBGene00001208 ; egl-44
F28B12.2b ; CE45037 ; WBGene00001208 ; egl-44
F28B12.2c ; CE44843 ; WBGene00001208 ; egl-44
F28B12.2d ; CE45004 ; WBGene00001208 ; egl-44
F28B12.2f ; CE44907 ; WBGene00001208 ; egl-44

Phylogenomic databases

eggNOGiKOG3841 Eukaryota
ENOG410XQMP LUCA
GeneTreeiENSGT00950000182956
InParanoidiQ19849
OMAiTSAEWVP

Enzyme and pathway databases

ReactomeiR-CEL-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression

Miscellaneous databases

Protein Ontology

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PROi
PR:Q19849

Gene expression databases

BgeeiWBGene00001208 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)
ExpressionAtlasiQ19849 baseline and differential

Family and domain databases

Gene3Di1.10.10.1610, 1 hit
InterProiView protein in InterPro
IPR000818 TEA/ATTS_dom
IPR038096 TEA/ATTS_sf
IPR016361 TEF_metazoa
IPR041086 YBD
PfamiView protein in Pfam
PF01285 TEA, 1 hit
PF17725 YBD, 1 hit
PIRSFiPIRSF002603 TEF, 1 hit
PRINTSiPR00065 TEADOMAIN
SMARTiView protein in SMART
SM00426 TEA, 1 hit
PROSITEiView protein in PROSITE
PS00554 TEA_1, 1 hit
PS51088 TEA_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEGL44_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q19849
Secondary accession number(s): D7SFJ5
, D7SFJ6, D7SFJ7, D7SFJ8, D7SFJ9, Q86NH3, Q86NH4, Q86NH5, Q86NH6, Q95QI4, Q9GT31
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: September 21, 2011
Last modified: October 16, 2019
This is version 141 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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