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Entry version 170 (02 Jun 2021)
Sequence version 3 (06 Feb 2007)
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Protein

Neurexin like receptor 1

Gene

nlr-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for gap junction formation, playing a role in anchoring the cytoskeletal component F-actin to the membrane of adjacent cells and thus facilitating the formation of gap junction channels in embryonic cells, muscle cells and neuronal cells (PubMed:33238150).

Plays a role in maintaining gap junction activity to promote pharyngeal muscle contraction (PubMed:33238150).

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: UniProtKB
  • calcium ion binding Source: InterPro
  • gap junction channel activity Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neurexin like receptor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nlr-1Imported
ORF Names:F20B10.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
F20B10.1 ; CE40647 ; WBGene00003772 ; nlr-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini21 – 1108ExtracellularCuratedAdd BLAST1088
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1109 – 1129HelicalSequence analysisAdd BLAST21
Topological domaini1130 – 1180CytoplasmicCuratedAdd BLAST51

Keywords - Cellular componenti

Cell junction, Cell membrane, Gap junction, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

RNAi-mediated knockdown results in abherrent inx-3-positive gap junction formation along the adjoining membranes of EA and EP endodermal precursor cells at the 16-24 cell stage of embryogenesis, and in adult pharyngeal muscles (PubMed:33238150). The inx-3-positive gap junctions are increased in number, are randomly positioned at irregular intervals on either the EA and EP cells and, although they are along the membrane, they are not on the membrane (PubMed:33238150). Furthermore, F-actin does not accumulate at the gap junction formation plaque in between the EA and EP adjoining membrane, but randomly forms patches along the membrane (PubMed:33238150). RNAi-mediated knockdown does not affect the expression of inx-3 (PubMed:33238150). RNAi-mediated knockdown impairs gap junction function in pharyngeal muscles which disrupts the synchronized muscle contraction between the pharyngeal metacorpus and terminal bulbs and thereby decreases the pharyngeal pumping rate (PubMed:33238150). RNAi-mediated knockdown in the nerve ring results in uncoordinated movements (also known as an unc phenotype), decreased locomotion and defective unc-9-positive gap junction formation and morphology (PubMed:33238150).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500418734921 – 1180Neurexin like receptor 1Sequence analysisAdd BLAST1160

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi229N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi267 ↔ 290PROSITE-ProRule annotation
Glycosylationi302N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi336N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi355N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi436N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi448 ↔ 459PROSITE-ProRule annotation
Disulfide bondi453 ↔ 469PROSITE-ProRule annotation
Disulfide bondi471 ↔ 480PROSITE-ProRule annotation
Glycosylationi522N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi636N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi863 ↔ 874PROSITE-ProRule annotation
Disulfide bondi868 ↔ 883PROSITE-ProRule annotation
Disulfide bondi885 ↔ 895PROSITE-ProRule annotation
Glycosylationi933N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi949N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi978N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi997N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1011N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1052N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q19617

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q19617

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in pharyngeal g1 and g2 gland cells, pharyngeal muscle cells and the unilateral GABAergic RIS interneuron (at protein level) (PubMed:21055481). Expressed in pm5 pharyngeal muscle cells and the nerve ring (PubMed:33238150).2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed during all stages of larval development and adulthood (at protein level) (PubMed:21055481). Expressed during embryogenesis (PubMed:33238150). Expressed in EA and EP endodermal precursor cells at the 16-24 cell stage of embryogenesis (PubMed:33238150).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00003772, Expressed in multi-cellular organism and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via the intracellular domain) with F-actin; the interaction is required for anchoring F-actin at the membrane for gap junction formation.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

Database of interacting proteins

More...
DIPi
DIP-26832N

STRING: functional protein association networks

More...
STRINGi
6239.F20B10.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini124 – 290Laminin G-like 1PROSITE-ProRule annotationAdd BLAST167
Domaini444 – 481EGF-like 1PROSITE-ProRule annotationAdd BLAST38
Domaini695 – 863Laminin G-like 2PROSITE-ProRule annotationAdd BLAST169
Domaini859 – 896EGF-like 2PROSITE-ProRule annotationAdd BLAST38

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1142 – 1180DisorderedSequence analysisAdd BLAST39

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the neurexin family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3516, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160532

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_273234_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q19617

Identification of Orthologs from Complete Genome Data

More...
OMAi
NERHSYW

Database of Orthologous Groups

More...
OrthoDBi
338397at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q19617

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR001791, Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00008, EGF, 1 hit
PF02210, Laminin_G_2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 2 hits
SM00179, EGF_CA, 2 hits
SM00282, LamG, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899, SSF49899, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010, ASX_HYDROXYL, 1 hit
PS00022, EGF_1, 1 hit
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 2 hits
PS50025, LAM_G_DOMAIN, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q19617-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGLCLVLLL SIFAVSQSSG ECSDVSFSSV ASKLDGLKRV TRLSVSGHIS
60 70 80 90 100
AYHVKVSISD DDFQLVRLSN GNPLVLYSTL SNTPSWTHVD FLATEVRIFP
110 120 130 140 150
AFEQATEDVR GPLLILTICD YDTPITAFDD SSYTVEAHHA GLVSMYENDL
160 170 180 190 200
CVVFRTYRSG VFFFSMADQG DVLIAQIIHG TVHVIFDFGS LTPSRISAGK
210 220 230 240 250
ALDDGRWHEM RWLHQFDSVQ LSIDGVLLNQ TAPTGLYRKL DLHSVVHIGG
260 270 280 290 300
RPNDDFSQGI ETTFTGCIAR LQLNNADLLQ LSPNEVHNQC QMPKPPSFTL
310 320 330 340 350
HNSSRAVLPF TFLPFSFEFR IVPINGPLVT LFDAENGTLV DVVIDEESKL
360 370 380 390 400
HLVSNITKFK QAANPAIDVA DGAWHSFSLR IRGVRMEIDI DGYTVLWLEG
410 420 430 440 450
HEVRRVSQRL SNFILSASGC YRSVTIDLTS VRVDGNVTRG ECTFQEKCLP
460 470 480 490 500
NPCENGGGCV QSALDDYVCN CKEGYKGKNC HTTDLPHSCE EWVFTKGNKQ
510 520 530 540 550
KAVQGRKVLI DIDGGGEMQP INVTCKTERD EIGIDGVSTI LEHDLLRPMI
560 570 580 590 600
VTGDNKPGAV RYSLTYGIST EQMDRLVEGF EACSQFMRYT CRGGARLMTQ
610 620 630 640 650
GDERSPSSWY STRSDKHGLQ WGEAPPYSRM CSCAINGSCL HNRMCNCDSG
660 670 680 690 700
EDSTDEGVNP YSQLLPVTGL FLGGTTKSSS IEVEIGPLKC RNRATFDPVT
710 720 730 740 750
FSNRNAKLSG AQTFNQRTFD VSLHVKFSHS QMSILSWHST DDLHWFHLYV
760 770 780 790 800
NDGKIVGEVV NGGESQQIVS EHRYDDGKFH AIYWEADSTG MFLKVDGQRK
810 820 830 840 850
SVKTSFILPT VYMWIVGSRT EKGSTGFAGV IRNVHLCGVE LALGQYARKE
860 870 880 890 900
TERGVAIGDD GYCRPDLCQN GGQCVDKYDG YVCDCSMTPF GGSDCTKEYG
910 920 930 940 950
MMVPAGSSIQ IPWQNPAHQA MCHRIAIQTT SRNTTILRSK ALFADSTFNM
960 970 980 990 1000
TVDDNGNLQM MAYDGFFFHF KRQSKRHNLS DDIMHDISFC ASKHHFNVSV
1010 1020 1030 1040 1050
DGMQVITIEG NWTFFESFNV WHFLDENFEG CVSRIQTGSA FPLKNPKTAR
1060 1070 1080 1090 1100
LNYSGKIRFG TCPIEAVSRQ QMYDFNPQPD LISSTIKTST EDIKIFSVSQ
1110 1120 1130 1140 1150
NKQDLVSKAI IGGGILALSL FILCMSSLIC YMRSRPEGVY KTNETGENCS
1160 1170 1180
PSRSEEPLVH NTTSNNNNNP TYASNKEYFC
Length:1,180
Mass (Da):131,154
Last modified:February 6, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAB91A1B71FE73E5B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAA93465.2

Protein sequence database of the Protein Information Resource

More...
PIRi
T21133

NCBI Reference Sequences

More...
RefSeqi
NP_502312.2, NM_069911.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F20B10.1.1; F20B10.1.1; WBGene00003772

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
178167

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F20B10.1

UCSC genome browser

More...
UCSCi
F20B10.1, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAA93465.2
PIRiT21133
RefSeqiNP_502312.2, NM_069911.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

DIPiDIP-26832N
STRINGi6239.F20B10.1

Proteomic databases

EPDiQ19617
PaxDbiQ19617

Genome annotation databases

EnsemblMetazoaiF20B10.1.1; F20B10.1.1; WBGene00003772
GeneIDi178167
KEGGicel:CELE_F20B10.1
UCSCiF20B10.1, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
178167
WormBaseiF20B10.1 ; CE40647 ; WBGene00003772 ; nlr-1

Phylogenomic databases

eggNOGiKOG3516, Eukaryota
GeneTreeiENSGT00940000160532
HOGENOMiCLU_273234_0_0_1
InParanoidiQ19617
OMAiNERHSYW
OrthoDBi338397at2759
PhylomeDBiQ19617

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q19617

Gene expression databases

BgeeiWBGene00003772, Expressed in multi-cellular organism and 5 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR000152, EGF-type_Asp/Asn_hydroxyl_site
IPR001791, Laminin_G
PfamiView protein in Pfam
PF00008, EGF, 1 hit
PF02210, Laminin_G_2, 2 hits
SMARTiView protein in SMART
SM00181, EGF, 2 hits
SM00179, EGF_CA, 2 hits
SM00282, LamG, 2 hits
SUPFAMiSSF49899, SSF49899, 4 hits
PROSITEiView protein in PROSITE
PS00010, ASX_HYDROXYL, 1 hit
PS00022, EGF_1, 1 hit
PS01186, EGF_2, 1 hit
PS50026, EGF_3, 2 hits
PS50025, LAM_G_DOMAIN, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNLR1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q19617
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 7, 2021
Last sequence update: February 6, 2007
Last modified: June 2, 2021
This is version 170 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
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