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Protein

Probable DNA polymerase delta small subunit

Gene

F12F6.7

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The function of the small subunit is not yet clear.

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-directed DNA polymerase, Nucleotidyltransferase, Transferase
Biological processDNA replication

Enzyme and pathway databases

ReactomeiR-CEL-69166 Removal of the Flap Intermediate
R-CEL-69183 Processive synthesis on the lagging strand

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA polymerase delta small subunit (EC:2.7.7.7)
Gene namesi
ORF Names:F12F6.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF12F6.7 ; CE05595 ; WBGene00008722

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000961691 – 451Probable DNA polymerase delta small subunitAdd BLAST451

Proteomic databases

EPDiQ19366
PaxDbiQ19366
PeptideAtlasiQ19366
PRIDEiQ19366

Expressioni

Gene expression databases

BgeeiWBGene00008722

Interactioni

Subunit structurei

Heterodimer with subunits of 125 kDa and 50 kDa.By similarity

Protein-protein interaction databases

IntActiQ19366, 1 interactor
STRINGi6239.F12F6.7.2

Structurei

3D structure databases

ProteinModelPortaliQ19366
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2732 Eukaryota
COG1311 LUCA
GeneTreeiENSGT00390000006780
HOGENOMiHOG000017939
InParanoidiQ19366
KOiK02328
OMAiTRLIQMR
OrthoDBiEOG091G094I
PhylomeDBiQ19366

Family and domain databases

InterProiView protein in InterPro
IPR007185 DNA_pol_alpha/epsilon_bsu
IPR024826 DNA_pol_delta/II_ssu
PANTHERiPTHR10416 PTHR10416, 1 hit
PfamiView protein in Pfam
PF04042 DNA_pol_E_B, 1 hit

Sequencei

Sequence statusi: Complete.

Q19366-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METAWSNILN YKNVSDRYIL TEKDKKGAFT RQYFEVYEAR LKELKPRILE
60 70 80 90 100
NAEREIGKGK FTHSQLSDAK QDEEIFVVGV IVKRIAARPS ILKSLLNEDK
110 120 130 140 150
VAYDDYEEDA EEDEVKRYAG SIEDRIELES DKQTVRLEGN ISMDECATGC
160 170 180 190 200
CVGVLGKLGK EGVFHVNRLV WPSVKVPKKV AVDGTIAFVS GLDLTGDLED
210 220 230 240 250
DRLTISGLEF MADWMNVQVG NENQCPPIDR LVVIGPLVET KSNGCDVQSV
260 270 280 290 300
VRTLTLSRAE KHSSTASLIT VDKIINSIAE KPLVNTVDVT PGVGDPCSSM
310 320 330 340 350
WPLPPIHRVC LPRCGMSDKK VNLVTNPYEF EVNGLRVMTM SGENVSELLR
360 370 380 390 400
TSLKWTGADA IENIIKWQHV APNCPDTLDA FPVAERDPLI MDITPHVIIC
410 420 430 440 450
GNQPHAEFRH IPIDGSNCLV VCLPKFSKTR VACFLNLSDL SLKWQNFDHQ

F
Length:451
Mass (Da):50,404
Last modified:November 1, 1996 - v1
Checksum:i6DCC014A809942C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73425 Genomic DNA Translation: CAA97785.1
PIRiT20798
RefSeqiNP_502177.1, NM_069776.4
UniGeneiCel.5571

Genome annotation databases

EnsemblMetazoaiF12F6.7.1; F12F6.7.1; WBGene00008722
F12F6.7.2; F12F6.7.2; WBGene00008722
GeneIDi178077
KEGGicel:CELE_F12F6.7
UCSCiF12F6.7.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiDPOD2_CAEEL
AccessioniPrimary (citable) accession number: Q19366
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health