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UniProtKB - Q19329 (TSR1_CAEEL)

Entry version 111 (23 Feb 2022)
Sequence version 1 (01 Nov 1996)
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Protein

Pre-rRNA-processing protein TSR1 homolog

Gene

tag-151

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required during maturation of the 40S ribosomal subunit in the nucleolus.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processRibosome biogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pre-rRNA-processing protein TSR1 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tag-151
ORF Names:F10G7.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...WormBasei		F10G7.1 ; CE02624 ; WBGene00006497 ; tag-151

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003112791 – 785Pre-rRNA-processing protein TSR1 homologAdd BLAST785

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q19329

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q19329

PeptideAtlas

More...PeptideAtlasi		Q19329

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		WBGene00006497, Expressed in multi-cellular organism and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		39166, 4 interactors

STRING: functional protein association networks

More...STRINGi		6239.F10G7.1.2

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q19329

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini83 – 243Bms1-type GPROSITE-ProRule annotationAdd BLAST161

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 59DisorderedSequence analysisAdd BLAST59
Regioni307 – 426DisorderedSequence analysisAdd BLAST120

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi24 – 59Basic and acidic residuesSequence analysisAdd BLAST36
Compositional biasi320 – 335Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi345 – 364Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi375 – 412Acidic residuesSequence analysisAdd BLAST38

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1980, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153195

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_009858_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q19329

Identification of Orthologs from Complete Genome Data

More...OMAi		CGYRRFV

Database of Orthologous Groups

More...OrthoDBi		186926at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q19329

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012948, AARP2CN
IPR039761, Bms1/Tsr1
IPR007034, BMS1_TSR1_C
IPR030387, G_Bms1/Tsr1_dom

The PANTHER Classification System

More...PANTHERi		PTHR12858, PTHR12858, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08142, AARP2CN, 1 hit
PF04950, RIBIOP_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00785, AARP2CN, 1 hit
SM01362, DUF663, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51714, G_BMS1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q19329-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTTGHRAGV FKKPSKPHKS WKGKRTKGEI TSENRGREGV KQLTRSAHST 
        60         70         80         90        100
HRTISKDARR NQLKMARDQK MADAMERRRT SNAPCLVTVV SLGVGARPTE 
       110        120        130        140        150
FIKKLATCDE TIIQTTSPST IDFAIPRFKS RVSFLTPDKD NVDGVLDAIR 
       160        170        180        190        200
ASDVLCFLWP MSAELSEWDE QLLTIIKANG LPTIVSVVPG LGSIANHKKK 
       210        220        230        240        250
EDVRKGIEFI ISKWSMSNAG VMPADSVTDN LQLLRILNET KKKPLTLQAR 
       260        270        280        290        300
HSYMLVENLE CSDKTGETCT LVAQGYLRGP EWNANNLVHL PGFGDFQISK 
       310        320        330        340        350
IESTVDPHPL KAHNKTPEAQ IIAKSDDKRQ NTETEITPDS MDGEQTWPTR 
       360        370        380        390        400
EELEEADKEL RRVPKGTSSY QAAWILDDED DEDEEDSDED MDDSDNEEVE 
       410        420        430        440        450
DDSEEEEPMD DLKSEAGETT ASEMMFDDGI DEDINMAEVE KYRKERENAQ 
       460        470        480        490        500
WPDEVDTPMD MPARIAFQKY RGLKSFRTST WDPKENLPLD YARIFQFANY 
       510        520        530        540        550
RNTKKNVMSK IGGNDVDADS VADKKFNGAF ASVFIENVPV AVLEAYKDAK 
       560        570        580        590        600
NLVLFQLLPH EHKMSVLNMV LKKHPSCTIP ITSDQNQKFI FYVGFRQFEA 
       610        620        630        640        650
NAVFSSNTPG DKFKLERFMP TEKTFVATVY APITFNPATV LCFRQDDKGR 
       660        670        680        690        700
QELVATGSIL DSNPDRIVLK RTVLAGHPYK INRRAVVVRY MFFNREDIEW 
       710        720        730        740        750
FKPVELYTPS GRRGHIKEAV GTHGNMKCRF DQQLNAQDSV MLNLYKRVFP 
       760        770        780 
VWNYSIFNRS LNPSRFVERS RVESISLVNE DAMEE
Length:785
Mass (Da):89,221
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1D40D32ED1263A45
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
FO081114 Genomic DNA Translation: CCD69203.1

Protein sequence database of the Protein Information Resource

More...PIRi		C88131

NCBI Reference Sequences

More...RefSeqi		NP_494840.1, NM_062439.6

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		F10G7.1.1; F10G7.1.1; WBGene00006497
F10G7.1.2; F10G7.1.2; WBGene00006497

Database of genes from NCBI RefSeq genomes

More...GeneIDi		173812

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		cel:CELE_F10G7.1

UCSC genome browser

More...UCSCi		F10G7.1.2, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081114 Genomic DNA Translation: CCD69203.1
PIRiC88131
RefSeqiNP_494840.1, NM_062439.6

3D structure databases

SMRiQ19329
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi39166, 4 interactors
STRINGi6239.F10G7.1.2

Proteomic databases

EPDiQ19329
PaxDbiQ19329
PeptideAtlasiQ19329

Genome annotation databases

EnsemblMetazoaiF10G7.1.1; F10G7.1.1; WBGene00006497
F10G7.1.2; F10G7.1.2; WBGene00006497
GeneIDi173812
KEGGicel:CELE_F10G7.1
UCSCiF10G7.1.2, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		173812
WormBaseiF10G7.1 ; CE02624 ; WBGene00006497 ; tag-151

Phylogenomic databases

eggNOGiKOG1980, Eukaryota
GeneTreeiENSGT00940000153195
HOGENOMiCLU_009858_1_0_1
InParanoidiQ19329
OMAiCGYRRFV
OrthoDBi186926at2759
PhylomeDBiQ19329

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q19329

Gene expression databases

BgeeiWBGene00006497, Expressed in multi-cellular organism and 5 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR012948, AARP2CN
IPR039761, Bms1/Tsr1
IPR007034, BMS1_TSR1_C
IPR030387, G_Bms1/Tsr1_dom
PANTHERiPTHR12858, PTHR12858, 1 hit
PfamiView protein in Pfam
PF08142, AARP2CN, 1 hit
PF04950, RIBIOP_C, 1 hit
SMARTiView protein in SMART
SM00785, AARP2CN, 1 hit
SM01362, DUF663, 1 hit
PROSITEiView protein in PROSITE
PS51714, G_BMS1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTSR1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q19329
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: November 1, 1996
Last modified: February 23, 2022
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families
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