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Protein
Submitted name:

Proteasome Regulatory Particle, Non-ATPase-like

Gene

rpn-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CEL-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
R-CEL-1236978 Cross-presentation of soluble exogenous antigens (endosomes)
R-CEL-174113 SCF-beta-TrCP mediated degradation of Emi1
R-CEL-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA
R-CEL-4608870 Asymmetric localization of PCP proteins
R-CEL-5632684 Hedgehog 'on' state
R-CEL-5668541 TNFR2 non-canonical NF-kB pathway
R-CEL-5689603 UCH proteinases
R-CEL-5689880 Ub-specific processing proteases
R-CEL-6798695 Neutrophil degranulation
R-CEL-68949 Orc1 removal from chromatin
R-CEL-69229 Ubiquitin-dependent degradation of Cyclin D1
R-CEL-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
R-CEL-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-CEL-8939902 Regulation of RUNX2 expression and activity
R-CEL-8941858 Regulation of RUNX3 expression and activity
R-CEL-8948751 Regulation of PTEN stability and activity
R-CEL-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Submitted name:
Proteasome Regulatory Particle, Non-ATPase-likeImported
Gene namesi
Name:rpn-5Imported
ORF Names:CELE_F10G7.8Imported, F10G7.8Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF10G7.8 ; CE02632 ; WBGene00004461 ; rpn-5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiQ19324
PaxDbiQ19324
PeptideAtlasiQ19324

Expressioni

Gene expression databases

BgeeiWBGene00004461

Interactioni

Protein-protein interaction databases

STRINGi6239.F10G7.8.3

Structurei

3D structure databases

ProteinModelPortaliQ19324
SMRiQ19324
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini267 – 446PCIInterPro annotationAdd BLAST180

Phylogenomic databases

eggNOGiKOG1498 Eukaryota
COG5071 LUCA
GeneTreeiENSGT00730000111110
HOGENOMiHOG000194265
InParanoidiQ19324
KOiK03035
OMAiKQAITKM
OrthoDBiEOG091G06CB
PhylomeDBiQ19324

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000717 PCI_dom
IPR035297 PSMD12
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR10855:SF1 PTHR10855:SF1, 1 hit
PfamiView protein in Pfam
PF01399 PCI, 1 hit
SMARTiView protein in SMART
SM00088 PINT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit

Sequencei

Sequence statusi: Complete.

Q19324-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADRREPIPV DPVDVGELSE LDNLAHLAAH GGDGRLFKME QDYSKQVDEA
60 70 80 90 100
LLKARDIAQK DAVAAVESLN NIEKLTRLGA DMKSNTRVVQ YMTKLCFEGQ
110 120 130 140 150
KWDLLMETIM TLSKKRLLIK MAIAKMVRDA VAMIDKMPTE DLKMKLIETL
160 170 180 190 200
RTVTAGKIYV EVERARLTSM VVKKLEREGK LDEAATMLLE LQVETYGSME
210 220 230 240 250
MREKVQYLLE QMRYSLVRND FVRATIISKK INIKFFNKSD EDEVQNLKLK
260 270 280 290 300
YYDSMIRIGL HDGNYLDVCR HHREIYETKK IKADSAKATS HLRSAIVYCL
310 320 330 340 350
LAPHTNEQWD LLNRIAIQRE LETVPDYKII LDLFINQELI SFKGTIVAKY
360 370 380 390 400
EKLLRRGTTS SPDTGIFDKS TEGEKRWSDL HLRVGEHNMR MIAKYYTQIT
410 420 430 440 450
FERLAELLDF PVDEMESFVC NLIVTGQITG AKLHRPSRIV NLRLKKANVE
460 470 480 490
QLDVWASNVH KLTDTLNKVS HLILKEQMVH KNLDLAAPRA
Length:490
Mass (Da):56,457
Last modified:November 1, 1996 - v1
Checksum:i93F456ACEE888949
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CCD69211.1
PIRiF88130
RefSeqiNP_494835.1, NM_062434.3
UniGeneiCel.6606

Genome annotation databases

EnsemblMetazoaiF10G7.8.1; F10G7.8.1; WBGene00004461
F10G7.8.2; F10G7.8.2; WBGene00004461
GeneIDi173807
KEGGicel:CELE_F10G7.8
UCSCiF10G7.8.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ19324_CAEEL
AccessioniPrimary (citable) accession number: Q19324
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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