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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Enzyme and pathway databases

BioCyciHWAL362976:G1G1J-2783-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:HQ_3686A
OrganismiHaloquadratum walsbyi (strain DSM 16790 / HBSQ001)
Taxonomic identifieri362976 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHaloferacalesHaloferacaceaeHaloquadratum
Proteomesi
  • UP000001975 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000191681 – 247DNA polymerase sliding clampAdd BLAST247

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi362976.HQ3686A

Structurei

3D structure databases

ProteinModelPortaliQ18E60
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OMAiSDGFDKY
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN

Sequencei

Sequence statusi: Complete.

Q18E60-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKAIVGAST LQDALDSVSV LVDECKIRLN EGELAIRAVD PANVGMVDLA
60 70 80 90 100
LDTAAFESYT ADDGVIGVNL SKLEDFIGMA SGDQLVELEL DEETRKLNIQ
110 120 130 140 150
MDGLSSTLAL IDPDSIRQEP DIPDLDLAAE IMLEGAQLDR GIKAADMVSD
160 170 180 190 200
HVRLRVASDT EAYHIEAEGD TDDVDFRLDT DDLIALTAGE ADSLFSLDYL
210 220 230 240
KDMNKAIPKD AEVTIELGQE FPVKVHYGIA EGYGEITYML APRIQSD
Length:247
Mass (Da):26,827
Last modified:July 25, 2006 - v1
Checksum:i7B718EC3551ECA53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM180088 Genomic DNA Translation: CAJ53773.1
RefSeqiWP_011572855.1, NC_008212.1

Genome annotation databases

EnsemblBacteriaiCAJ53773; CAJ53773; HQ_3686A
GeneIDi4194411
KEGGihwa:HQ_3686A

Similar proteinsi

Entry informationi

Entry nameiPCNA_HALWD
AccessioniPrimary (citable) accession number: Q18E60
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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