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Entry version 150 (02 Jun 2021)
Sequence version 3 (16 Jun 2009)
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Protein
Submitted name:

Uncharacterized protein

Gene

C46A5.4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

PeroxiBase, a peroxidase database

More...
PeroxiBasei
4143, CelPxt01

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:C46A5.4Imported, CELE_C46A5.4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
C46A5.4 ; CE43668 ; WBGene00016700

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500418686218 – 1537Sequence analysisAdd BLAST1520

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q18647

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q18647

PeptideAtlas

More...
PeptideAtlasi
Q18647

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00016700, Expressed in multi-cellular organism and 4 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.C46A5.4

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q18647

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2408, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166558

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005243_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q18647

Identification of Orthologs from Complete Genome Data

More...
OMAi
VCKVQCA

Database of Orthologous Groups

More...
OrthoDBi
276568at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q18647

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.640.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019791, Haem_peroxidase_animal
IPR010255, Haem_peroxidase_sf
IPR037120, Haem_peroxidase_sf_animal

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03098, An_peroxidase, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00457, ANPEROXIDASE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48113, SSF48113, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50292, PEROXIDASE_3, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q18647-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRKRLLFLLI LFSTCSASPF PCGPSFVPCT QKRAFSSLIH SPNKQFNKEF
60 70 80 90 100
GVEFGKHFDS EPSEKVKNEF KKSMKQEIIT TAASSAVRLT EKLFNDTEKL
110 120 130 140 150
MSDKFDDSFK QSELAWLHYT YADQYAKYLS FSAISSTLAS QMISEKSPKT
160 170 180 190 200
LKSMIQFLPT ENTKMKEICP VNQIEECVIG KYRSYTGHCN NVKNPLNGAS
210 220 230 240 250
YERLKRFLPA DYSDGISAPR SSKSGQPLPS SRALSALFTP SPSGHATCSL
260 270 280 290 300
LIAPFLSFIY DDIVHVPSNR IFKRDFYGND KAMPLPCCRG DNSHPECFEI
310 320 330 340 350
PVPEDDTLQS KNVKCLPYSR SLPVPNPKCS FGQRQQANMV TSYLDLSQIY
360 370 380 390 400
GSTEGIVKKM RLHKNGKLAL RAVGGFNNQL GVPPANLDSS ICRSSTGKPC
410 420 430 440 450
LLAGNNKINF LPTSGAIYTI WMRQHNVIAD KLASVNPHWD DQKVFEEARR
460 470 480 490 500
ITIAQFQHIT FNEMVPVLVG KEQLRVMGIK LQKNGYDSGY DINIDSSASN
510 520 530 540 550
VFASAAGQFF LTLLPSQFNI EDKRFSTKSE SLLKHFNDPA LIYEKGRIDG
560 570 580 590 600
MLKFLLNAPI EKPGLHSSPL LRTAFQKKDI ADSVDIIAMV IQMGRDHGLP
610 620 630 640 650
SYLQWRTFCK LDDFSSFLAL QTIFKPSVNI SDFERLYESP EDIDVFVGGL
660 670 680 690 700
SEQPTKGSLL GPTFACLFAH QMAQTKRGDR FWYENFVSPS AFTVDQIDEI
710 720 730 740 750
RKTTMARIIC DNTDTVTHVQ HHAFSLPDDY GNCPLSCNST GIIQVFDPKA
760 770 780 790 800
FKDEEKLTSL PITKETVEKV IRLGLRQWQR YEEGEGRRIS AQLSDSSPSA
810 820 830 840 850
LLSHALLMAP KKESIDIART ASVLREATNI LISGNGLDKD ERLPDLDIGT
860 870 880 890 900
LQKILPQIDV GSVIGNFTPF LARDPLPKEQ CLPEPLPCDH TSKYRTYSGW
910 920 930 940 950
CNNLKNPKFG NAFTQMRRLL DPAYDDGFDT PRTRSVLGSE LPSARKISNI
960 970 980 990 1000
VHSDAPKFHV KFTHMLMQFG QILDHDMMHS PISRGPKNTI LNCSSCDSAQ
1010 1020 1030 1040 1050
TLSIHCFPIK IEANDPFFPS KHSDGRPRCM PFARSLLAQV SLGFRNQLNQ
1060 1070 1080 1090 1100
LTSFLDASTI YGSTQCEANK LRLFSDGKLN FTDLGFNKEA LPQGNQERDC
1110 1120 1130 1140 1150
RSVLQNRQRR CFVAGDERSN EQPGLTAIHN IFLREHNRIA RYLKQINNFW
1160 1170 1180 1190 1200
SDEKLFQESR RINIAQLQHI IYKEWLPVVL GCQNMEKWGL MPQTAGYFEG
1210 1220 1230 1240 1250
YDDQCDATIS QEMSTSAFRF GHSLIRGVFT RMNDNFQNMT NHVNLTETFS
1260 1270 1280 1290 1300
NPSPVYDKNS GHMESILMGL IGANSMAFDR HIVTAVRNHL FAKPGGPLTG
1310 1320 1330 1340 1350
LDLPAVNIQR GRDHGVQGYN AYRKHCGLRK ASAFSDLRDV MNSEAVTALE
1360 1370 1380 1390 1400
TAYAHVDDID LFPGIMSESP TRGSLVGPTL ACLIGEQMQR LKKCDRFYYE
1410 1420 1430 1440 1450
TSDSMVRFTP DQLVEIRKAS LSRIICDNSE YAANIQPNVF LMPDDLTNSP
1460 1470 1480 1490 1500
MTCSELSEID LNKWVERDYC LVDERVVNRG KTKRITPCIT CTCTLEGPEC
1510 1520 1530
HSITIDDCSR LLRDYSITDI QKDPVCLIQC SQQLKKL
Length:1,537
Mass (Da):173,035
Last modified:June 16, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i14EDB94C26C81A8C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD66594.1

NCBI Reference Sequences

More...
RefSeqi
NP_501272.2, NM_068871.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C46A5.4.1; C46A5.4.1; WBGene00016700

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
177558

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C46A5.4

UCSC genome browser

More...
UCSCi
C46A5.4, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD66594.1
RefSeqiNP_501272.2, NM_068871.3

3D structure databases

SMRiQ18647
ModBaseiSearch...

Protein-protein interaction databases

STRINGi6239.C46A5.4

Protein family/group databases

PeroxiBasei4143, CelPxt01

Proteomic databases

EPDiQ18647
PaxDbiQ18647
PeptideAtlasiQ18647

Genome annotation databases

EnsemblMetazoaiC46A5.4.1; C46A5.4.1; WBGene00016700
GeneIDi177558
KEGGicel:CELE_C46A5.4
UCSCiC46A5.4, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
177558
WormBaseiC46A5.4 ; CE43668 ; WBGene00016700

Phylogenomic databases

eggNOGiKOG2408, Eukaryota
GeneTreeiENSGT00940000166558
HOGENOMiCLU_005243_0_0_1
InParanoidiQ18647
OMAiVCKVQCA
OrthoDBi276568at2759
PhylomeDBiQ18647

Gene expression databases

BgeeiWBGene00016700, Expressed in multi-cellular organism and 4 other tissues

Family and domain databases

Gene3Di1.10.640.10, 2 hits
InterProiView protein in InterPro
IPR019791, Haem_peroxidase_animal
IPR010255, Haem_peroxidase_sf
IPR037120, Haem_peroxidase_sf_animal
PfamiView protein in Pfam
PF03098, An_peroxidase, 2 hits
PRINTSiPR00457, ANPEROXIDASE
SUPFAMiSSF48113, SSF48113, 2 hits
PROSITEiView protein in PROSITE
PS50292, PEROXIDASE_3, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ18647_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q18647
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: June 16, 2009
Last modified: June 2, 2021
This is version 150 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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