UniProtKB - Q17WY3 (AMIF_HELAH)
Protein
Formamidase
Gene
amiF
Organism
Helicobacter acinonychis (strain Sheeba)
Status
Functioni
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.UniRule annotation
Catalytic activityi
- EC:3.5.1.49UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 60 | Proton acceptorUniRule annotation | 1 | |
Active sitei | 133 | Proton donorUniRule annotation | 1 | |
Active sitei | 166 | NucleophileUniRule annotation | 1 |
GO - Molecular functioni
- formamidase activity Source: UniProtKB-UniRule
GO - Biological processi
- nitrogen compound metabolic process Source: InterPro
Keywordsi
Molecular function | Hydrolase |
Enzyme and pathway databases
BioCyci | HACI382638:HAC_RS04625-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: FormamidaseUniRule annotation (EC:3.5.1.49UniRule annotation)Alternative name(s): Formamide amidohydrolaseUniRule annotation |
Gene namesi | Name:amiFUniRule annotation Ordered Locus Names:Hac_1079 |
Organismi | Helicobacter acinonychis (strain Sheeba) |
Taxonomic identifieri | 382638 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000067060 | 1 – 334 | FormamidaseAdd BLAST | 334 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 14 – 260 | CN hydrolasePROSITE-ProRule annotationAdd BLAST | 247 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG4105DCY Bacteria COG0388 LUCA |
HOGENOMi | HOG000077502 |
KOi | K01455 |
OMAi | RIWGCFS |
OrthoDBi | 1650683at2 |
Family and domain databases
Gene3Di | 3.60.110.10, 1 hit |
HAMAPi | MF_01243 Formamidase, 1 hit |
InterProi | View protein in InterPro IPR003010 C-N_Hydrolase IPR036526 C-N_Hydrolase_sf IPR022843 Formamidase |
Pfami | View protein in Pfam PF00795 CN_hydrolase, 1 hit |
SUPFAMi | SSF56317 SSF56317, 1 hit |
PROSITEi | View protein in PROSITE PS50263 CN_HYDROLASE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q17WY3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSIGSIGKP IEGFLVAAIQ FPVPIVNSKK DIENNVQSII RTLHATKAGY
60 70 80 90 100
PGVELIIFPE YSTQGLNTAK WLSEEFLLDV GGKETEAYAQ ACKEAKVYGV
110 120 130 140 150
FSIMERNPDP NKNPYNTAII INPKGEIILH YRKLFPWNPI EPWYPGDKGM
160 170 180 190 200
PVCDGPGGSK LAVCICHDGM IPELAREAAY KGCNVYIRIS GYSTQVNDQW
210 220 230 240 250
ILTNRSNAWH NLMYTVSVNL AGYDNVFYYF GEGQICNFDG TTLVQGHRNP
260 270 280 290 300
WEIVTGEIYP KMADNARLSW GLENNIYNLG HRGYVAKPGG EPDAGLTYIK
310 320 330
DLAASKYKLP WEDHMQIKDG SIYGYPTSGG RFGK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM260522 Genomic DNA Translation: CAJ99843.1 |
RefSeqi | WP_011577952.1, NC_008229.1 |
Genome annotation databases
EnsemblBacteriai | CAJ99843; CAJ99843; Hac_1079 |
KEGGi | hac:Hac_1079 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM260522 Genomic DNA Translation: CAJ99843.1 |
RefSeqi | WP_011577952.1, NC_008229.1 |
3D structure databases
SMRi | Q17WY3 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 382638.Hac_1079 |
Genome annotation databases
EnsemblBacteriai | CAJ99843; CAJ99843; Hac_1079 |
KEGGi | hac:Hac_1079 |
Phylogenomic databases
eggNOGi | ENOG4105DCY Bacteria COG0388 LUCA |
HOGENOMi | HOG000077502 |
KOi | K01455 |
OMAi | RIWGCFS |
OrthoDBi | 1650683at2 |
Enzyme and pathway databases
BioCyci | HACI382638:HAC_RS04625-MONOMER |
Family and domain databases
Gene3Di | 3.60.110.10, 1 hit |
HAMAPi | MF_01243 Formamidase, 1 hit |
InterProi | View protein in InterPro IPR003010 C-N_Hydrolase IPR036526 C-N_Hydrolase_sf IPR022843 Formamidase |
Pfami | View protein in Pfam PF00795 CN_hydrolase, 1 hit |
SUPFAMi | SSF56317 SSF56317, 1 hit |
PROSITEi | View protein in PROSITE PS50263 CN_HYDROLASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AMIF_HELAH | |
Accessioni | Q17WY3Primary (citable) accession number: Q17WY3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 5, 2008 |
Last sequence update: | July 25, 2006 | |
Last modified: | October 16, 2019 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteomeDocuments
- SIMILARITY comments
Index of protein domains and families