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Protein

Synaptotagmin-16

Gene

SYT16

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca2+-independent.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Synaptotagmin-16
Alternative name(s):
Chr14Syt
Synaptotagmin 14-like protein
Synaptotagmin XIV-related protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SYT16
Synonyms:STREP14, SYT14L, SYT14R
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000139973.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23142 SYT16

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610950 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q17RD7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
83851

Open Targets

More...
OpenTargetsi
ENSG00000139973

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134964250

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SYT16

Domain mapping of disease mutations (DMDM)

More...
DMDMi
313104017

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002585841 – 645Synaptotagmin-16Add BLAST645

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q17RD7

PeptideAtlas

More...
PeptideAtlasi
Q17RD7

PRoteomics IDEntifications database

More...
PRIDEi
Q17RD7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
61148
61149 [Q17RD7-2]
61150 [Q17RD7-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q17RD7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q17RD7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000139973 Expressed in 82 organ(s), highest expression level in middle temporal gyrus

CleanEx database of gene expression profiles

More...
CleanExi
HS_SYT14L
HS_SYT16

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q17RD7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q17RD7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA004199
HPA076871

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer. Can also form heterodimers (By similarity).By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123767, 18 interactors

Protein interaction database and analysis system

More...
IntActi
Q17RD7, 27 interactors

Molecular INTeraction database

More...
MINTi
Q17RD7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000394700

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q17RD7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q17RD7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini352 – 453C2 1PROSITE-ProRule annotationAdd BLAST102
Domaini507 – 611C2 2PROSITE-ProRule annotationAdd BLAST105

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the synaptotagmin family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1028 Eukaryota
ENOG410XT5D LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159673

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000070178

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG062897

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q17RD7

KEGG Orthology (KO)

More...
KOi
K19328

Identification of Orthologs from Complete Genome Data

More...
OMAi
EQDNDWS

Database of Orthologous Groups

More...
OrthoDBi
EOG091G099X

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q17RD7

TreeFam database of animal gene trees

More...
TreeFami
TF351132

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR028690 SYT16

The PANTHER Classification System

More...
PANTHERi
PTHR10024:SF113 PTHR10024:SF113, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168 C2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239 C2, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004 C2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q17RD7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVLAMASQDV QNFFQPFSSW ISRVYEALQQ AGDMLSASLV NISKQDSKLS
60 70 80 90 100
DKLDQDLDNI QIQETYFEDE EQDNDWSQED ANSLFLEVDH FSCCNSDLQD
110 120 130 140 150
SAQNSSPSLS QHAKDSCSTM SQWPNWASDD RKLPHVLSSI AEEEHHLEKQ
160 170 180 190 200
RSGLQHGFDS QLPGTLETVN GKKQVNSFGD DEELSTSSDS DEEVIKQFEI
210 220 230 240 250
SVSRSQSFRS VTSEKGKQTG LEQKPKFSRS LLTHGEDGTE VSACEDLDGA
260 270 280 290 300
SQRRYSENLS YGEDDHIPAH SQSPCERGDA KHHGTSHQES SVVQSLRRQS
310 320 330 340 350
TEGSLEMETA FNSRGFEDSY ATDSSSMWSP EEQDRTNLQV PSGVSEPISK
360 370 380 390 400
CGDLDVIFEY RAASQKLTVT IVRAQGLPDK DRSGVNSWQV HVVLLPGKKH
410 420 430 440 450
RGRTNIQRGP NPVFREKVTF AKLEPRDVAA CAVRFRLYAA RKMTRERMMG
460 470 480 490 500
EKLFYLSHLH PEGEMKVTLV LEPRSNISSG GSPLSPSAVS HSDSTSSTQS
510 520 530 540 550
LSHGGAPELL VGLSYNATTG RLSVEMIKGS HFRNLAVNRA PDTYGKLFLL
560 570 580 590 600
NSVGQEMSRC KTSIRRGQPN PVYKETFVFQ VALFQLSDVT LMISVYNRRT
610 620 630 640
MKRKEMIGWI ALGQNSSGEE EQDHWEEMKE TKGQQICRWH TLLES
Length:645
Mass (Da):72,274
Last modified:November 30, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA9E11164542AAAAE
GO
Isoform 2 (identifier: Q17RD7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     312-331: Missing.

Show »
Length:625
Mass (Da):70,039
Checksum:iA0C5FF2E7231293B
GO
Isoform 3 (identifier: Q17RD7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-442: Missing.

Note: No experimental confirmation available.
Show »
Length:203
Mass (Da):22,824
Checksum:iAC3B6BEE011868ED
GO
Isoform 4 (identifier: Q17RD7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     332-383: EQDRTNLQVP...AQGLPDKDRS → ANLNLKRKGY...SQSPSQSVVT
     384-645: Missing.

Note: No experimental confirmation available.
Show »
Length:383
Mass (Da):42,800
Checksum:iD2DC06B06EE32A84
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GUW0A0A1B0GUW0_HUMAN
Synaptotagmin-16
SYT16
221Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAE85114 differs from that shown. Reason: Erroneous termination at position 72. Translated as Gln.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti175V → I in BAC76810 (PubMed:12801916).Curated1
Sequence conflicti517A → V in CAE85114 (PubMed:15238157).Curated1
Sequence conflicti614Q → L in CAE85114 (PubMed:15238157).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02893010V → A1 PublicationCorresponds to variant dbSNP:rs8019076Ensembl.1
Natural variantiVAR_028931131R → L1 PublicationCorresponds to variant dbSNP:rs17099370Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0213781 – 442Missing in isoform 3. 1 PublicationAdd BLAST442
Alternative sequenceiVSP_021379312 – 331Missing in isoform 2. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_057225332 – 383EQDRT…DKDRS → ANLNLKRKGYLLDVYCLSSP LLFTTSLHRRNRTGPICRCH PGSQSPSQSVVT in isoform 4. 1 PublicationAdd BLAST52
Alternative sequenceiVSP_057226384 – 645Missing in isoform 4. 1 PublicationAdd BLAST262

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB102949 mRNA Translation: BAC76810.1
AJ617628 mRNA Translation: CAE85114.1 Sequence problems.
AK302919 mRNA Translation: BAG64084.1
AL356018 Genomic DNA No translation available.
AL390816 Genomic DNA No translation available.
BC040924 mRNA Translation: AAH40924.1
BC117363 mRNA Translation: AAI17364.1
BC143598 mRNA Translation: AAI43599.1
AJ303367 mRNA Translation: CAC33889.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS45121.1 [Q17RD7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_114120.2, NM_031914.2 [Q17RD7-1]
XP_006720335.1, XM_006720272.3 [Q17RD7-1]
XP_011535521.1, XM_011537219.1
XP_016877182.1, XM_017021693.1
XP_016877183.1, XM_017021694.1
XP_016877184.1, XM_017021695.1 [Q17RD7-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.404139
Hs.713240

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000430451; ENSP00000394700; ENSG00000139973 [Q17RD7-3]
ENST00000555409; ENSP00000451035; ENSG00000139973 [Q17RD7-4]
ENST00000568344; ENSP00000478637; ENSG00000139973 [Q17RD7-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
83851

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:83851

UCSC genome browser

More...
UCSCi
uc001xfu.2 human [Q17RD7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB102949 mRNA Translation: BAC76810.1
AJ617628 mRNA Translation: CAE85114.1 Sequence problems.
AK302919 mRNA Translation: BAG64084.1
AL356018 Genomic DNA No translation available.
AL390816 Genomic DNA No translation available.
BC040924 mRNA Translation: AAH40924.1
BC117363 mRNA Translation: AAI17364.1
BC143598 mRNA Translation: AAI43599.1
AJ303367 mRNA Translation: CAC33889.1
CCDSiCCDS45121.1 [Q17RD7-1]
RefSeqiNP_114120.2, NM_031914.2 [Q17RD7-1]
XP_006720335.1, XM_006720272.3 [Q17RD7-1]
XP_011535521.1, XM_011537219.1
XP_016877182.1, XM_017021693.1
XP_016877183.1, XM_017021694.1
XP_016877184.1, XM_017021695.1 [Q17RD7-1]
UniGeneiHs.404139
Hs.713240

3D structure databases

ProteinModelPortaliQ17RD7
SMRiQ17RD7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123767, 18 interactors
IntActiQ17RD7, 27 interactors
MINTiQ17RD7
STRINGi9606.ENSP00000394700

PTM databases

iPTMnetiQ17RD7
PhosphoSitePlusiQ17RD7

Polymorphism and mutation databases

BioMutaiSYT16
DMDMi313104017

Proteomic databases

PaxDbiQ17RD7
PeptideAtlasiQ17RD7
PRIDEiQ17RD7
ProteomicsDBi61148
61149 [Q17RD7-2]
61150 [Q17RD7-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
83851
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000430451; ENSP00000394700; ENSG00000139973 [Q17RD7-3]
ENST00000555409; ENSP00000451035; ENSG00000139973 [Q17RD7-4]
ENST00000568344; ENSP00000478637; ENSG00000139973 [Q17RD7-1]
GeneIDi83851
KEGGihsa:83851
UCSCiuc001xfu.2 human [Q17RD7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
83851
DisGeNETi83851
EuPathDBiHostDB:ENSG00000139973.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SYT16

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0037646
HGNCiHGNC:23142 SYT16
HPAiHPA004199
HPA076871
MIMi610950 gene
neXtProtiNX_Q17RD7
OpenTargetsiENSG00000139973
PharmGKBiPA134964250

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1028 Eukaryota
ENOG410XT5D LUCA
GeneTreeiENSGT00940000159673
HOGENOMiHOG000070178
HOVERGENiHBG062897
InParanoidiQ17RD7
KOiK19328
OMAiEQDNDWS
OrthoDBiEOG091G099X
PhylomeDBiQ17RD7
TreeFamiTF351132

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SYT16 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
83851

Protein Ontology

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PROi
PR:Q17RD7

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000139973 Expressed in 82 organ(s), highest expression level in middle temporal gyrus
CleanExiHS_SYT14L
HS_SYT16
ExpressionAtlasiQ17RD7 baseline and differential
GenevisibleiQ17RD7 HS

Family and domain databases

Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR028690 SYT16
PANTHERiPTHR10024:SF113 PTHR10024:SF113, 1 hit
PfamiView protein in Pfam
PF00168 C2, 2 hits
SMARTiView protein in SMART
SM00239 C2, 2 hits
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYT16_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q17RD7
Secondary accession number(s): B4DZH2
, B7ZL60, C9J8I3, Q707N2, Q7Z441, Q8IUU0, Q9BQR8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 30, 2010
Last modified: December 5, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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